Tobias Hermle
@TobiasHermle
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Research group leader and attending physician Department of Nephrology, Medical Center - University of Freiburg
Freiburg, Germany
Joined January 2023
The Drosophila slit diaphragm looks like a fishnet. It appears that the molecular architecture of the kidney slit diaphragm is evolutionarily conserved from Drosophila to mice!
biorxiv.org
The kidney filters large volumes of blood plasma, relying on the glomerulus for the filtration. The slit diaphragm, a critical component of the glomerulus, is formed between podocytes by the immuno...
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Now open access in @NDTsocial Extrarenal manifestations in inherited kidney diseases 🧐The interplay between genetic variants and molecular pathways underscores the importance of exploring the extrarenal aspects of inherited kidney diseases. ▶️ https://t.co/Z7uMc44erH
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Using the glomerular basement membrane model in Drosophila nephrocytes, this study reveals that matrix receptor-mediated cues ensure correct positioning of the slit diaphragm and the overall filtration barrier architecture https://t.co/IApn4u9VkE
@MartinHelmstdt1
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Had a great time at #pod23 🐙. Thank you so much to the organizers, especially the hosts @KSusztak and Larry Holzman. Looking forward to Hamburg! @Tobias_B_Huber
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The registration for our International @SFB1453_NephGen Symposium is now open! Join us for 4 days of exciting kidney science, brilliant speakers and a fun social program here in the Black Forest! https://t.co/W6GZ7QODmY
#NephGenSymposium #NephGenSymposium2023 #NephTwitter
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Still think it's fun to watch slit diaphragms of #nephrocyte disintegrate after acute Rab5 silencing
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Variants in TBC1D8B cause isolated nephrotic syndrome. This study found variants in TBC1D8B are not infrequent among patients with FSGS. TBC1D8B, functioning in endosomal maturation and degradation, is essential for nephrin trafficking https://t.co/ppdJIAeWJZ
@MartinHelmstdt1
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