Vasudevan Lab
@VasuLabUCSF
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Cancer signaling, (single cell) genomics, and functional genetics, with an emphasis on better diagnostic tests and treatments for neurofibromatosis.
San Francisco
Joined October 2022
Delighted to host the first annual @VasuLabUCSF holiday party - grateful to work with these people every day.
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Excellent time giving grand rounds last week @UMRogelCancer with old friends @gouthamnarla and new ones @castro2355_mg @UCSFCancer @NeurosurgUCSF
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Happy 4th of July - to celebrate, we asked if there is meaningful heterogeneity within somatic NF1 mutant glioblastomas? We think so https://t.co/LWwT0hcY2T As always, appreciate everyone that made this work possible @NeurosurgUCSF @UCSFCancer @ntapresearch @ChildrensTumor
biorxiv.org
NF1 is recurrently mutated in glioblastoma yet the molecular landscape and efficacy of targeted therapies remain unclear. Here, we combine bulk and single cell genomics of human somatic NF1 mutant,...
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A delightful time catching up with 10 of NTAP’s 18 Francis S. Collins Scholars & their mentors while in Brussels @ChildrensTumor. Thank you all for your dedication to moving the needle in NF1 research! #NFCON24 #endNF
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Sunrise-ish run through brussels - enjoying every part of the annual @ChildrensTumor meeting #nfcon24 with friends from @NeurosurgUCSF @ntapresearch
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Excited that our DoD New Investigator Award ( https://t.co/lX54TSeRJu) is officially funded - thanks to everyone that helped make this happen @CDMRP @domespo @simanshu and time to get to work!
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A pleasure to review the therapeutic landscape for NF-1 with my future colleague @bnamd87
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Additionally, in a study led by @VasuLabUCSF & @LabRaleigh, researchers demonstrate how NF-1 mutant Schwann cell tumors undergo malignant transformation, identifying new potential strategies against treatment resistance: https://t.co/O3NAcgFWGq
@UCSFCancer #neurofibromatosis
nature.com
Nature Communications - The molecular mechanisms underlying malignant transformation of the Schwann lineage in Schwann cell tumours remain to be explored. Here, the authors suggest that NF2...
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New featured image on our homepage! https://t.co/q0mdqcGp64 3 papers on schwannomas, tumors of the nervous system derived from Schwann cells @VasuLabUCSF @LabRaleigh @sjohnliu
#CancerResearch @NatResCancer
https://t.co/VrOAa1FWVQ
https://t.co/jHOddAQaKR
https://t.co/Gdu8UofjTG
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Very proud of @LexiHaugh for her analysis of targeted DNA sequencing in cutaneous melanoma: https://t.co/1Ns9QeEl9L
@ad1600
biorxiv.org
Importance Cutaneous melanoma (CM) can be molecularly classified into four groups: BRAF mutant, NRAS mutant, NF1 loss, and triple wild type (TWT) tumors lacking any of these three alterations. In the...
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Delighted to share that our work looking at functional interactions between neurofibromatosis tumor suppressors is officially accepted:
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Looking forward to #SNO2023 presentation by #FrancisSCollinsScholar @VasuLabUCSF presenting innovative approaches to targeting NF1 loss in nervous system tumors @NeuroOnc
@NTAPresearch @HopkinsMedicine #NF
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Our manuscript investigating bulk and single cell genomics of melanoma brain metastases is now online! Many thanks to everyone that made this work possible
jamanetwork.com
This cohort study evaluates how bulk and single-cell genomic features of melanoma brain metastases are associated with clinical outcome and treatment response.
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So pleased to see our work in @NatureComms, led by @SkakodubAnna, @hswalch, and @KathrynTringale, with @nikolausschultz, describing the genomics and clinical outcomes of a large set of patients with NSCLC brain metastasis. @MSKCancerCenter @MSK_RadOnc
https://t.co/4Dm0Y1WVpf
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Big congratulations to @LexiHaugh on her ASCO YIA! Excited to make some progress on (NF1 mutant) metastatic melanoma
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The Vasudevan Lab makes its first twitter post: Excited to share our preprint looking at functional interactions between NF tumor suppressors
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