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Niclosamide, a medication for tapeworm infections, may help reduce nasal symptoms in ANCA-associated vasculitis patients, an analysis found. https://t.co/psYE918RFP

Day 2 Breakfast Session #vasculitis26 Prof John Stone - lots of B cells in IgG4-RD. He's posing the question: How much does IgG4-RD resemble AAV?

Susac syndrome 📝 An autoimmune microangiopathy mimicking a CNS vasculitis. 🔺Triad: encephalopathy, hearing loss, & retinal artery occlusion 🧠 MRI: shows corpus callosum lesions: ice pick/snowball ➡️ Mimic & not a vasculitis 💊 GC, IVIg, MMF, RTX #MedTwitter #Rheumatology

🩸🔥 JAK inhibitors as salvage therapy in refractory #TakayasuArteritis Multicentre BIOTAK registry (n=20): ✅ 50% achieved complete response at 6 months ⬇️ NIH score, CRP & steroid dose significantly reduced 🔁 24-month relapse rate: 18% ⚠️ Acceptable safety in heavily

Early combination therapy with tacrolimus, prednisolone and nintedanib significantly improves pulmonary function in previously untreated patients with progressive pulmonary fibrosis. The regimen was well tolerated, with manageable adverse effects.  https://t.co/bTmb6oYsYg

A recent European multicentre study on interstitial lung disease in #ANCA-associated #vasculitis (AAV-ILD) and isolated ANCA-positive ILD (ANCA-ILD) underscores that #lung #fibrosis severity is a dominant driver of poor prognosis (including respiratory failure and #mortality) in

🔬 New post-hoc analysis from the REALISTIC trial (n=930) examines whether high rheumatoid factor levels affect certolizumab pegol response in RA patients 📊 Patients with high and low RF levels showed similar clinical responses to CZP treatment, regardless of prior TNFi failure

VEXAS syndrome is a newly discovered multisystemic disease affecting most organs. A new Review provides a comprehensive overview of VEXAS syndrome, including the disease's discovery, diagnosis, and treatment: https://t.co/pZSkkGPbGJ

🩸 HES (Hypereosinophilic Syndrome) — Must-Know Points • Define: AEC ≥1.5×10⁹/L (×2) + organ damage • Biggest gap → Delayed diagnosis = preventable morbidity • First rule: Exclude secondary causes (parasites, drugs/DRESS, allergy, cancer) • Classify fast: 👉 Reactive 👉

En 2021, @EsSalud inauguró tomógrafos presentados como modernos, para 11 mil pruebas al mes. Hoy la Contraloría detecta que el del Hospital Almenara no opera como debería: elevó el riesgo de errores y generó S/ 6,1 millones de perjuicio. 5 funcionarios con responsabilidad penal🧵

🧪 Valganciclovir in anti-MDA5+ DM 👉🏼CMV infection is common in MDA5+ DM and affects outcomes 👉🏼Valganciclovir prophylaxis prevented CMV infections in treated patients vs controls (p=0.032) 👉🏼No major valganciclovir-related lab abnormalities observed https://t.co/ekKVLcwZB7

Our group has its own X account @GEAS_Peru, please, follow us! #AlmenaraLupusCohort #AlmenaraVasculitisCohort #AlmenaraRACohort

🆕paper: ­⬆️prednisone dose is associated with ⬇️ HRQoL ⬆️ fatigue & ⬆️ patient-reported disease activity. Project lead by @Asinghrheum #AlmenaraLupusCohort published in @jrheum https://t.co/jeUOu2P3u0

🔬 A study of 402 patients with ANCA-associated vasculitis examined whether ANCA antibody type (anti-PR3 vs anti-MPO) influences major adverse cardiovascular event (MACE) risk. 📊 Anti-MPO patients had higher MACE rates (33.1 vs 21.4 per 1,000 patient-years). Anti-PR3 specificity

🔬 Nuevo estudio multicéntrico en aortitis asociada a ACG🕵🏻TCZ SC 💉vs IV🩸 📈La vía sc mostró una ligera mayor tasa de remisión EULAR a los 24 meses. 🩻Remisión por imagen y control inflamatorio similares. 📉Importante efecto ahorrador de glucocorticoides en ambos grupos.

#VEXAS syndrome is linked to a nearly doubled overall #cancer risk compared with matched inflammatory disease controls (relative risk [RR] = 1.93, 95% CI 1.03–3.60, p = 0.036), including both hematologic and non-hematologic malignancies, as demonstrated by an analysis of data

Rituximab is at least as effective as cyclophosphamide in inducing remission in people with ANCA-associated vasculitis (AAV), a study found. https://t.co/8hb6I8dkP6

🚨Official guidelines for diagnosing and treating short #telomere syndrome, better known as Telomere Biology Disorders (TBDs), in lung disease and transplantation 🚨 International Society for Heart and Lung Transplantation 🫁🧬 #TBD #FPF #ILD #LungTransplantation #EarlyReferral👇

7 ideas about mycophenolate that every rheumatologist should know.👇 Concept 1: What we prescribe is not the active drug We prescribe MMF MMF → (in stomach) → MPA (active drug) Only MPA suppresses immunity. If this step is inefficient → drug effect falls. Concept 2:

Diffuse Alveolar Hemorrhage in Rheumatic Disease A retrospective, cross-sectional, single-center study of adult rheumatic disease patients with diffuse alveolar hemorrhage (DAH), demonstrates a high proportion have coexistent pulmonary infection and significant mortality risk.