Zechner lab
@zechnerlab
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Theory lab at SISSA / Trieste. Interested in stochastic processes in biology & biophysics. @zechnerlab.bsky.social
Dresden, Germany
Joined March 2017
Exciting news! As of today, our group is part of SISSA in Trieste. Big THANK YOU to all current and past group members, collaborators and mentors and to @mpicbg for hosting us for 8 amazing years! If you are interested in joining us in Trieste, please get in touch! @Sissaschool
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Very happy to share the first article from my postdoc work in the Tomancak lab! https://t.co/0gmwblw1Wb. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
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Code for the numerical examples shown in the paper is also available: https://t.co/lV0YRxnu0V
github.com
Contribute to zechnerlab/LPAC development by creating an account on GitHub.
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The new method is integrated into our symbolic moment generator Compartor, which is available on GitHub: https://t.co/m8a8brD7Sa
github.com
Contribute to zechnerlab/Compartor development by creating an account on GitHub.
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Tommaso's paper on approximating moments of stochastic multiscale models is now out in Math Biosci! Fantastic job by @churli ! @csbdresden @mpicbg
https://t.co/E4parEiFGI
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This is now up @BiophysJ! Getting lipid signaling kinetic parameters from single-cell data with @MLennartz1 @PavelBarahtjan @looneycoons11 @JManuel9112 @zechnerlab @nadlerlab @MMSchuhmacher 😀😊 Read here! https://t.co/TBA2tMA424
Together with the @zechnerlab we have pushed live-cell quantitative lipid biochemistry to the single cell level. It works - but some lipids are weird. 🤓 Great effort by shared 1st authors @davidtgonzales1 and @MMSchuhmacher. Let us know what you think!
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Cover image @ChemSystemsChem featuring our synthetic cell communities https://t.co/xHP2J8USM9 😀 @DoraTang5 @zechnerlab @mpicbg
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Two great talks from Tarun Mascarenhas and Anne-Lena Moor from Zechner lab on information transfer during @centuri_ls conference in Cargese. Very interesting. 😊
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Its out! We integrate Cell‐Free Quorum Sensing Gene Circuits into Droplet Interface Bilayers. A great platform for bio-inspired bidirectional communication. Beautiful work @gonzalesdavid in collaboration with @zechnerlab! See it here.... https://t.co/4f8tutN6Li
chemistry-europe.onlinelibrary.wiley.com
Building communicating synthetic cells using droplet interface bilayers encapsulating cell-free expression systems with quorum sensing gene circuits.
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Officially out now @EMBOPress with a beautiful cover by @NerliElisa! Enjoy... https://t.co/0Z2i6G1vrk
embopress.org
image image Stereotypic organ development depends on the correct timing and appropriate acquisition of cell fate by the differentiating progenitor cells. Here, comprehensive lineage analysis in the...
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How do distant DNA loci come into contact to activate genes? Our paper combining live imaging 🔬& polymer physics 🧬 to answer this is out in @ScienceMagazine! We show how chromosome packing & diffusion determine pairwise dynamics & transcription 👉 https://t.co/8mHc7ioOwu 1/n
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Very proud to share that former group member @LorenzoDuso was awarded the Otto-Hahn Medal for his outstanding PhD thesis @csbdresden @mpicbg Many congratulations for this exceptional achievement! Image: © David Ausserhofer / Max-Planck-Gesellschaft
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Congrats David!!
Our preprint on building a bottom-up synthetic multicellular community is up! 😄 https://t.co/qjwnP1Vkrg See how we use cell-free expression of quorum sensing gene circuits in DIBs to make synthetic cells that communicate and have feedback loops! @DoraTang5 @zechnerlab @mpicbg
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Together with the @zechnerlab we have pushed live-cell quantitative lipid biochemistry to the single cell level. It works - but some lipids are weird. 🤓 Great effort by shared 1st authors @davidtgonzales1 and @MMSchuhmacher. Let us know what you think!
biorxiv.org
Studying the role of molecularly distinct lipid species in cell signaling remains challenging due to a scarcity of methods for performing quantitative lipid biochemistry in living cells. We have...
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Excited to share Anne's new paper in Phys Rev Res, presenting a method to quantify information transmission (-rates) in biochemical networks. Congrats!! @csbdresden @mpicbg
journals.aps.org
We develop numerical and analytical approaches to calculate mutual information between complete paths of two molecular components embedded into a larger reaction network. In particular, we focus on a...
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Open PhD position to work with me on the Stochastic dynamics and thermodynamics of living systems @KCL_Physics @KingsCollegeLon to start in Oct ‘23
findaphd.com
PhD Project - Stochastic Dynamics and Thermodynamics of Living Systems. at King’s College London, listed on FindAPhD.com
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Thanks @Dmichiel1 @wendy_bickmore for highlighting in @MolecularCell
https://t.co/mOmzM2O8nX our recent work https://t.co/WJta8hUSmT visualizing a TAD-forming CTCF/cohesin loop in live cells and showing these structures to be dynamic, rare, and largely partially extruded.
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Next up @davidtgonzales1!! Wonderful example of a multidisciplinary PhD project, combining both experiment and theory. Many congratulations to your graduation David!! @tanglab @mpicbg @csbdresden @imprs_mpicbg
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Huge congratulations to @FOltsch for his outstanding PhD defense last week! Many thanks for all the great work & fun and best of luck for your future adventures! @imprs_mpicbg @csbdresden @mpicbg
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A thing to copy is @mpicbg tutorial with PhD students and ECRs before a seminar. I had a great time with these outstanding scientists. Many thanks to @zechnerlab for the invitation and discussions. Near-zero carbon footprint and no jetlag added bonus.
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