What if you could image cells in fixed tissue sections, choose which ones to sequence 🔬, and then return to the same cells after NGS?.Light-Seq⚡️🧬: high-res spatial sequencing of cells in fixed tissue for directly linking imaging + NGS + protein stains!.

Digital Bio is hiring. JOIN US!

@pratik_katte @SrikarVaradaraj @danesonance @sciqst see our paper for more on DNA photolithography . More to come on Digital Bio soon - stay tuned! We’re coming out of stealth in 2025, with supercharged measurements to design and screen biomedicines ⚡️🧬.

Happy holidays from the Digital Bio team! . We've hijacked photolithography -used in printing silicon chips- to print DNA. This is our logo printed in DNA on a biological tissue. Much more to come from us in the new year, using this to fuel an engine for biological medicines 🚀

Thrilled to see Digital Bio's fearless leader in @techreview's top innovators list! Congratulations @jykishi, so well deserved!!.

Congrats to this amazing team!!!.

Not everyone who dies gets to come back and tell their story, but thankfully Freddy did. A reminder to hold the people you love a little closer tonight, that medicine and health are the greatest gifts, and that at the end of the day, we're all patients.

Nothing like the team of optical experts @ Digital Biology as viewing partners for the eclipse

Calling all mol bio experts to build the future of precision medicine with us. We're unlocking better in vivo optimization functions for next-gen therapies, deployed at scale, at the intersection of cutting-edge molecular tech, automation, and engineering

RT @MartinBJensen: Please RT!.Work directly with me @GordianBio as our Scientific Chief of Staff & be part of everything it takes to run a….

Nice translatable approach for IDing new rejuvenation factors for primary human cells from @amplesa and team. Super exciting to see potent single-factor effects for wound repair - the old mouse skin in Fig 4e is truly wild.

RT @mfgrp: Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent immune response a….

Extremely grateful to @Forbes for recognizing our work at Digital Biology on the Forbes 30 Under 30 Healthcare 2024 list. Incredible to build the future of frontier tech in medicine alongside my amazing co-founders @jykishi and Sylvain Lapan and our team!

RT @ron_alfa: This week in AI: Have LLMs achieved AGI and become too powerful for humanity? . This week in Biotech: Should we stop building….

RT @ElliotHershberg: Medicine's Endgame 🧬. What is a medicine? For most of us, medicines are small pills in white bottles with cotton tops.….

(4/4) Sampling the space of engineering possibilities with functional readouts of cell interactions in humanized systems is the path to making truly programmable protein delivery machines 🔬🧬🧫.

(3/4) Screening of engineered cell interactions w/in tissue microenvironments will blow open this future of biologics. Engineering cells is virtually limitless, but parallelized functional screening remains nearly impossible. .

(2/4) Shuttling foot soldiers (therapeutic proteins) in an armored car (engineered plasma cells) with other tactile passengers to get them where they need to go, safely. Oh, and pumping out 10,000 soldiers/second, for years! Amazing work from Rich James:

(1/4) There are >200 approved protein therapeutics. Major limitations are the need to constantly re-dose and high potential for unhinged immune responses. Engineered plasma cells (ePCs) are among the most exciting modalities in therapeutics today 🧬🦠.

RT @sethbannon: In Boston for the Digital Biology lab opening party. Something special cooking here. @jykishi and @_emmarosewest are buildi….

RT @ElliotHershberg: Do you want to work at the forefront of molecular engineering? 🧬. Want to work with *great* people? Love cutting edge….