Sila Genc
@drsilagenc
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paediatrics | diffusion MRI | clinical translation | neurology & neurosurgery
Melbourne, Australia
Joined September 2012
🧠New pre-print🧠. In this work we study cortical neurite and soma architecture over development using ultra-strong gradient dMRI 🧲. MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression:
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A study crossing scales, populations (and continents🌏) hopefully contributing to our understanding of how the brain matures over childhood and adolescence. With thanks to all co-authors, collaborators and the families contributing their valuable time to our study 👫.
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Pleased our article is now out in @NatureComms! Link: Using in vivo dMRI data we show distinct maturation patterns of cortical neurite and soma microstructure 🧠.
🧠New pre-print🧠. In this work we study cortical neurite and soma architecture over development using ultra-strong gradient dMRI 🧲. MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression:
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RT @StuartJOldham: The latest from @garedaba .Check it out if you like genes, brains, and/or machine learning!🧬🧠🤖.
www.nature.com
Nature Communications - The third trimester of human gestation is characterised by rapid increases in cortical surface area. Here, authors show that increased rates of cortical expansion are...
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Now published in @netneurosci - happy to see this one out!.
direct.mit.edu
Abstract. In response to a growing interest in refining brain connectivity assessments, this study focuses on integrating white matter fiber-specific microstructural properties into structural...
New pre-print🧠By incorporating microstructural information into network analyses we show ongoing development of the visual cortex over childhood and adolescence. A great collaboration with @simonaschiavi24 and colleagues during our time @CUBRICcardiff!.
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Beautiful work from @bradleykarat detailing microstructural development of the hippocampus!.
🍤 time! . In this new pre-print we used ultra-strong gradient dMRI to investigate the neurite and soma development of the hippocampus in childhood and adolescence. "The developing hippocampus: Microstructural evolution through childhood and adolescence":
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RT @bradleykarat: 🍤 time! . In this new pre-print we used ultra-strong gradient dMRI to investigate the neurite and soma development of the….
www.biorxiv.org
The hippocampus is a structure in the medial temporal lobe which serves multiple cognitive functions. While important, the development of the hippocampus in the formative period of childhood and...
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This work adds to a growing body of evidence that intra-cortical myelination continues through adolescence into adulthood. Work done @CUBRICcardiff with the combined brain power of @garedaba @MaxChamb @erikaraven @ChantalTax @IsobelLWard @NACIS_RCH @MarcoPalombo3 & @Dee_Kay_Jay!.
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To help interpret our dMRI findings we analysed two ex-vivo human gene expression databases. Patterns of gene expression pointed to increasing expression levels of oligodendrocyte cell-types with age, enriched in adolescence and young adulthood.
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Cortical volume loss and thinning 📉 are hallmarks of child🧒 and adolescent👩🦰 brain development. But what are the underlying cellular properties driving these cortical changes?
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RT @eurekaprizes: MRtrix3 @MRtrix3 is a finalist in the @ARDC_AU Eureka Prize for Excellence in Research Software. Learn more: https://t.c….
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RT @MRtrix3: Our next MRtrix workshop is less than 4 weeks away! There are still places available if you’re interested – you can sign up vi….
www.mrtrix.org
posted by Chun-Hung Yeh on Jan 20, 2024
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First thing, last day, my talk on cortical microstructural development 🧠 a final chapter in my work @CUBRICcardiff . Thur 8:15am.Pediatric Neuro.Nicoll 3. See you there!. #ISMRM2024 #ISMRM24
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RT @MaxChamb: I have a 3rd PhD opening on Real-Time Rendering of Diffusion MRI Tractography Data - DM for more info .
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New pre-print🧠By incorporating microstructural information into network analyses we show ongoing development of the visual cortex over childhood and adolescence. A great collaboration with @simonaschiavi24 and colleagues during our time @CUBRICcardiff!.
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RT @NACIS_RCH: @MCRI_for_kids Proud to represent at the MCRI Symposium 2023. Well done, team! @drsilagenc @BonnieAlexandr, Dr Ashkan Pakza….
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RT @StuartJOldham: 🌈🌈It's finally (officially) out!🌈🌈 @garedaba and I take a look at gradients/axes of thalamocortical connectivity in the….
www.nature.com
Nature Communications - The principles underpinning the projection patterns of the thalamus to the cortex are not well characterised. Here, the authors reveal a medial to lateral thalamic gradient...
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RT @simonaschiavi24: Finally out my last work as an academic! with the amazing collaborations between @br_igh_ten @….
onlinelibrary.wiley.com
We present a novel robust and clinically feasible 10-min diffusion MRI protocol with b values up to 6000 s/mm2 for 3 T which can reliably assess gray and white matter microstructure according to the...
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