Haojun Yang
@Yang_Haojun_01
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Joined August 2024
Could a ketogenic diet be the key to fighting pancreatic cancer? @UCSFcmp researchers recently found that a cancer drug, eFT508, blocks fat metabolism. By pairing it with a fat-only diet they were able to starve tumors in mice. @RuggeroDavide
ucsf.edu
A breakthrough study shows how a ketogenic diet alters human metabolism and makes a particular pancreatic cancer drug effective by starving tumors of fat that they feed on to grow.
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How does fasting remodel the body at a molecular level? Can you starve the aggressive pancreatic tumor using a specific diet? Our work reveals that a specific translational control governs this regulation.
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I'm super excited that our work @Ruggero lab on translational control during fasting and tumorigenesis upon diet therapy is out today at Nature.
nature.com
Nature - During fasting, hepatocytes selectively remodel the translatome while global translation is downregulated, showing a new signalling property of fatty acids and that, on a ketogenic diet,...
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