Chris Zerio
@chriszerio
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Scientist
San Diego, CA
Joined July 2012
Very excited to see my main postdoctoral research project peer-reviewed and published! We used cryoEM and biochemical experiments to uncover how Polymerase θ helicase facilitates DNA microhomology annealing to repair DNA in BRCA-deficient cancers. Paper:
nature.com
Nature Structural & Molecular Biology - Here, Zerio et al. use cryo-electron microscopy to show how the helicase domain of DNA polymerase θ aligns broken DNA strands by matching short...
A DNA repair enzyme that some cancers rely on to survive could be the key to more precise treatments. The @LanderLab has captured the first images of Pol-theta in action, revealing how it repairs DNA—offering a blueprint for better cancer therapies. More: https://t.co/sFKwXTUFUW
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Thrilled to share my postdoctoral work in @Landerlab! The human Polymerase θ helicase undergoes conformational rearrangements to facilitate DNA microhomology annealing. These insights enable rational design of novel BRCA-deficient cancer therapeutics! https://t.co/DWsLxdJtah
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Our first foray into the fascinating field of DNA repair! Congrats to postdoc Chris Zerio @chriszerio, who tested hundreds of oligos to identify one that trapped the helicase of human Polymerase θ in the process of annealing two strands of DNA. https://t.co/vKldWuTd8x
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A compilation of photos from the past couple of days at the @CSHL Cryo-EM course! Late night data processing, manual plunging grids, and clipping grids! @cshlcourses #CryoEM @LanderLab @chriszerio
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Scientists led by @LanderLab uncover a critical feature that a promising new class of #cancer drugs needs to be effective. These drugs need to cause specific shape changes in their target that can then trigger the breakdown of key cancer-driving proteins https://t.co/6WakQ78gkk
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Fantastic talk by @ChrisZerio who is off to postdoc for @LanderLab in what is apparently the greatest EM lab 😊😊. He did a wonderful job with his talk, his acknowledgments were incredible. It was a treat!!!
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.@ChrisZerio had an incredible 4-yr career with the Loggers: 3x All-NWC selection and an All-West Region honoree. He has the second-best career BA in Logger history at .370. A stellar student Zerio is working on his PhD in Pharmaceutical Sciences at the Univ. of Arizona.#LoggerUP
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.@PS_baseball senior Chris Zerio has been named the Logger of the Week! #LoggerUP
https://t.co/787sDfbGVs
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Logger Sports Network: 2016 season preview - interviews with HC Halstead, Zerio, Funyak, and Croney. #LoggerUP
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SEASON PREVIEW: The Loggers look to build off of record-setting 2015; 2016 campaign starts this weekend. #LoggerUP
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Our baseball field is getting new stadium seating for this season! Thank you so much to the Cheney Foundation! http://t.co/j28kcrz6iH
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Connor Savage and Chris Zerio named to ABCA/Rawlings All-Region West Team. #LoggerUP
http://t.co/wQ4My6HyEu
http://t.co/C6lw328Mt4
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