Sudhin Thayyil
@SudhinThayyil
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Professor of Perinatal Neuroscience at Imperial College London
Cambridge, England
Joined March 2018
38% of babies with mild HIE have special educational needs at School age. Can cooling prevent this? World’s first RCT of Cooling in Mild HIE (COMET) opens recruitment – 426 babies from 50 NHS hospitals. https://t.co/CAUglm9v4w
@PeepsHie @Atul_Monash @BAPM_Official @ImperialPaeCH
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Best COMET site initiation ever! Huge thanks to Mel and the team at Plymouth – even the foundation officers got trained on expanded modified Sarnat staging. Excited to open COMET at Derriford Hospital soon! @NewbornBrains @PeepsHie @HopeforHIE @ImperialPaeCH @Atul_Monash
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Congratulations to Dr. Vaisakh Krishnan on successfully defending his PhD Viva! 🎉 His in-depth research on the timing and origin of brain injury in HIE in LMIC is truly outstanding. @ImperialBrains @PeepsHie @HopeforHIE @ImperialPaeCH
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Fantastic opportunity to learn & engage with health professionals in Hisar, Haryana, India this week running @onesimeducation workshops to improve obstetric & newborn emergency management. #IPE #SimEd #MedEd Courtesy Dr Reema Garegrat @SudhinThayyil @CPN_NeoNeuro @ImperialPaeCH
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Congratulations to Dr Pallavi Muraleedharan on successful PhD defence on systemic factors and a prediction tool for HIE using AI @PeepsHie @HopeforHIE @Atul_Monash @ImperialBrains @ImperialPaeCH @OBSevidence @DameTina1
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Is Quantitative research from Mars and Qualitative from Venus? We need to both to make sense of the data and to improve health outcomes – and that is all what matters ! @ImperialMed @ImperialBrains @ImperialPaeCH @PeepsHie @HopeforHIE @NeonatalSociety @OBSevidence @DameTina1
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One more Super PhD without any corrections – Congrats to Dr Stuti Pant PhD. @ImperialBrains @ImperialPaeCH @PeepsHie @HopeforHIE @Atul_Monash @OBSevidence @Blisscharity
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National Neonatology Forum (India) should be commended for their thoughtful position statement for de-implementation of cooling in LMIC – "primum non nocere" https://t.co/iIGGGKjZ5p
@Nnfindia1 @PeepsHie @HopeforHIE @ImperialPaeCH @Atul_Monash @Dr_KS_Gautham @NewbornBrains
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Congrats to Constance Burgod on an outstanding PhD on gene expression in HIE. Finally, there is scope for HIE disease stratification. Start of an illustrious academic career (No head-hunters please)@ImperialPaeCH @PeepsHie @HopeforHIE @ImperialBrains @ImperialInfect
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Erythropoietin monotherapy given within 6h for 9 days, halved neonatal death in this multicentre pilot RCT from South Asia. Timing looks key to neuroprotection in HIE? https://t.co/3xm4OUt8AM
@Atul_Monash @PeepsHie @HopeforHIE @ImperialPaeCH @ela_chak @OBSevidence
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COMET pilot trial out (JAMA N) – highest [NAA] level in normothermia, followed by 48 h and lowest with 72 h cooling. Suggest caution on cooling babies with mild HIE outside a clinical trial @Atul_Monash @ImperialBrains @ImperialPaeCH @HopeforHIE @PeepsHie
https://t.co/0obe64h4G5
jamanetwork.com
This pilot randomized clinical trial examines the effect of 48 and 72 hours of whole-body hypothermia compared with normothermia on cerebral magnetic resonance biomarkers among neonates with mild...
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Super proud of my "Early Neurodevelopment Clinic" team. We were early adopters of international guidelines: https://t.co/o6i0t1h6f1 Read about sensitivity & accuracy of early assessments in new 📃 by @DrAbdulRazak_MD in @JAMANetworkOpen: https://t.co/PR1Hk57n7j
@EBNEO @ESPR_ESN
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Levetiracetam not controlling electrographic seizures but are we giving it too late? https://t.co/ysOcNsNIlM
@ImperialPaeCH @Atul_Monash @NeonatalUpdate @EBNEO @youngepilepsy @IlaeWeb @ILAEBRITISH @CPN_NeoNeuro
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Gene expression shed lights into the high occurrence of HIE in South Asia and lack of hypothermic neuroprotection. https://t.co/azf8jcNtwG
https://t.co/yFZY5jbDoR
@Atul_Monash @ImperialPaeCH @NIHRglobal @OBSevidence @NeonatalUpdate @EBNEO @acunningID @MARCH_LSHTM @Azeem_Majeed
imperial.ac.uk
Researchers from Imperial College London have shown that a blood test can pinpoint the underlying cause of brain injury in newborns.
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One of the best global health research teams doing world class qualitative research - Great opportunity
Exciting opportunity for a midwife to join our team - Senior Lecturer in Midwifery and Global Health. https://t.co/kjBOWaRzdz
@Yanarichens @traceymills18 @ActisValentina @Sabina71383023 @LizAyebare
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New IPD meta-analysis investigating the impact of cord strategies on preterm mortality published in @TheLancet by @LeneSeidler
#neotwitter #EBNEOAlerts
https://t.co/fokONG5DF4
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“Seven lessons to Share” Prof Lucy Chappell (Chief Scientific Advisor, Dept of health, UK): Do watch this, especially, if you are an early career researcher-It could change your life @gatesfoundation @ImperialPaeCH @Atul_Monash @Azeem_Majeed @NIHRglobal
https://t.co/NMm45ukvXr
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CRADLE VSA cited in this Economist article as an innovation that has contributed to this remarkable reduction in maternal mortality in Sierra Leone. @NIHRglobal @welbodi https://t.co/87JYmb36oI
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(1) Cooling ineffective in LMIC, irrespective of birth depression severity/acidosis (2) 35% adverse outcomes even after short birth depression – WHY? https://t.co/FvqbmtyQEJ
@ImperialPaeCH @OBSevidence @LucyChappell2 @NIHRglobal @Atul_Monash @gatesfoundation
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This week @LucyChappell2 visited Bangalore Medical College to meet research teams working on two pioneering NIHR Global Health Research projects in maternal and newborn health. Read more: https://t.co/wAR34byX4j
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