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Chng Wee Joo Profile
Chng Wee Joo

@chngwj

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421
Following
180
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39
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132

Clinician Scientist | myeloma doc | Amateur Photographer | soccer fan | movie fanatic | comic book heroes

Singapore
Joined July 2017
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@chngwj
Chng Wee Joo
3 months
RT @IMFmyeloma: IMF's International Myeloma Working Group brings together global experts dedicated to advancing myeloma research. At the upโ€ฆ.
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@chngwj
Chng Wee Joo
3 months
This work that was beautifully done by Mun Yee Koh and supervised by @Pjteoh. Input from @Pollych34650771 is always invaluable. Thanks to @DrSarahGooding for an excellent editorial on the paper.
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@chngwj
Chng Wee Joo
3 months
When ADAR1 is over-expressed in 1q21 amplified myeloma, the cells are able to rapidly edit and degrade the dsRNA, resulting in attenuation of the dsRNA sensing pathway response and resistance to treatment.
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@chngwj
Chng Wee Joo
3 months
Mutations in the cereblon pathway, which is the direct target of drugs such as Lenalidomide and Pomalidomidie, are relatively rare causes of clinical resistance. One of the more common genetic association with resistance to Lenalidomide is chromosome 1q21 gain.
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@chngwj
Chng Wee Joo
3 months
Better late than never! Wanted to highlight a recent piece of work from our lab where we discribed a novel mechanism of action of lenalidomide and resistance mechanism (.
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ashpublications.org
Key PointsLenalidomide induces immunomodulating responses through the activation of dsRNA-sensing pathway.ADAR1 drives lenalidomide resistance in MM via th
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@chngwj
Chng Wee Joo
3 months
Have to come all the way to Japan to see @NBahlis! So nice to see him at the excellent Japanese Society of Myeloma meeting this weekend. [with President of JSM Dr Iida in photo] #mmsm
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@chngwj
Chng Wee Joo
4 months
So happy to be able to contribute samples and data to this study!.
@astar_gis
A*STAR Genome Institute of Singapore (A*STAR GIS)
4 months
๐Ÿš€ Exciting News from Singapore! ๐Ÿš€. Scientists at A*STAR's Genome Institute of Singapore (@astar_gis) have unveiled one of the world's largest long-read RNA sequencing datasets! ๐ŸŒ๐Ÿ”ฌ This groundbreaking resource, known as SG-NEx, is set to revolutionize disease research by.
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@chngwj
Chng Wee Joo
5 months
Thanks so much for highlighting our latest work identifying a novel mechanism of action and resistance to immunomodulatory drugs in myeloma. #mmsm.
@csi_singapore
CSI Singapore
5 months
We would like to congratulate our CSI PIs, @chngwj @Pollych34650771 & team!.
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@chngwj
Chng Wee Joo
5 months
So privilege to be involved in this study!.
@astar_gis
A*STAR Genome Institute of Singapore (A*STAR GIS)
5 months
Congratulations to @JonathanGoeke, @chenying927 and our @astar_gis team on your SG-NEx project, providing a comprehensive resource that enables the development and benchmarking of computational methods for profiling complex transcriptional events at isoform-level resolution.
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@chngwj
Chng Wee Joo
9 months
Beautiful sunrise from up above as I travel to San Diego for #ASH24 !
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@chngwj
Chng Wee Joo
9 months
RT @VincentRK: The new Scientific Advisory Board (SAB) @IMFmyeloma will guide all our research activities. #myeloma
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@chngwj
Chng Wee Joo
10 months
So happy to invite @Leif_Bergsagel to speak at #fcs2024 and host him and Marta for a couple of days in Singapore! They did a lot but still have loads more to explore!
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@chngwj
Chng Wee Joo
10 months
Had the honor of hosting @DrRakeshPopat in Singapore with the #mmsm team! Great discussions on T cell engagers and potential areas of collaborations!
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@chngwj
Chng Wee Joo
10 months
Thank you so much for joining our summit. We are grateful for @IMFmyeloma continues strong support and also @VincentRK fantastic insights that is so relevant to our region!.
@NorthTxMSG
Yelak Biru
11 months
Dr @VincentRK giving the keynote lecture at the 8th Annual Asian Myeloma Network Summit in Seoul, Korea. "Improving Outcomes With Limited Resources!"
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@chngwj
Chng Wee Joo
11 months
RT @VincentRK: Iโ€™m in Seoul for the @IMFmyeloma Asia Myeloma Network meeting. @NorthTxMSG @chngwj
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@chngwj
Chng Wee Joo
11 months
RT @NorthTxMSG: Today, in seoul, Korea, we kicked off @IMFmyeloma's Asian Myeloma Netowrk 4th Mastetclass Program. Over 60 junior clinicianโ€ฆ.
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@chngwj
Chng Wee Joo
11 months
Very grateful for the years of support and honored to receive this award!.
@NUSMedicine
Yong Loo Lin School of Medicine
11 months
๐ŸŽ‰ Congratulations to Prof Chng Wee Joo @chngwj, Prof Lee Soo Chin, Prof Jimmy So Bok Yan, and Assoc Prof Reshma Merchant @reshmaamerchant from #NUSMedicine on receiving the Distinguished Senior Clinician Award! ๐Ÿ‘
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@chngwj
Chng Wee Joo
11 months
RT @gjmccaughan: At our @ALLGtrials and Asian Myeloma Network #NORM #MM26 Poster at #IMS24 - our platform study in orphan subgroups of MM (โ€ฆ.
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@chngwj
Chng Wee Joo
1 year
Honored and privileged to be appointed to the IMF SAB! Look forward to working with international colleagues towards ultimate goal of curing #mmsm!.
@NorthTxMSG
Yelak Biru
1 year
We thank ๐ƒ๐ซ. ๐๐ซ๐ข๐š๐ง ๐†.๐Œ. ๐ƒ๐ฎ๐ซ๐ข๐ž ๐Ÿ๐จ๐ซ 35 ๐˜๐ž๐š๐ซ๐ฌ ๐จ๐Ÿ ๐‘๐ž๐ฆ๐š๐ซ๐ค๐š๐›๐ฅ๐ž ๐‹๐ž๐š๐๐ž๐ซ๐ฌ๐ก๐ข๐ฉ! and @IMFmyeloma ๐€๐ง๐ง๐จ๐ฎ๐ง๐œ๐ž๐ฌ ๐š ๐๐ž๐ฐ ๐’๐œ๐ข๐ž๐ง๐ญ๐ข๐Ÿ๐ข๐œ ๐€๐๐ฏ๐ข๐ฌ๐จ๐ซ๐ฒ ๐๐จ๐š๐ซ๐!
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