Tybulewicz Lab
@TybulewiczLab
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Based @TheCrick, we research in two main areas: Signal transduction in the immune system and the Genetics of Down syndrome
Francis Crick Institute
Joined April 2021
Congratulations to Joshua Biggs O'May and other members of the team for a great paper showing that water influx is needed for T cell activation and division. An unexpected role for water. Likely to be true in many other cell types too.
nature.com
Nature Communications - T cell antigen receptor stimulation by the ligand antigen triggers multiple downstream pathways that affect CD4 + T cell function. Here authors show that...
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A look back on a 2024 highlight in the Tybulewicz lab! Damaris successfully completed her viva in November has been enjoying her first months as Dr Damaris Bennett in the lab 🎉🥳
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Congratulations to Rif and Eva on winning a Science Achievement award at the annual Crick Awards in recognition of all their hard work and a fantastic paper! 🥳
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Well done to Rif for an excellent presentation at the Crick Annual Science Meeting. Rif presented her work on causative genes of CHD in Down Syndrome, a project shared with Eva Lana-Elola which is now published in Science Translational Medicine! DOI: 10.1126/scitranslmed.add6883
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Exciting @EMBO meeting on Chromosome Segregation and Aneuploidy on the beautiful shores of @LagoMaggiore .
meetings.embo.org
Aneuploidy is a hallmark of cancer and developmental disorders such as Down syndrome. Understanding how cells accomplish faithful chromosome segregation and how chromosomal instability (CIN) impacts …
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We have a vacancy for a Postdoctoral Researcher to join our lab @TheCrick to study congenital heart defects in Down syndrome. To follow on from work we published in Science Translational Medicine.
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Exciting opportunity for a PhD student to work jointly with @RachelSEdgar and our lab @TheCrick to study the role of water potential and bio-condensates in T cell biology.
crick.ac.uk
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RT @LonDownS: Happy World Down Syndrome Day 2024 🎉 Thank you to everyone who joined us for a fun-filled day of talks and activities at The….
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Happy #WorldDownSyndromeDay2024 from everyone in the Tybulewicz lab! Once again we are celebrating in our odd socks!🧦 #lotsofsocks
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RT @TheCrick: For #WorldDownSyndromeDay2024 Crick researcher Rifdat Aoidi from @TybulewiczLab spoke to actor @Sarah_gordy. Sarah spoke abo….
crick.ac.uk
Today marks World Down Syndrome Day, an international awareness day aiming to raise awareness about Down syndrome and promote the rights, inclusion, and well-being of people with Down syndrome. The...
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RT @EmilyBlackburn9: On Saturday we held our annual World Down Syndrome Day event at The Francis Crick Institute. We heard from brilliant s….
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RT @LonDownS: We are looking forward to seeing everyone at WDSD on Saturday March 16th! . A reminder that you must have a ticket in order t….
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RT @TheCrick: Researchers from the Crick’s @TybulewiczLab and @UCL have identified a gene that causes heart defects in Down syndrome. By….
crick.ac.uk
Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21. Reducing the...
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RT @EmilyBlackburn9: Super excited for our next WDSD celebration on March 16th 2024! The event is open to anyone with Down Syndrome and the….
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Congratulations to @Leonard_deBoer for a beautiful study that has finally been published in @NatureComms. T cell migration requires ion and water flux into the leading edge. See Leon's thread for more details.
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Happy #WorldDownSyndromeDay from the @TybulewiczLab! .We are sporting our odd socks to mark the occasion 🧦 #WDSD2023
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