Nick H
@breakfastnick
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Ten words you need to know to understand how we can be entering the seventh year of the covid pandemic.
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Talking Again in 2025 I started eating again in 2024. After 11 years not eating a crumb of food or even drinking a drop of water. I got all fluids and nutrition from tubes inserted into my body. For 11 years. In 2025 I have another big improvement to announce. I have
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Researchers studied 99 COVID-19 patients and found that SARS-CoV-2’s nucleocapsid protein can trigger complement activation even without matching antibodies. This suggests the N protein may play a larger role than spike in severe immune overreactions. https://t.co/prvdaOWG6K
nature.com
Scientific Reports - In vitro complement activation via nucleocapsid and spike proteins of SARS-CoV-2 in COVID-19 patients
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UC Irvine scientists report that Long COVID may be driven by hidden reservoirs of SARS-CoV-2 lingering in organs for months or years. These reservoirs keep the immune system overstimulated, leading to fatigue, brain fog, and organ damage. https://t.co/z5U1NCCQZ0
mdpi.com
Long COVID (LC), also known as post-acute sequelae of COVID-19 infection (PASC), is a heterogeneous and debilitating chronic disease that currently affects 10 to 20 million people in the U.S.
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It can feel lonely navigating the #LongCOVID a life-changing disease that affects over 400 million people worldwide. Sign up for our newsletter and join others who want fact-based news without COVID-19 denial, minimizing, or gaslighting. https://t.co/ZSY5E2SlOB
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I’ve spent 3 years photographing people with #MECFS, a condition I’ve lived with since 1987. 50 people. Invisible & incurable illness. The work shows at Oxo Tower in September. Updates & book info here: https://t.co/XKdL5WrOEz
#InvisibleIllness #PhotographyForChange
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.@SecKennedy opens the Long COVID Consortium at HHS, stating he convened today’s roundtables for people who “don’t know where to go, and feel their voices aren’t being listened to.”
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@SecKennedy @RogerMarshallMD @DrMakaryFDA @NIHDirector_Jay @LongCFoundation @PutrinoLab @DrBobRedfield51 @NIH @Invivyd @polybioRF @brucep13 @MichaelPelusoMD @ARPAHealth It sounds like some real news was just made today by @SecKennedy @HHSGov: it appears @ARPAHealth WILL now take on #LongCOVID for the first time, after two years of patient advocacy & outreach! A huge testament to our Hill partners & community engagement. #HHSLongCOVID 14/x
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Tomorrow's HHS gathering of #LongCOVID experts is a critical meeting & opportunity for US patients. If I could share "Five Ideas Secretary Kennedy Could Just Decide Today" with these high-level officials—that don't require any new legislation, rules or funding now—they'd be: 1/x
Just announced: HHS Secretary RFK Jr. is hosting two "roundtable discussions" about Long COVID tomorrow at 2 p.m. ET. @thesicktimes will be covering the event and reactions from the Long COVID community. (Reach out if you'd like to send us comments during or after!)
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UCSF researchers review new evidence showing Epstein-Barr virus is not just linked but required for multiple sclerosis. Nearly 100% of MS patients have prior EBV infection and risk rises 32-fold after catching the virus. https://t.co/VbT7zm8LYy
neurology.org
Epstein-Barr virus (EBV) is a very common herpesvirus that infects more than 90% of the general population. Epidemiologic data indicate that EBV is a requisite risk factor for the development of...
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NEW @thesicktimes: RECOVER-TLC announces new clinical trials, responses from the Long COVID community are mixed. Story includes new info from today's workshop & comments from NIAID's Joseph Breen:
thesicktimes.org
Some Long COVID advocates and researchers, including those who advised the National Institutes of Health’s initiative, say RECOVER-TLC isn’t living up to its promised ambition.
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The complement system detects & eliminates pathogens; however, when overactivated, it can become harmful to the host. Rafael Bayarri-Olmos et al. summarize the latest understanding of the role of complement in #LongCOVID pathogenesis (open access)👇🏼 (1/) https://t.co/7jdUVw7Ba7
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We discovered that SARS-CoV-2 spike protein persists in the body & brain borders years after infection, driving inflammation & brain vulnerability, a mechanism for Long COVID. 🧠 https://t.co/IEGx7HIrXf 💉 Vaccine: https://t.co/1YniGZqwYw 🔬 Method: https://t.co/2sPQra6sHZ
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“Many controls who didn’t identify as having #LongCovid, filled out questionnaires indicating they did have it.” — @AzolaAlba, Johns Hopkins School of Medicine #KeystoneSymposia
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Oxford researchers tracked 576 people in the UK with long-lasting COVID infections and found that while most showed little viral change, a small group developed rapid mutations, some matching those in known variants. Late-stage transmission was rare. https://t.co/tpZdbfNhVx
thelancet.com
This study highlights the heterogeneous nature of within-host SARS-CoV-2 evolution in individuals with persistent infection in the community. Notably, a small subset of persistent infections with...
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Paris researchers studied golden hamsters and found that SARS-CoV-2 can persist in the brainstem for 80 days, triggering gene changes linked to neurodegeneration and causing depression-like behavior, memory loss, and anxiety-like symptoms. https://t.co/wF2YulVkTy
nature.com
Nature Communications - SARS-CoV-2 persists in the brainstem long after the initial infection has passed. Infected animals exhibit symptoms of anxiety, depression, and memory impairment as well as...
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Torrance and Phoenix researchers analyzed blood from 14 long COVID patients and found SARS-CoV-2 peptides in serum extracellular vesicles, suggesting a potential biomarker for lingering viral activity. https://t.co/zzVdCe3pRg
link.springer.com
Infection -
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Hepatitis C Found in Brain Lining Linked to Schizophrenia, Bipolar Disorder A new study reveals hepatitis C virus (HCV) in the brain lining of people with schizophrenia and bipolar disorder, suggesting infection may play a role in these psychiatric conditions. Researchers
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REPLACEMENT OF AUTOIMMUNE (AND RHEUMATOLOGICAL) DISEASES WITH INFECTIOUS DISEASES THAT CAUSE AN AUTOIMMUNE RESPONSE We reaffirm that the root cause is environmental agents primarily microorganisms https://t.co/b4CqPJeajm Also applicable to: Cancer Atherosclerosis Alzheimer Others
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