VaD Matrix
@VaD_Matrix
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Consortium of researchers from Edinburgh, Glasgow, Manchester, Oxford & Cambridge investigating #extracellularmatrix defects in #SVD #dementia #stroke
United Kingdom
Joined September 2018
Our consortium is ecstatic to announce the launch of our website! Visit us at to find out all about our research on #NeuroGlioVascularUnit #MatrixBiology in #stroke & #dementia & the faces behind it @TheBHF @TheStrokeAssoc @alzheimerssoc @ARUKnews @BSMB1.
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Sorry to hear this Emily. Sadly, despite huge efforts by many to change things, such views are ingrained in many academics. We can only hope it will change sooner rather than later.
Reviewer/panel comments to another rejected grant. Main theme was ”applicant has co-authored ~79 academic articles, >9,380 citations, h-index of 41. Only weaknesses is no stellar papers in top-tier journals”. How is this still legit?! #ImpactFactor #sfDORA #tired.
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RT @KieronSouth: Given my research interests this is super interesting. Doesn't make it any less terrifying though. Large-Vessel Stroke as….
nejm.org
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period. The authors report the patients’ clini...
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RT @DrAlexGranata: Very well done to my student Mary for winning the best poster prize at the #cambridgeneurosciences departmental AWAYDAY!….
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Fantastic! Great to see our programme research findings presented 😊 stay tuned for more data on Col4a1 contribution to #SVD @CamStroke @TomVanAgtmael.
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RT @CamStroke: Our article just out. How common are single gene mutations as a cause for lacunar stroke? Answered using sequencing panel. F….
neurology.org
ObjectivesTo determine the frequency of rare and pertinent disease-causing variants in small vessel disease (SVD)-associated genes (such as NOTCH3, HTRA1, COL4A1, COL4A2, FOXC1, TREX1, and GLA) in...
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Fantastic meeting yesterday with all of our consortium collaborators. Lots of exiting data from @Horsburgh_Lab @CamStroke @CaderLab @DrAlexGranata lab 🧪 🔬 and more! And now let’s get those papers out! It’s going to be a very prolific 2020! Stay tuned! #stroke #vasculardementia.
Another great meeting of @VaD_Matrix fighting vascular dementia @TheStrokeAssoc @Cambridgecardio @alzheimerssoc @TheBHF
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RT @CamStroke: Another great meeting of @VaD_Matrix fighting vascular dementia @TheStrokeAssoc @Cambridgecardio @alzheimerssoc @Th….
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RT @teamWorkstroke: We are so excited to be involved in the LOC planning for this meeting 🙌🏴🧠 along with @JosieNeuro @stu_art_here @H….
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RT @CamStroke: Interesting study suggesting #AD and vascular pathology’s have differing effects on #brainnetworks - but what influence does….
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Some of the amazing work from our programme on #CollagenIV #dementia and #stroke using #iPSCs Well done Mary!👏🏻.
Perfect poster picture of my student Mary presenting her work on iPSC-BBB model of collagen IV SVD at the 22nd International Symposium on Signal Transduction at the Blood-Brain Barrier in Wurzburg @CamStroke @VaD_Matrix
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RT @DrAlexGranata: Perfect poster picture of my student Mary presenting her work on iPSC-BBB model of collagen IV SVD at the 22nd Internati….
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RT @DrAlexGranata: If you are interested in stem cell disease modelling, mechanisms of atherosclerosis & inflammation in stroke and epigene….
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RT @CamStroke: Stroke is a syndrome not a single disease and determining the cause is important in guiding treatment. A practical guide to….
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Check out the latest review on #basement membranes and #collagen co-authored by two of our programme researchers @TomVanAgtmael and @Gaia_Brezzo.
Excellent job by @AnnaGatseva @Gaia_Brezzo and Yuan Yan (Angie) Sin (but I am biased!). Review article: Basement membrane collagens and disease mechanisms #Essaysinbiochemistry @PPPublishing. @UofGICAMS
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RT @DrAlexGranata: We are seeking an enthusiastic and experienced postdoc to work with us on very cool project, looking at the mechanisms o….
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Will be interesting to see if #NOTCH3 is also implicated in other Col4a1 mutations @Horsburgh_Lab @TomVanAgtmael.
Exciting data showing importance of SMC loss in ICH in COL4A1 and that this is modulated by NOTCH 3 pathway - might explain why ICH less common in CADASIL despite SMC loss @VaD_Matrix @StrokeGenetics @Cambridgecardio @Cadasilsupport1
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Amazing to see such great science at #ARUKconf! Stop by poster 11.2 & chat to @Gaia_Brezzo about novel mouse model of #SVD. If you are drawn in, we are recruiting in Manchester & Cambridge! If you have experience in #iPSCs we want to hear from you! @stu_art_here @DrAlexGranata.
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