Bob Hoffman MD
@bobhoffmd
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Spending a life time trying to figure out the best way to care for poisoned patients. Opinions presented are reflective of my personal view only
New York
Joined February 2012
Great images demonstrating POUNCE syndrome. Some free downloads available here if you are interested.
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This is a good example of what can go wrong when preliminary animal data is used to treat human patients. Some free downloads here.
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RT @Clin_Tox: It's here! The 2022 Annual Report of the National Poison Data System (NPDS)! . In 2022, over two million human exposures were….
tandfonline.com
This is the 40th Annual Report of America’s Poison Centers National Poison Data System (NPDS). As of 1 January, 2022, all 55 of the nation’s poison centers (PCs) uploaded case data automatically to...
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Congratulations to coauthors Brian Wiener, Cameron Smith and Savan Patel for a really great report "Insulin concentrations following termination of high-dose insulin euglycemic therapy" a few free downloads are available here:
tandfonline.com
High-dose insulin therapy is used in patients with calcium channel blocker and beta-adrenergic antagonist overdoses. The pharmacokinetics of insulin are scantly reported following high-dose insulin...
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How well can we predict normalization of lithium concentrations in patients with chronic overdose based on kidney function? Curious? Downloads available from a recent publication in Clinical Toxicology
tandfonline.com
Published in Clinical Toxicology (Vol. 60, No. 9, 2022)
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After a more than 20 year hiatus our study guide returns in print. Thanks Rana for an amazing job as the project leader!
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With fomepizole for ADH blockade death and progression of AKI were almost nonexistent when the anion gap was less than 24mmol/L and mostly observed when the anion gap was greater than 28mmol/L. Download at if you don't have access
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RT @DrTsion: I am honored to host all my former teachers from NYU/Bellevue residency program to present at the Ethiopian Emergency Society….
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if you would like to read and interesting case of a young woman with seizures there are 50 free downloads here:
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50 free downloads are available to those with no access through this link. Great collaborative effort.
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RT @DevinJBurkeMD: “Initiation of metformin in MELAS patient–a dangerous combination.”Great collaboration with @ToxNyu @jtrebach @sarah_mah….
tandfonline.com
Published in Clinical Toxicology (Vol. 60, No. 3, 2022)
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RT @ExtripWorkgroup: @bobhoffmd @MarcGhannoum @ValeryLavergne @sgosselinmd @1darren1Dmr @Tom_Nolin @VijayanMD @DrDianeC @weddellite @cyates….
pubmed.ncbi.nlm.nih.gov
BAAs have different properties affecting their removal by ECTR. The EXTRIP workgroup assessed propranolol as non-dialyzable. Atenolol and sotalol were assessed as dialyzable in patients with kidney...
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RT @ExtripWorkgroup: @bobhoffmd @MarcGhannoum @ValeryLavergne @sgosselinmd @1darren1Dmr @Tom_Nolin @VijayanMD @DrDianeC @weddellite @cyates….
pubmed.ncbi.nlm.nih.gov
Both dialyzability and clinical data do not support a clinical benefit from ECTRs for CCB poisoning. The EXTRIP workgroup recommends against using extracorporeal methods to enhance the elimination of...
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RT @ExtripWorkgroup: @bobhoffmd @MarcGhannoum @ValeryLavergne @sgosselinmd @1darren1Dmr @Tom_Nolin @VijayanMD @DrDianeC @weddellite @cyates….
pubmed.ncbi.nlm.nih.gov
Isoniazid toxicity from self-poisoning or dosing errors remains common in regions of the world where tuberculosis is prevalent. Although the treatment of isoniazid poisoning is centered on supportive...
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RT @ExtripWorkgroup: @bobhoffmd @MarcGhannoum @ValeryLavergne @sgosselinmd @1darren1Dmr @Tom_Nolin @VijayanMD @DrDianeC @weddellite @cyates….
pubmed.ncbi.nlm.nih.gov
On the basis of our systematic review and analysis, the EXTRIP workgroup recommends against using extracorporeal methods to enhance elimination of these drugs in patients with severe chloroquine or...
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EXTRIP's lithium criteria were externally validated and compared to recently suggested Paris Criteria. Bottom line: "EXTRIP criteria outperforms the Paris criteria at identifying potentially ill patients who might benefit from haemodialysis."
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EXTRIP suggests against performing dialysis in addition to standard care in isoniazid poisoning. If B6 cannot be administered, we suggest performing dialysis only in seizures refractory to GABA agonists . Pharmacotherapy. 2021 Mar 4. doi: 10.1002/phar.2519. PMID: 33660266.
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