Deji Adegunsoye, MD, PhD
@drdayjee
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Physician, Dad, Assistant Professor @UChicagoMed| Intensivist |Pulmonologist🫁|Geneticist🧬| Fighting #PulmonaryFibrosis |Opinions=mine only
Chicago, IL
Joined April 2017
🔥🔥🔥Excited to share our latest review in AJRCCM delving into intricate genetic & epigenetic frameworks shaping #pulmonaryfibrosis & unraveling its complexities. Grateful for collaboration with @JKropski @AnnaPodolanczuk @jskim8223, & all contributors. https://t.co/FuOQHnn7t5
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Overheard at #ECPPILD2025 today in Orlando: ""The prevalence of ILD is increasing and may be even higher than estimated because of failure to recognize the disease in clinical practice. We have the tools to better manage ILD, but recognition is key!" - @drdayjee Deji Adegunsoye,
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Dr Ayodeji Adegunsoye – statement Co-Chair – gives a brief overview on the new Update of the International Multidisciplinary Classification of the Interstitial Pneumonias: An ERS/ATS Statement 📽️ 📖 Watch now on our ERS LinkedIn channel: https://t.co/MLkwW30E0f
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Deji Adegunsoye, MD, MSc, PhD, FCCP (@drdayjee) brings expertise as Scientific Director of the ILD Program at @UChicagoMed to the 2025 Early Career Preceptorship Program on ILD! Join him for insights on multidisciplinary approaches to optimizing patient care. 🔗
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Excited to share our study that is online @ThoraxBMJ examining clinical trajectories by ILD subtype and CT UIP pattern https://t.co/8flG2CcH7f
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Our newest paper: “Predicting lung aging using using single cell RNASeq data״ see thread below 👇🏼 https://t.co/h0WbkuD4qF
journals.plos.org
Author summary Aging is characterized by several changes at the cellular and molecular levels. The type and rate of these changes varies between individuals and does not always correspond to their...
1/n Just in time for the Holidays "Predicting lung aging using #scRNASeq data" is out!! #NormalLungAgingCellAtlas team report sa novel method that predicts lung age in smokers and non-smokers. Kudos lead authors, Drs Song, Bar-Joesph & team. See 🧵below https://t.co/4Vh4u3Oolh
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My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. It’s available on Amazon: https://t.co/VKR3l4RTSA
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Really cool! Our ‘Single-Cell Analysis Reveals Novel Immune Perturbations in Fibrotic Hypersensitivity Pneumonitis’ is on cover of the American Journal of Respiratory & Critical Care Medicine. Kudos to soon to be #DoubleDoc Amy Zhao & crew!! #BestStudents
https://t.co/xaxllX5YtZ
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Truly honored to be the keynote speaker at this incredible event! I loved every moment in Toronto, meeting such inspiring minds and learning about the amazing work you all are doing in pulmonary fibrosis. Thank you for the warm welcome and the inspiration!🙏🏽🇨🇦
@jolenehfisher, @twhcmr and I were honored to have @drdayjee at our @UofTRespirology #ILD educational day. He gave a fantastic talk on genetics of ILD and biomarkers: past, present and future. Thanks @drdayjee for coming along the way to Toronto to enhance our event! 🙏🙏🙏
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Belated ICLAF appreciation post - such a wonderful time with amazing people and great science in a beautiful location! Athens was amazing! #ICLAF2024
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@drdayjee @KerriBerriKerri @atzouvelekis @PilarRiveraOrt1 @AnnaPodolanczuk @ericafarrandMD @Eickelberg_MD @DrPeter_George @leticiakawano @RealEricJWhite @LouiseVwain @GlassbeMK @JVPugashetti @aravindamenon @MTFreeberg @rachelkputman @glaspoletweet @NaamaAvitzur Truth is - what I love most in Athens & in Greece - the people - their resilience, activism, energy and generosity 🥰
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@KaminskiMed @KerriBerriKerri @atzouvelekis @PilarRiveraOrt1 @AnnaPodolanczuk @ericafarrandMD @Eickelberg_MD @DrPeter_George @leticiakawano @RealEricJWhite Day or night, the landscape dazzled with magnificent structures and breathtaking views—an awe-inspiring spectacle at every turn! 🏛️ #ICLAF2024
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Athens: where medicine, democracy, philosophy, and the Olympics were born! This ancient city isn’t just a historical wonder—it’s a feast for the eyes, overflowing with culture, charm, and jaw-dropping views.
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Still basking in fun times & learnings from Athens🇬🇷 this week at #ICLAF2024: • multiomics of pulmonary fibrosis 🫁 • novel pathophysiologic findings 🧬 • potential therapeutic targets 💊 • …and of course, insights into Greek mythology🏛️ #ScienceWin #MedTwitter #CurePF
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Delighted to share our new study led by @AitanaAG90 evaluating the association of rare variants in telomere and non-telomere monogenic adult-onset Pulmonary Fibrosis genes and IPF patient survival where we also intersected their effects with #PRS of IPF.
medrxiv.org
Background The clinical course of idiopathic pulmonary fibrosis (IPF) is highly variable and unpredictable, with multiple genetic variants influencing IPF outcomes. Notably, rare pathogenic variants...
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Dr. Marilyn Glassberg delivers an outstanding talk on sex differences in pulmonary fibrosis. • need early disease models • being female appears to be protective. • Nitrogen mustard model is quite similar to Bleo • Estrogen did not seem to stimulate fibrosis #ICLAF2024
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Dr Bruno Crestani elegantly discusses endocrine fibroblast growth factors • have paracrine functions +/- exert antifibrotic/profibrotic effects • FGF23 ⬆️ in fibrotic lung • FGF19 analogs improved fibrosis in NASH, not ⬆️ in the lungs & ⬇️ in IPF plasma. #ICLAF2024
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• No association between abundance of s. Mitis and mortality risk. • progression of disease linked to loss of s. mitis over time. @jskim8223
#ICLAF2024
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Dr. David O’Dwyer deliver a fantastic talk on oral dysbiosis in IPF. • Discusses lessons learned from the Clean-Up IPF trial. The Streptococcus genus dominates the buccal microbiome #ICLAF2024
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@drphilmol • At diagnosis more bacteria +short chain fatty acids in IPF • clear association between microbes & SCFA in the lungs • bacterial burden strongest mortality signal. • Propionate significantly affects primary bronchial epithelial cells to impair wound healing. #ICLAF2024
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•The Microbiome changes during acute exacerbations •Demonstrates how this understanding raises a lot of important and unanswered questions •Can treating help? @drphilmol #ICLAF2024
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