Emma West
@_emmarosewest
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Co-founder of Digital Biology
Boston, MA
Joined October 2011
What if you could image cells in fixed tissue sections, choose which ones to sequence 🔬, and then return to the same cells after NGS? Light-Seq⚡️🧬: high-res spatial sequencing of cells in fixed tissue for directly linking imaging + NGS + protein stains! https://t.co/2iNsr12vhA
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Very excited to announce Manifold's partnership with Roche to deliver the next generation of brain shuttled therapeutics for CNS diseases, using Manifold unique capabilties in AI + massively scaled in vivo measurment of drug molecules. This deal is the culmination of over 6
endpoints.news
Roche partners with Manifold Bio in $55M upfront deal for brain-penetrating drug development, with potential $2B in milestones. Companies to advance blood-brain barrier crossing proteins.
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Manifold and Roche partner for up to $2B There are lots of cool things about this deal. First off, obviously the science. Roche has been at the forefront of blood-brain barrier (BBB) delivery with really exciting early data around Trontinemab which opened this space up. And
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What you’re seeing at @ManifoldBio is what happens when two exponentials begin to resonate–the evolution of AI and the evolution of massively parallel molecular measurement and design. When we started Manifold Bio with @PierceOgdenJ , @geochurch , and @slofgren, we set out to do
The hardest problems in medicine will not be solved by incremental innovation. They will require a fundamentally new approach that grounds AI-driven design in large-scale data from living systems. Excited to announce our partnership with @Roche
https://t.co/GpLmyK7kdS
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We were thrilled to host Biotech in the Year 2048: From Signal to Solution in Boston! It was an incredible day full of conversations and ideas, from panels on measuring novel biomarkers and turning data into drugs, to our quick-fire pitch competition showcasing some of biotech’s
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We’re excited to share a new multi-year collaboration with @TakedaPharma, building on the success of our first engagement. Under the agreement, Nabla will receive double-digit millions in upfront and research payments and is eligible for success-based payments exceeding $1
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📢 Biotech in the Year 2048 is happening next week in Boston! On October 14th, we’re bringing together founders, investors, and industry leaders to time-travel into the future and explore the technologies and data that will shape the next two decades of biotech. 💡 Hear from
partiful.com
Join us in Boston on Thursday, October 2 for Biotech in the Year 2048: From Signal to Solution — a forum on the technologies and data shaping biotech’s next two decades. The afternoon will feature...
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AI is not on track to eradicate disease in our lifetime. Scientists need to generate more data, but they’re physically limited by how fast they can work. That’s why we’re launching Medra: Physical AI in the lab, doing and optimizing real experiments. Thread👇
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𝐀𝐈 𝐱 𝐁𝐢𝐨 𝐒𝐮𝐦𝐦𝐢𝐭: @ManifoldBio Co-Founder & CEO @glebkuz describes the company’s ability to screen proteins it has designed in silico at scale in vivo.
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a core tension in applying "virtual cell" models to therapeutic development is the mismatch between the scale at which we measure biology and the scale at which we intervene. we often measure at the cell level (eg single-cell RNA-seq), but we treat at the tissue or organ level
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𝐀𝐈 𝐱 𝐁𝐢𝐨 𝐒𝐮𝐦𝐦𝐢𝐭: Digital Biology Co-Founder & CEO @_emmarosewest describes how the AI field is moving on from modeling protein folding to a next phase of better understanding binding function.
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Digital Bio unlocked spatial NGS in FFPE patient tissues, at scale. Check us out!
digit.bio
Discover Digital Biology’s revolutionary M×P Platform, integrating high-resolution imaging, next-generation sequencing, and AI automation to optimize drug discovery and advance biological medicine.
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@pratik_katte @SrikarVaradaraj @danesonance @sciqst see our paper for more on DNA photolithography https://t.co/2iNsr12vhA More to come on Digital Bio soon - stay tuned! We’re coming out of stealth in 2025, with supercharged measurements to design and screen biomedicines ⚡️🧬
nature.com
Nature Methods - Light-Seq uses light-directed DNA barcoding in fixed cells and tissues for multiplexed spatial indexing and subsequent next generation sequencing. This approach blends spatial and...
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Happy holidays from the Digital Bio team! We've hijacked photolithography -used in printing silicon chips- to print DNA. This is our logo printed in DNA on a biological tissue. Much more to come from us in the new year, using this to fuel an engine for biological medicines 🚀
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Thrilled to see Digital Bio's fearless leader in @techreview's top innovators list! Congratulations @jykishi, so well deserved!!
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Congrats to this amazing team!!!
Excited to share @nablabio is partnering with 3 of the world’s largest pharma cos to use integrated AI and wet-lab tech to design antibodies against challenging disease targets. Thrilled to also add @radicalvcfund who led our $26M Series A to the family!
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Not everyone who dies gets to come back and tell their story, but thankfully Freddy did. A reminder to hold the people you love a little closer tonight, that medicine and health are the greatest gifts, and that at the end of the day, we're all patients. https://t.co/T8rds0XuBP
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Nothing like the team of optical experts @ Digital Biology as viewing partners for the eclipse
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Calling all mol bio experts to build the future of precision medicine with us. We're unlocking better in vivo optimization functions for next-gen therapies, deployed at scale, at the intersection of cutting-edge molecular tech, automation, and engineering
job-boards.greenhouse.io
Digital Biology is pioneering a discovery engine for multifunctional biologics, powered by breakthrough measurement technology. Our platform leverages DNA photolithography to print molecular GPS...
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Please RT! Work directly with me @GordianBio as our Scientific Chief of Staff & be part of everything it takes to run a growing biotech. You'll have wide responsibilities, owning projects and culture improvements, organizing our teamwork, and helping me set the company strategy.
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