Urszula Skupio
@USkupio
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Postdoc in Neural Circuits Lab @circuits_lab at Columbia University. Interested in stress, memory, social behaviors and reward system. @MarsicanoLab alumna.
New York, NY
Joined September 2019
'Untangling the multifaceted VTA responses to stress' by Urszula Skupio @USkupio, Alexander Harris @dr_alexharris & Abigail Polter @ampolter
https://t.co/WfgHO2VfUe
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Stress is complicated, right? @USkupio @ampolter & I had a hard think about the way acute & chronic stress impacts the different neural populations in the VTA & I’m really pleased with what we came up with. Just published in TINS. Check it out! https://t.co/HpJbQzmi8f
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This is a great story about what astrocytes and cannabinoids have to do with social transmission of stress in mice, be sure to check it out! Big congratulations Paula and all co-authors!
My PhD is out in @NatureComms! We showed that social transmission of stress in male mice impairs memory retrieval through a mitoCB1 mechanism in olfactory bulb astrocytes. Special thanks to @MarsicanoLab and @stressynomics, and to all the people involved! https://t.co/W01CgmoypI
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NCL lab retreat 2024! This year with an amazing view, great discussions and delicious lunch prepared by Alex!
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I am eally thrilled to share my first postdoctoral paper out in @NatureComms. Incredible collaborative effort! Many thanks to all the people involved and especially to @MarsicanoLab and Lisa Roux (first paper of the lab 🥳). https://t.co/SEV7nnGVqx
nature.com
Nature Communications - Whether and how cannabinoid type-1 receptors impact sensory functions in vivo is largely unknown. Here, authors show that their endogenous activity controls network dynamics...
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We are pleased to congratulate @GeoffreyTerral of @EinsteinMed on joining the 2023 cohort of #leonlevyscholars selected for the Leon Levy Scholarships in #Neuroscience, in partnership with the Leon Levy Foundation. 👏 Read more: https://t.co/JR2ITTTs0f
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NCL lab retreat 😎 We trained to give brief talks about our projects, discussed science, ate delicious BBQ and hiked!
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Instead, our data indicates that corticosterone-induced impairment of object recognition relies on CB1-dependent regulation of mitochondrial calcium dynamics. This suggests that exogenous and endogenous cannabinoids might act through different mechanisms in the brain! 4/4
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We assumed that the molecular mechanism of this impairment relies on CB1-dependent regulation of mitochondrial respiration, as seen with exogenous cannabinoid injection (as shown in Hebert-Chatelain et al, Nature, 2016), however, to our surprise...🥁 it doesn't! 3/4
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First, we found that injection of corticosterone impairs novel object recognition during consolidation and retrieval in mice through mitochondria-associated CB1 receptors in 2 different cellular populations: LC noradrenergic and hippocampal GABAergic cells, respectively. 2/4
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I am so excited to share with you our latest story with @MarsicanoLab published in @NeuroCellPress! For those interested, full free access text here: https://t.co/6u232sh3qf check🧵for a short summary! 1/4
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Today we had a lab picnic and said goodbye to Alan who is starting his lab soon! Congratulations and good luck @APNeuro!!!
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And another review out from our team! This time about endocannabinoid signaling in astrocytes, coordinated by @ErasoAbel together with @Pouvreau_S, Alex Pinto, @Neurocuriously and @USkupio! Give it a read if you like! https://t.co/lO5ufbI8kv
onlinelibrary.wiley.com
Astrocytes have a functional and diverse endocannabinoid system. Cannabinoids are able to interact with astrocytes to modulate their functions and their communication with neurons.
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We are attending #FENS2022! @FENSorg These is a summary of the posters our lab members are presenting, looking forward to discuss in person with all of you interested in endocannabinoids! @Imane_Hurel @Neurocuriously
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Hello science twitter! 🧠😃 We are excited to launch our new lab account where we will share exciting science in the field of stress and reward systems as well as updates from our daily lab life!
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This year during symposium of @NCMagendie we presented new exciting data about the role of CB1 in different effects of stress!
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After 3,5 years I am saying goodbye to the @MarsicanoLab. It has been a truly amazing time and I want to say a big THANK YOU to all the incredible people that made this postdoc so special!
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