Vivek Mutalik
@vivek_mutalik
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Phylogeny-agnostic strain-level prediction of phage-host interactions from genomes https://t.co/5Yli2jLvSc
#biorxiv_micrbio
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This is the first of a powerful set of work from this amazing team! I am extremely grateful to work with these amazing young scientists-@AveryNoonan and @LucasMoriniere, my long time colleague and friend @vivek_mutalik and the EDGE and Phage Foundry teams. This group is on fire.
Posting here after a year to share: 📣 New preprint from https://t.co/tVwZIrsnTc team 📣🎊🎉 We developed a solid machine learning framework & to predict strain-level phage-host interactions across diverse bacterial genera from genome sequences alone. https://t.co/k1mRum70FP
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Amazingly our Model-guided cocktail design achieved 80.7-97.0% strain coverage w 5 phages.🎉 This platform enables rational phage therapy design & precision microbiome engineering with diverse applications in clinical, agricultural, and industrial contexts.
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Avery Optimized 13.2 million training runs across five datasets (128,357 interactions, 1,058 strains, 560 phages), great performance while eliminating phylogenetic constraints. & Lucas led all experimental validations!!
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This work, sets up an example of how we should do rigorous AI/ML work in phage biology and therapy field. @AveryNoonan from the @AdamArkinLab led this massive effort, with support from @LucasMoriniere
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Posting here after a year to share: 📣 New preprint from https://t.co/tVwZIrsnTc team 📣🎊🎉 We developed a solid machine learning framework & to predict strain-level phage-host interactions across diverse bacterial genera from genome sequences alone. https://t.co/k1mRum70FP
biorxiv.org
Bacteriophages offer promising alternatives to antibiotics for treating drug-resistant infections and engineering microbiomes, but applications are limited by inability to select phages infecting...
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I have moved away from this site. You can find me in Blue Sky! with a lot of prayers for this country and world. 🙏🏽
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I am taking a break. Good bye for a while ❤️🩹❤️🩹🧘♂️ take care of your ppl
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From the interiors of Germany, watching the US elections from a far, is like painful & unending feeling of loss. But spring will come, hope will be restored and trees will have fresh new leaves.
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Be gentle with yourselves, your family, friends and colleagues. This is going to hurt a lot. ❤️❤️
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Per the exit poll, a majority of white women voted for Trump. Again.
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Whatever the final outcome, the fact that Trump—a convicted felon, adjudicated rapist, pathological liar, virulent bigot and utterly reckless manager who kowtows to Putin and despises democracy— is this close to regaining the White House is deeply disturbing.
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Congratulations, Media. It looks like you succeeded in getting Trump reelected. You made excuses for him. You refused to cover the batshit crazy things he said and did. You sanewashed him at every turn. Looks like you got what you wanted.
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It took several days to count every ballot in 2020, and it’s very likely we won’t know the outcome tonight either. So please keep a few things in mind as you make your voice heard today: – Thousands of election workers around the country are working hard today. Respect them.
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