Jo Carpenter
@drjoeyjoeyjojo
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Youth mental health researcher @BrainMind_Usyd The world needs more kindness, fairness, knowledge, and humour. Be the good. Spread the love.
Sydney, New South Wales
Joined October 2018
What's next: - Is correction of this circadian misalignment is relevant to treatment outcomes? More longitudinal studies are needed! - Circadian phase measures are costly and burdensome- are there better ways to detect circadian abnormalities e.g. mathematical modelling of phase?
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What's new: - The first study in mood disorders to look at 3 different biological phase markers in tandem - Individuals presented with a diverse range of individual phase abnormalities - Relative timing of melatonin and temperature rhythms may be key features linked to symptoms
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Key findings: - 23% of youth with emerging mood disorders had internal misalignment where 2 or 3 of the circadian rhythms we measured were out of sync (phase angles>2SD of controls) - Greater circadian misalignment on some measures was associated with greater depression severity
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Our latest paper showing evidence for internal circadian misalignment in mood disorders! https://t.co/Wh3xdUqyFe A thread🧵: @ian_hickie
@JacobJCrouse
@Zsofi_deHaan
@mirim_shin
@emilianatonini
@frankiorfino
@BrainMind_Usyd
@Sydney_Uni
@SageJournals
@SRBR_Outreach
journals.sagepub.com
Despite evidence for links between circadian dysfunction and mood disorders, previous research has largely reported on single biological markers of circadian al...
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Cross-sectional and longitudinal associations between cardiometabolic measures and clinical stage in young people https://t.co/4Ofly032CZ Recognizing that physical health challenges are present early in the course of major mood and psychotic disorders; @IEPAnetwork @PatMcGorry
pubmed.ncbi.nlm.nih.gov
Whilst no relationships were found between demographic or cardiometabolic variables and clinical stage at entry to care, an increased BMI over time was associated with clinical stage transition...
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PUBLICATION | Our paper on clinical staging and the differential risks for clinical and functional outcomes in young people presenting for mental health care is now out in @BMCMedicine
@ian_hickie @mirandarwolpert @DrJaiShah @SPMCross @PatMcGorry 🧵1/8 https://t.co/7P3F6VxMVX
link.springer.com
BMC Medicine - Clinical staging proposes that youth-onset mental disorders develop progressively, and that active treatment of earlier stages should prevent progression to more severe disorders....
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Does circadian dysrhythmia drive the switch into high or low activation states in bipolar I disorder? https://t.co/dymHJiROx1 Summary of evidence that circadian perturbations may drive key switches between major mood-motor states; @mirandarwolpert @NIMHDirector @CircadianClocks
pubmed.ncbi.nlm.nih.gov
Based on the reviewed evidence, our view is that circadian dysrhythmia is a plausible driver of transitions into high- and low-activation states and deserves prioritisation in research in bipolar...
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We are looking for a research fellow to join our team @BrainMind_Usyd, with a focus on sleep and circadian rhythms in youth mental health! 😴⏰🧠 If this is you, please apply by August 25! https://t.co/fAQWXwpg24 Please retweet! @ian_hickie @syd_health @IEPAnetwork @SMHR
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Looking after our circadian rhythms is so important for our physical and mental health. Lockdown is a whole new challenge.
Circadian rhythms and mental health in lockdown … @JacobJCrouse et al write #freeaccess in InSight+ … "lifestyle changes indicate disruption in factors related to circadian system which may partly explain changes in mood & mental health" https://t.co/WlOk4llvPj
#medtwitter
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Getting bright light in the day is as important as avoiding light at night. We looked at outdoor light exposure in >400,000 people - more light: better mood, less risk of depression, lower antidepressant use, better sleep. Get those free photons! 🌞 https://t.co/ioocIHLvWm
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📣 Great opportunity to examine digital tech and childhood wellbeing, on a global scale! 🌍 Our team @BrainMind_Usyd is hiring an Evaluation Research Fellow to assess the impacts of an app on the socio-emotional wellbeing of children aged 0-5. Please RT! https://t.co/G7Bc9LWzWb
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"There is no waiting list for emergencies, but we don't want this to be a young person's entry point to care." Dr @frankiorfino describes better entry pathways to mental health care in this research report enabled by our partnership with @BupaAustralia
https://t.co/enZv85BtzK
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Get outdoors if you can! Get those #circadianrhythms going
With the weekend here- time spent in outdoor light 🌞 = GOOD for your health. Study by @circadian247 & co found reduced risk for low mood & depression, ⬆️ happiness, greater ease of getting up, ⬇️ tiredness, & ⬇️insomnia the more people got outdoor light.
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Our latest paper presents the case for disrupted circadian rhythms as an active ingredient in depressive disorders. Led by @JacobJCrouse – see thread for an excellent summary. Including the voices of young people with #livedexperience has been so important to shape our approach!
Circadian clocks and #depression in young people - out now in @TheLancetPsych! Kudos to @mirandarwolpert + @wellcometrust for lifting #livedexperience and thinking of new ways forward. Thread below! 🧵 #ActiveIngredientsMH #mentalhealth @ian_hickie
https://t.co/fUn1ejzyi1
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Can vouch it's a wonderful team! Come and join it.
We are looking for someone interested in undertaking research in adolescent depression to join our team at @BrainMind_Usyd. This work is generously supported by the Anika Foundation PhD Scholarship. @ian_hickie @YOUTHe_au @SydneyUni_Media
https://t.co/kJmwYWUPXx
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"Being in lockdown is not fun..." A timely podcast episode for today as NSW extends restrictions. Catch up on this week's episode of Minding your Mind as @ian_hickie and @Jamesologhlin discuss: What can you do to protect your mental health during lockdown? https://t.co/kJjyFuVnyT
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@ian_hickie & @Jamesologhlin have drop a new podcast #MindingYourMind; diving into how our minds work & #MentalHealth - breaking down jargon + misconceptions to better our understanding. Listen on @ApplePodcasts 👉🏻 https://t.co/Pine7OBPlo or @Spotify 👉🏻 https://t.co/R58tcZikVu
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We're almost there! With tomorrow's winter solstice we can start looking forward to more light & better #circadian rhythms. But regulating light isn't just about bouncing out of bed in the morning- research shows why body clocks matter in #mentalhealth . https://t.co/CVLCeK16sY
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My Fellow Night Owls - Fight for your right for later start times - science is on our side. #NobelPrize #circadian
Listen to Nobel winner Michael Young talk about his lab's discovery of the #clock gene variant responsible for DSPD, a #sleep disorder where subjects have natural tendency to sleep late and be night owls. @FralinBiomed
https://t.co/fl7g2INcHk
@CSD_N @ResearchSleep @ESRS_Sleep
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While we're talking about sleep this week, our youth mental health team has a new paper out, shedding light on circadian rhythms as a mechanism of some #mentalhealth disorders, not just a symptom. https://t.co/W1Xf0v3cuO
@joannecarpenter @JacobJCrouse @ian_hickie @Prof_Naismith
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