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Armin Töpfer Profile
Armin Töpfer

@XLR

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Following
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Statuses
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Husband. Parent. Dr sc @ETH. Bioinformagician. Father of @PacBio HiFi. C++ Purist. Geek. Digital Artist. Electronic music. Speaks in memes. Opinions are my own!

Germany
Joined November 2008
Don't wanna be here? Send us removal request.
@XLR
Armin Töpfer
11 days
When a candidate's CV matches the job description too well
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@XLR
Armin Töpfer
12 days
I should vibe code a cluely detector.
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@XLR
Armin Töpfer
12 days
Since it's hiring season, the first question I ask, after a five minute overview of the team, the responsibilities, and myself: Why do you want to join [COMPANY]?
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@XLR
Armin Töpfer
12 days
I've used a lot of GPT-5 Pro and Opus 4.1 to think deeply about how to make HiFi generation faster or better. Everything it told me, I've already tried.
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@XLR
Armin Töpfer
13 days
Being forced to read Python and Go slop.
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@XLR
Armin Töpfer
16 days
Unpopular approach to learning C++ During my MSc, I had a great tutor, who taught me binary auditing and reverse engineering using IDA Pro. He challenged us to understand the assembly code, find ways to exploit it and write the exploit, or implement keygens. Thankful for that!
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@XLR
Armin Töpfer
18 days
No update from my side
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@XLR
Armin Töpfer
29 days
Thanks to ChatGPT, most of your CVs look the same and make it much easier to filter.
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@XLR
Armin Töpfer
30 days
🚀 We at @PacBio are hiring! Looking for a C++ & CUDA Software Engineer (US/EU) to help shape the future of long-read SMRT sequencing. Join a team with high coding standards that thrives on solving tough problems from first principles. Apply 👉
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@XLR
Armin Töpfer
1 month
Today was a good day. Sonnet 4.5 and installed new GPU. Still waiting for the case to arrive.
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@XLR
Armin Töpfer
1 month
You are tuning your HiFi CUDA kernels by hand?
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@gary_miklos
Gary
1 month
Ok, since I need real feedback to keep working on my CLI app, I’m giving away FREE lifetime licenses to anyone who reposts this tweet.
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@XLR
Armin Töpfer
1 month
If the LinkedIn link on your CV results in a 404 and your linked GitHub profile has no public repos, do you even care?
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@XLR
Armin Töpfer
1 month
It's this season again, I'm going through CVs. If you claim to be detail oriented, but name your CV `Armin_Toepfer_Formatted_Resume (1).docx` then it speaks for itself more than the content. And for Christ's sake, do not send .docx! Only PDF.
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@XLR
Armin Töpfer
1 month
Torn between touching grass and cooking. BBQ time.
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@XLR
Armin Töpfer
1 month
Trigger-happy as usual @cursor_ai
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@XLR
Armin Töpfer
1 month
The urge to use those new models for some serious bioinformatics
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@XLR
Armin Töpfer
1 month
Newest low: I gave Claude Code the compile line to reproduce errors. It executes the line, patches the code and then claims it's done. I ask it to retry, it refuses to run the same command again and wants to check the next file. Gaslighting...
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@XLR
Armin Töpfer
1 month
I'm giving up on code-supernova for now. It also bloats up the context window insanely fast.
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