TurleyLab
@TurleyLabGNE
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Studying stromal cell function in inflammation, fibrosis and cancer! Tweets by Shannon Turley and Turley Lab Members
South San Francisco, CA
Joined March 2019
Interested in restoring vision for people with AMD and other diseases of the retina? If so, then please check out this exciting new opportunity in ophthalmology research and drug development at Genentech! Join our stellar community.
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RT @akshayk25: Super fun celebrating a successful 2022 with @TurleyLabGNE and @SorenMuller1 and our teams! Looking forward to a restful bre….
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Adore this community beyond words! 💜 Happy Holidays everyone. Here’s to a year ahead teeming with curiosity, discovery and collaboration.
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Terrific job opportunity with a stellar group leader focused on solving cutting-edge, B cell-related questions in human disease and drug development. The Yewdell Lab is a new addition to Immunology and Regenerative Medicine at Genentech. Join our community!.
Pls RT: The Yewdell Lab is hiring 2 peeps! Unparalleled resources and collaboration, amazing benefits, beautiful campus, healthy work-life balance. AND DID I MENTION B CELLS!!!
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RT @SciImmunology: Targeting pathogenic CD4 #Tcells with CAR T cell therapy reverses the progression of multiple sclerosis-like disease in….
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RT @genentech: Fibroblasts are key structural cells & some types are associated with cancer progression. In @Nature, @akshayk25, @SorenMull….
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Feeling incredibly humbled and proud of this work with so many stellar trainees and long-standing collaborators! Giving special shout outs to co-corresponding author @SorenMuller1 and lead author @akshayk25. Here’s to teamwork and passion projects!
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RT @akshayk25: Using novel genetic tools, we show TGFβR2 signaling in healthy Dermatopontin (DPT)+ universal fibroblasts is essential for L….
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RT @akshayk25: Previous scRNAseq studies in cancer identified a predominant population of activated LRRC15+ myofibroblasts, that express hi….
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RT @akshayk25: Once LRRC15+ CAFs form, how do they impact tumor immunity? We made an LRRC15-DTR mouse to selectively ablate LRRC15+ CAFs fr….
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RT @akshayk25: Kinetic scRNAseq of LRRC15+ CAF depleted tumors showed a recalibration of the tumor fibroblast compartment back towards a un….
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RT @akshayk25: Immunologically, depletion of CD8+ T cells in LRRC15+ CAF depleted tumors reversed the improved tumor control. Additional an….
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RT @akshayk25: Ultimately, this enabled us to ask if LRRC15+ CAFs limit response to immunotherapy. Here we find depletion of LRRC15+ CAFs m….
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RT @akshayk25: Imaging of tumors showing CD8s in close proximity to LRRC15+ CAFs further suggested cross-talk between these cells. And when….
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RT @akshayk25: Most importantly, these exciting findings (and many more in the paper) were only possible b/c of the contributions of our in….
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RT @akshayk25: Together, our findings tie together computational inferences, clinical associations, and now, in vivo validation, to support….
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RT @akshayk25: Along with @TurleyLabGNE, @SorenMuller1, and our team @genentech, I'm thrilled to share our newest work out now in @Nature:….
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Delighted to share a terrific new study from a group of stellar fibrosis scientists at @Genentech. Congrats @NingDingGNE and team! .
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RT @TYewdell: The Yewdell lab @genentech is born!! If you are a cellular immunologist interested in B cell biology, immunological disease,….
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RT @JudithAgudo1: the first paper of the lab has been published. I feel the luckiest in the universe🤩 we found a sub-population of tumor ce….
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