Alex LeNail
@AlexLeNail
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Computational Biology PhD student @MIT with Myriam Heiman and @JswLab
Cambridge, MA
Joined January 2010
RT @RichardHanania: Man comes to the US from Lebanon. Starts out delivering pizzas, becomes a Nobel winning neuroscientist. Trump freezes h….
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RT @SynBio1: Every synthetic biologist, every biochemist, when they dream, will sometimes hear a voice calling. A whisper on the wind, as i….
nature.com
Nature - A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible,...
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RT @internetarchive: 📚 Attention Readers & Researchers 📚. More than 500,000 books have been removed from our lending library due to the pub….
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I'm immensely grateful to the @PhRMAfoundation for supporting me, my journey, and my work. I hope our approach to enhancing neuronal resilience to aging & degeneration turns out to be an effective one.
#PhF24 awardee @AlexLeNail of @MIT is conducting research that aims to forestall the onset of #brain diseases by fortifying neurons' ability to maintain their health during #aging. Hear Alex's journey in the full interview: @mitbrainandcog @MITBiology
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I'm hopeful that instigating repair of aging-related molecular damage in neurons will prove to be an effective way to treat multiple neurodegenerative diseases. I'm very grateful for the support from Amaranth so we can find out whether that's the case.
This report is the months-long culmination of some of the brightest young leaders in the longevity field coming together to prioritize and detail the field’s top bottlenecks:.
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RT @samgoldman19: Protein structure prediction has been “neuralized,” but what about small molecule structure prediction from spectra? . Ex….
biorxiv.org
Metabolomic studies have succeeded in identifying small molecule metabolites that mediate cell signaling, competition, and disease pathology in part due to large-scale community efforts to measure...
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RT @NoamPrywes: Here at @SavageCatsOnly we are thrilled to present a review on rubisco. We focused on structure, mechanism, evolution and e….
arxiv.org
Carbon fixation is the process by which CO2 is converted from a gas into biomass. The Calvin Benson Bassham (CBB) cycle is the dominant carbon fixation pathway on earth, driving >99.5% of the ~120...
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RT @erika_alden_d: Biology should, can, and will be more like software engineering. The 2022 Bioautomation Challenge is going to kickstart….
alignbio.org
Reproducible. Scalable. Sharable. Improving research science with programmable experiments.
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RT @ChrisRackauckas: I am very happy to announce SciMLCon 2022. It's more than just a conference for #sciml @SciML_Org, it's also a start o….
discourse.julialang.org
We are pleased to announce a new conference in the Julia sphere, SciMLCon, focused on celebrating the advancements and applications of the SciML Open Source Software ecosystem. With that, the...
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RT @josephmreplogle: I'm thrilled to share our latest work performing genome-scale Perturb-seq screens to explore a remarkable breadth of q….
biorxiv.org
A central goal of genetics is to define the relationships between genotypes and phenotypes. High-content phenotypic screens such as Perturb-seq (pooled CRISPR-based screens with single-cell RNA-seq...
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How do you learn ODEs which describe timeseries data? (e.g. a chemical reaction network?).
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