accardilab
@accardilab
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We study structure and function of ion channels, transporters and scramblases. #Biophysicists #Biochemists #Addictedtocoffee
New York
Joined September 2019
Thanks to @CrinaNimigean and @Shubhi2202 for involving us in this fun project!
Excited to share our most recent paper on how the beta2 subunit inactivates BK channels using the ball-and-chain mechanism! Congrats to @Shubhi2202, @lizdkim, and Alex and grateful to our collaborators: @SangyunLee16 and @accardilab! @WCMAnesthesia
https://t.co/3pud9cTSO4
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SGP congratulates Dr. Huanghe Yang on receiving the 2025 Paul F. Cranefield Award for his outstanding paper, “Niclosamide potentiates TMEM16A and induces vasoconstriction” https://t.co/Z21VWvCk0B
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SGP congratulates Dr. Man Si on receiving the 2025 Cranefield Postdoctoral Fellow Award for her outstanding paper, “Epilepsy-associated Kv1.1 channel subunits regulate intrinsic cardiac pacemaking in mice” https://t.co/x3nyfXiSKZ
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SGP congratulates Dr. Rachael Lucero on receiving the 2025 Cranefield Student Award for her outstanding paper, “Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family” https://t.co/e0gX7tSVmK
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Tickets to the 12th JGP-SGP Mixer are going fast! Join us in LA to connect with fellow SGP members. There is no charge to attend, but you must be an SGP member and register at https://t.co/hnDgu9j3IH. To join SGP, please visit https://t.co/oEpddRbd8X.
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Great to see Wandi Zhu, PhD on the list! Dr. Zhu recently joined the Department of Molecular Medicine & Therapeutics at @OhioStateMed. @OSUWexMed
JGP Editor-in-Chief @DavidAEisner provides an update at JGP as we welcome new Editorial Advisory Board members: Elisabetta Brunello, Kathy Engisch, Marcel P. Goldschen-Ohm @OhmMarcel, Christian Jorgensen, Godfrey Smith, and Wandi Zhu. https://t.co/9ZHrtVHIEn
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Congrats to @MDiverLab and team! Such a cool paper with a novel mechanism for a physiologically central transporter! Beautiful work! Transport and InsP8 activation mechanisms of the human inorganic phosphate exporter XPR1 | bioRxiv
biorxiv.org
Inorganic phosphate (Pi) has essential metabolic and structural roles in living organisms. The Pi exporter, XPR1/SLC53A1, is critical for maintaining cellular Pi homeostasis. When intercellular Pi is...
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✅ @Harraz_Lab has an open lab technician position ✅ Highly motivated individuals with relevant experience are encouraged to apply. https://t.co/ac0ZXzvaQb 📢 We explore brain blood flow, physiology and pathophysiology of ion channels. Learn more https://t.co/xKpn4iy0ct Plz RT
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ninds.nih.gov
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Congratulazioni Francesca!
Proud to announce Francesca Vallese @Frances84469032 joining @asrc_gc Structural Biology Initiative and @CCNYChem as a new Assistant Professor, bringing expertise in cryo-EM and biochemical studies of cytoskeletal complexes! Deets at https://t.co/QAelraBACl. Welcome, Francesca!
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The general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders, according to a team led by Dr. Crina Nimigean and Dr. Elizabeth Kim of @WCMAnesthesia. Full story: https://t.co/BJNC08dlov
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New insights into the activation and internalization of glutamate receptor mGluR from Levitz lab, now in @NatureComms The "rolling TMD interface" model is based on electrophysiology, cell imaging, FRET and cryoEM https://t.co/xLxSLooADT 🦸@Alexa_Strauss8 @albjglez @JoonLeePhD
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🚨Abstracts deadline is 1 week away: 1 August! Submit at https://t.co/4f6Vtsu7wR for🧳Travel Award and💬Short Talk consideration! The #sgp2024meeting will focus on cutting-edge research on the functional conservation and molecular evolution of membrane-related molecules, such as
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Postdoctoral position in computational biophysics, machine learning, and structural biology is open! Please see details in the attached.
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Congrats @lisi8810 !! Well deserved award!
SGP congratulates Dr. Lisandra Flores-Aldama @lisi8810, recipient of the Society's 2024 Excelsior Award! We look forward to Lisandra's talk at the meeting! We hope you join us. The abstract deadline for Short Talk and Travel Award consideration is 2 days away, 1 August. Submit at
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Thank you @CrinaNimigean for involving us in this exciting project! Was a lot of fun to work with everyone on the teams!
https://t.co/DcIHAbvebp Great work by Elizabeth Kim (@lizdkim) and Xiaoan Wu! Collaboration with teams of Peter Larsson (Linkoping University), Alessio Accardi (@accardilab) and Peter Goldstein @WeillCornell @WCMAnesthesia. Free link:
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Structures of channels in Open conformation are rare. Thrilled to share our latest manuscript.. Structural basis for hyperpolarization-dependent opening of human HCN1 channel
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Don’t miss this!
🚨Register for the 77th @sgpweb Meeting🚨, ⭐️"Molecular Evolution in the Membrane: Ion Channels, Transporters, and Receptors"⭐️ Want to be considered for a short talk? Submit your abstract by 🗓️1 August! For more info and to register, visit https://t.co/4f6VtsuFmp.
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@Nozomi_Ando’s research dives into the world of protein dynamics, aiming to elucidate protein function under allosteric interaction during catalysis & regulation. Listen to her Cohn Award lecture, "The structural biology of enzymes in motion." https://t.co/y4Xw1YHOi4
#DiscoverBMB
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