By tweaking this #enzyme in only a handful of places we made it activated by K+ ions… some #proteins are remarkably engineerable! @BruningLab (1/3)

Merry Christmas from our favourite sticky nucleic acid binding protein. Great work from @KoningHeidar @CharlieBondXray and team! .@NAR_Open .Structural plasticity of the coiled–coil interactions in human SFPQ

#SAXSsnacks @ausynchrotron

Hello @ausynchrotron. It's been a while! Can't wait to shoot some proteins with some X-rays on Wednesday #bioSAXS

RT @PerthProteins: ‼️Reminder‼️. Only one week left for abstract submission for #PPG2024. Registrations are still open! (.

RT @PerthProteins: #PPG2024 is just around the corner and will be held at ECU (Joondalup) on 1 Nov 2024! . Registrations are open ( https://….

RT @ItaiYanai: Doing good science is 90% finding a science buddy to constantly talk to about the project.

Highlights:.•The shorter disordered part of SFPQ drives phase separation and nuclear condensate formation.•The long prion-like part of SFPQ attenuates phase separation and condensate formation.•This presents a mechanism for self-control of phase separation via multiple LCRs.

Describing the different effects that the disordered parts of #SFPQ have on it's ability to form #condensates inside and outside the cell. Big thanks to Mihwa Lee @CharlieBondXray @AFox_Perth @HymanLab @AnggonoLab members for your input 🙏 #phaseseparation

Thanks @CallumVerdonk for kicking off an interesting discussion on history and present state of science @PerthProteins #PPG2023

Some SAXy data on sticky SFPQ proteins from @KoningHeidar @PerthProteins #PPG2024

CRISPR, antiCRISPR, new bacterial immune systems, precision gene editors and Microbial dark matter! Very cool research coming out of the @gavinjknott lab! @PerthProteins #PPG2024

What a perfect weekend to head to Albany 👌 #PPG

RT @PerthProteins: The below 🧵attempts to display the final draft program for #PPG2023. There's still time for last minute registrations at….

Can't wait to hear all about the research happening in the @gavinjknott lab @PerthProteins #PPG2023. There's still time to sign up to join us in Albany!.

Australians, we need to feel the weight of this. How can we not weep?.

RT @ulurustatement: 💬 “I think it’s one of the only ways that we will be able to see tangible change in my lifetime, in my baby’s lifetime,….

Airlie McCoy full of quotable quotes; talking MR @IUCr2023. "It's hard to find things in the literature that didn't work"."The first rule of automation is to not automate in the same way as you do things manually"."Build better idiot-proof software and you build a better idiot"

Crystallography tour de force by @apthompson11 @IUCr2023 💎 ."The future of crystallography lies in throughput".

I ❤️ crystallography, and if you ❤️ medicine, molecules, materials or mobile phones, you should ❤️ crystallography too. Amazing public lecture by Prof Jennifer Martin @IUCr2023

Thank you @arc_gov_au for funding my #DECRA project #DE24! A huge thank you to my reviewers for your feedback and kind comments, and of course to my ever-so-supportive mentors @CharlieBondXray and @AFox_Perth. Can't wait to do more condensed protein experiments @SMS_UWA ! 👨‍🔬🧪🔬.