Gut Onc Lab
@TheGutOncLab
Followers
249
Following
249
Media
17
Statuses
184
A collaborative space led by GI medical oncologists to share research, learn together, and highlight what's evolving in GI cancers | #GIonc #OncTwitter
Joined June 2025
A great lineup of excellent speakers at the Onc Brothers @OncBrothers event at #GI26 including our very own @TimothyJBrownMD
Just getting a hang of the data from #ASH25 and #SABCS25 — But #GI26 is upon us! Let’s 🗣️ how #GI26 will change our practice/SoC! ⭐️InPerson: Jan 9, 2026 ⭐️Time: 6:30-8:30PM - Panc-Biliary - Upper GI - CRC & NET ⭐️Register https://t.co/d7kIBwJq3s
#OncTwitter @OncoAlert
0
1
4
At Cure CRC today. ~100 of the leading colorectal cancer researchers, clinicians, advocates, and industry partners in one room, all aligned around a single goal: curing colon cancer (and me… I guess I snuck in). It’s inspiring—and also a reminder that we’re not there yet. We’re
2
11
35
ALASCCA showed that a century-old drug could change adjuvant outcomes in colorectal cancer. This work helps explain the biology behind that signal. New mechanistic data in NEJM identify platelet-derived thromboxane A2 as an active suppressor of antitumor immunity during
nejm.org
A new study shows that aspirin enhances antimetastatic immunity by decreasing platelet activation, thereby releasing T cells from suppression by thromboxane A2.
1
12
35
I had the chance to speak at the Northwell Health Pancreas Symposium on Emerging Therapies in PDAC. Big picture: we are not going to chemotherapy our way out of pancreatic cancer. The next gains come from biology-driven, precision strategies. A short thread 🧵👇 @OncoAlert
2
7
33
This is the first paper out from @TheGutOncLab @Deebacca @GIMedOnc @UGrewalMD that evaluated FOLFIRI-Ram compared to Ramucirumab-Paclitaxel in the @flatironhealth database
1
3
13
Great watching @UGrewalMD highlighting advances in NET care and the work being to address inequities in NET care. Also he’s now board certified!! Watch 👇🏽 @TimothyJBrownMD @TheGutOncLab
https://t.co/VbssWlpDdM
https://t.co/MMDjiJcl2D
1
3
12
Interview I did with @OncNewsCentral regarding treatment selection for 1L gastric cancer https://t.co/DqWzdbsldG
@UGrewalMD @GIMedOnc @TheGutOncLab
oncologynewscentral.com
Options are expanding for patients with advanced gastric cancer, but a lack of head-to-head trial data between treatments makes decision making challenging.
0
2
8
About 2 years ago- I got a cold message from a guy who was looking for research mentorship. I reluctantly (as a fellow myself) said yes. 2 years and many manuscripts, poster presentations and concepts still in the pipeline later- I get to continue to mentor @SuriyaBaskarMD at
2
4
68
Match day! Looking forward to finding out who will be joining us @utswcancer @UTSWHemeOnc next year! @littlejonesmd @MonikaKumarMD @TheGutOncLab
0
2
9
I had the great fortune of sitting down with @PoHienEar from @UIowaCancer to discuss her ongoing work focused on GLP1 Receptor Agonists in Neuroendocrine Tumors. She was very kind to let me share the interview on my substack. Link: https://t.co/sKIgC4l14g Link to her recent
0
7
17
Thank you @CureNETs for the opportunity to discuss some key scientific updates from @NANETS1 2025 Annual Symposium. 🦓🎗️ Link- https://t.co/xxPyDBrhh4
0
3
18
Watch @GIMedOnc @TimothyJBrownMD and @UGrewalMD unpack some data from #ESMO25 for @VuMedi @VuMediHemOnc
#ESMO2025 @GIMedOnc @UGrewalMD @TimothyJBrownMD unpack the latest in GI oncology—from MATTERHORN’s OS data and NICHE-2’s neoadjuvant impact to the ASPEN trial’s real-world implications for organ preservation in NETs @TheGutOncLab Full recap on #Vumedi:
0
3
5
Landmark paper from @MSKCancerCenter led by my friend @rohit_thum on landscape of DLL3 in GEP Neuroendocrine neoplasms. DLL3 is not prognostic, enriched in small cell histology and can be found in 40% of well diff G3 NENs! Functional imaging offers a promising platform for DLL3
1
7
24
Very excited to see this in print. Our latest commentary highlighting the "missing piece of the puzzle" in neuroendocrine neoplasm classification, published in Med @CellPressNews . NENs are classified based on morphology, site of origin, and Ki-67 proliferation indices. These
4
19
55
Teamed up with #BrysonKatona & #LindaLee to make sense of the ever-confusing world of #NETs in our @AGA_Gastro review—hope it helps every GI and Onc specialist who meets these sneaky tumors on a “routine” scope https://t.co/i5KN51TEyy
@FoxChaseCancer @PennMedicine @BrighamWomens
gastrojournal.org
Neuroendocrine tumors (NETs) represent a heterogeneous group of neoplasms with diverse biological and clinical behavior, and gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are the most...
2
19
57
Last week's episode of Oncology on the Go featured a discussion between @GIMedOnc, @UGrewalMD, and @TimothyJBrownMD about the top GI abstracts from #ESMO25! Listen here: https://t.co/4HtG3BaxLP
#crcsm #NETs | @TheGutOncLab
0
3
4
Tune in to @colontown DocTalks to listen to Dr Hornstein discuss key colorectal cancer updates from ESMO 2025. 👇
Excited to share Colorectal Cancer updates from ESMO 2025 with Colontown this Tuesday November 11th at 11:30AM! We'll talk about the practice-changers, the puzzles and the take-aways that can impact patient-care today. Link below: https://t.co/ITy3gHvc0P
#CRCSM @OncoAlert
0
0
2
If you’re within five years of training—or still in it—and work in neuroendocrine neoplasms (NETs/NECs), we want to hear from you!! Please fill out this survey which will help us understand early career perspectives in the field and identify areas of unmet need. Link-
2
6
23
4 GI Malignancy studies that we touched on with @rachnatshroff for #ESMO25: ✅ #DYNAMICIII ✅ #STELLAR303 ✅ #MATTERHORN ✅ #FORTITUDE101
#OncTwitter #MedTwitter @OncUpdates @myESMO @OncoAlert #gism
GI Malignancies Highlights from #ESMO25 with @rachnatshroff! ✅ #DYNAMICIII & #PEGASUS ✅ #STELLAR303 ✅ #MATTERHORN ✅ #FORTITUDE101 Full Discussion: - https://t.co/7tZQJM2KWc - Also on “Oncology Brothers” podcast #OncTwitter #gism @myESMO @OncUpdates
0
42
97
Big day for a rare disease 🎉🧬 The new NCCN Guidelines for Appendiceal Cancer just dropped — and they’re fantastic. For the first time, this rare and often misunderstood disease finally gets its own dedicated guidance, instead of the old “just follow colorectal cancer”
3
32
122