Complex Portal
@complexportal
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The Complex Portal is a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms. Also follow➡️@intact_project
Hinxton, England
Joined June 2017
UniProt is taking part in the @EMBO Computational Structural Biology workshop in @EMBLHeidelberg from 2nd to 5th December. Conny Yu will be presenting poster 195 ‘UniProt as a central hub for structure-function analysis’. Visit the @EMBOComp3D webpage: https://t.co/u1ItywE7zp
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New ProteinSpotlight blog post Have you ever wondered where the feeling of thirst comes from? Discover how TMEM63B acts as an osmosensor deep in the brain to remind us to take a drink. Read the blog here: https://t.co/OrVmkaIcU9
@ISBSIB
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From a farm in the north of England to the frontiers of bioinformatics, our Group Leader Sandra Orchard reflects on a career building the data foundations of modern biology: “AI is showing how vital data curation really is.” https://t.co/x5TLvFmYn8
#biocuration #FAIRdata
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Upon her retirement from EMBL-EBI, we thank Sandra for her dedication and foundational work for important open data resources including: @uniprot
@complexportal
@intact_project
@news4go
@InterProDB
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Registration is free but essential: https://t.co/mIcb2JJio4 Speakers: Susie H. and Eliot Ragueneau #Bioinformatics #IntAct #Modelling #BiologicalNetworks #Cytoscape
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Would you like to learn more about molecular interactions & to explore them across organisms? Join us next week for an introductory webinar where we walk through the IntAct's approach to molecular network modelling & show how this is implemented within the IntAct Cytoscape app.
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Meet Jana Broecker 🇩🇪 who helps build bridges between EMBL-EBI and industry. As a Senior Scientific Officer in our Industry Partnerships team, Jana enables knowledge sharing and technology transfer, focusing on bioinformatics and data sciences. https://t.co/dOpNSg6e9e
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Follow the link to uncover: 🧩 what the complex does in the cell 🔄 pathways it participates in (Reactome) 🧬 curated disease links (EFO, MONDO, OMIM). PDBe for structure — the Complex Portal adds the biology. Together they tell the full story: structure → function → system.
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🔬 Noticed the new look PDBe? The refreshed Protein Data Bank in Europe now includes direct links to the Complex Portal! Example: PDB 6OOY → TNFA complex (CPX-8826).
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There’s still time to register for our webinar on the upcoming changes to the UniProt Proteomes database. Learn how Proteomes and UniProtKB will change and how this might affect you. Thursday 23rd October 15.00 (BST) Registration is free but essential; https://t.co/eMb7BTOZ0N
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📥 Submit your data here: 🔹 IntAct: https://t.co/A7dsJpVoNO Let’s make your science more FAIR - Findable, Accessible, Interoperable, and Reusable. #Biocuration #FromBenchToDatabase #FAIRdata #ProteinInteractions #EMBLEBI #IntActEBI #OpenScience #UniProt #DataMatters
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Want your PPI or structural data to make an impact? ✅ Use Identifierss ✅ Include structured tables (e.g. Niri et al. 2021 - PMID: 34197713) ✅ Submit to EMBL-EBI's data resources - IntAct 👉 See Niri’s dataset in IntAct: https://t.co/uHhIYN9SZI
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Don’t just publish - be found! 🔍 I didn’t realize how vital biocuration was until I became a curator. A well-curated dataset doesn’t just sit in a paper - it lives on in databases and fuels new discoveries.
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🔗 Explore CPX-6502 ( https://t.co/XtTGQbUoub), via the @emblebi Complex Portal - mapping all biologically functional protein complexes. #GlobalPNHAwarenessDay #PNH #RareDisease #GPIAnchors #ComplementSystem #GpiGnT #ComplexPortal #EMBLEBI
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🧬 On #GlobalPNHAwarenessDay, we spotlight the GPI-GnT complex — a key enzyme disrupted in PNH, a rare and life-threatening blood disorder. 🧩 Its failure (often via PIGA mutations) removes GPI-anchored proteins, leaving blood cells unprotected from complement attack.
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We’re renewing our collaboration with @GoogleDeepMind! We'll keep developing the AlphaFold Database to support protein science worldwide 🎉 To mark the moment we’ve synchronised the database with UniProtKB release 2025_03 https://t.co/VTzPuEUC1r
#AlphaFold
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Did you know big changes are coming to UniProt Proteomes? Learn how UniProtKB will change and how this might affect your work in our next webinar 📆Thursday 23rd October 15.00 (BST) 📷 Registration is free but essential https://t.co/sxYASfa4g4
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🔬 See also: https://t.co/kF4TAcs1sz
https://t.co/raPa6eIdxT
#MinorSpliceosome #RNAsplicing #snRNP #U12Introns
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🔬 See also: https://t.co/kF4TAcs1sz
https://t.co/raPa6eIdxT
#MinorSpliceosome #RNAsplicing #snRNP #U12Introns
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