Haihua Xiao@ICCAS
@XiaoHaihua
Followers
2K
Following
3K
Media
62
Statuses
865
Biomaterials,Nanomedicine,Metals in Medicine; Former Postdoc@Massachusetts Institute of Technology and University of Notre Dame. Email:[email protected].
Beijing, China
Joined November 2016
@XiaoHaihua A recent work from my lab, please share with your friends.
nature.com
Nature Immunology - Given associations between colitis and myelodysplastic syndrome (in which nucleophosmin 1 is often mutated), the authors here look at the contribution of nucleophosmin 1 to...
0
1
4
Congratulations to Dongsheng Tang for his fourth publication on delivery of dinulcear Iridium(III) complexes at Advanced Materials .See:
advanced.onlinelibrary.wiley.com
An ultrasound-triggered, near-infrared fluorescent dinuclear iridium(III) nanoparticle, NanoIr, is reported to precisely and spatiotemporally generate reactive oxygen species for immunogenic sonody...
3
5
42
Congratulations to my Phd candidate Dongsheng Tang for his fourth publication at Nature communications. see:
nature.com
Nature Communications - The application of synthetic polymeric nanoparticles for cancer therapy is limited by its biosafety and targeting ability. Here the authors report cationic nanoparticles...
1
3
48
Happy to share our paper “Polymer-based delivery systems with metal complexes as contrast agents for medical imaging” has been published in top journal “Coordination Chemistry Reviews” @ElsevierConnect @XiaoHaihua full text here
0
1
11
0
1
33
Check out our paper in @Biomaterials_ on the Encapsulation of Chemotherapeutic Iridium Complexes in Nanoparticles for NIR Photoactivated Chemotherapy. Congrats to @NMontesdeoca_ ! Wonderful collaboration with @XiaoHaihua ! @ChemieBiochemie @ruhrunibochum
https://t.co/1YoGWRf0Iy
18
15
119
Congratulations to my joint student Peng Xie for his publication Pt(IV) with Perfluorocarbon Chainsfor Highly Effective Antitumor Chemoimmunotherapy".See: https://t.co/Y0J8u4zBxt
pubs.acs.org
Tumor metastases and reoccurrence are considered the leading causes of cancer-associated deaths. As an emerging therapeutic method, increasing research efforts have been devoted to immunogenic cell...
1
6
45
Congratulations to Dr.Yingjie Yu, who is a young professor at Beijing University of Chemical Technology right now.
0
0
1
The polyplatin of hands-holding Pt(IV) prodrugs with NIR-II fluorophores for real-time drug tracking and treatment feedback!!! See our recent publication at Advanced Materials. https://t.co/7NKbqBrDrN
advanced.onlinelibrary.wiley.com
For real-time drug tracking with accurate drug metabolism information, a near infrared-II (NIR-II) fluorophore is conjugated with Pt(IV) prodrug via a covalent bond to form PolyplatinDT. PolymerDT...
6
8
41
This review provides insights into the application of various #omics studies to understand the mechanistic action of #nanodrugs, highlighting their advantages and outlining future directions in nanomedomics. @Johannes_Karges @ruhrunibochum Read here 👉 https://t.co/ObldSUTOVz
0
5
19
Congratulations to my joint student on his first publication "Platinum Prodrug Nanoparticles with COX‐2 Inhibition Amplify Pyroptosis for Enhanced Chemotherapy and Immune Activation of Pancreatic Cancer".See: https://t.co/jvbiuimGV4
advanced.onlinelibrary.wiley.com
An amphiphilic polymer (PHDT-Pt-In) incorporating a Pt(IV) prodrug and indomethacin (In) is developed here. PHDT-Pt-In can further self-assemble to form Pt-In NP, which overcomes the chemoresistance...
0
5
25
Congratulations to Ganghao Liang for the new concept of "Nanomedomics" in nanomedicine to advocate the integration of omics with nanomedicine. See:
pubs.acs.org
Nanomaterials have attractive physicochemical properties. A variety of nanomaterials such as inorganic, lipid, polymers, and protein nanoparticles have been widely developed for nanomedicine via...
0
3
10
Congratulations to Yan Xu for her first publication on Advanced Functional Materials. The design of new sonodynamic materials for anti-bacteria. See: https://t.co/4eAbpBO0aS
advanced.onlinelibrary.wiley.com
This study presents new 4,4-difluoro-4-boron-3a,4-diaza-indandiene (BODIPY)-based nanomaterial BODN-nanoparticle (NP), which is proposed as an efficient sonodynamic that kills both Gram-negative and...
0
11
47
Our paper on the design of trisulfide polymer for delivering platinum(IV) prodrugs for overcoming ovarian cancer resistance. see: https://t.co/zbaGDGXb5u
pubs.acs.org
The clinical application of cisplatin (CisPt) is limited by its dose-dependent toxicity. To overcome this, we developed reduction-responsive nanoparticles (NP(3S)s) for the targeted delivery of a...
2
10
47
Our work on using phasor-FLIM to track supramolecular assembly and endosome fusion hybrids in cells is out! Congratulations to @_YongRen_ @zhou_zhixuan @WeilTanja and the @mpi_polymer collaborators for their excellent work. Special thanks to the EM team! https://t.co/1rp9Mmqeno
pubs.acs.org
The complex dynamics and transience of assembly pathways in living systems complicate the understanding of these molecular to nanoscale processes. Current technologies are unable to track the...
2
13
67
Check out our review article in @acsnano on the multiomic analysis of nanomedicines. Great collaboration with @XiaoHaihua. @ChemieBiochemie @ruhrunibochum. https://t.co/oEPzCET6Se
13
6
76
Curious about Immunogenic Cell Death (#ICD) and its potential in tumor treatment? Click the🔗to watch a review on ICD Inducing Metal Complexes for Cancer Therapy by @Johannes_Karges and @XiaoHaihua, presented by E.Matnurov https://t.co/YSwWQUTFYL
#CancerResearch #TumorTreatment
1
5
17
We report a dual-lock approach to embed small molecule drugs in cyclic structure, for selective & traceless release in cancer cells. Congrats to @DominikSchauen1, @Seah_Ling & our collaborators @VijayChudasama_ @J_A_S_Coelho! https://t.co/ItO71CIEwi
onlinelibrary.wiley.com
A dual-locked approach to embed a small-molecule drug in a cyclic structure to control bioactivity is described, with the possibility to introduce cell-targeting entities. Selective and traceless...
3
9
66