SternLab @sternadi.bsky.social
@SternLab
Followers
3K
Following
2K
Media
24
Statuses
891
Studying the evolution of viruses, microbes, their hosts and beyond at Tel-Aviv University.
Israel
Joined June 2017
Millions of SARS-CoV-2 seqs out there. what info do they hide? Combining phylogeny & deep learning we infer hundreds of chronic infections & show they predict future evolution. Want to know how? 🧵. @SheriHarari @Daniellemlrs @shay_fleishon @BursteinLab.
4
32
129
5. Finally we speculate that cheaters are probably very common and may even serve as stepping stones on the way to generate novel forms of viruses. Stay tuned!.
0
0
3
4. This is like pulling the strings of a marionette - cheaters change one part of the replication cycle and helpers compensate, all with the "aim" of producing more cheater progeny.
1
0
2
3. When cheaters are evolved, helper mutations are added onto the genome. If a cheat is defective in replication, we find that helpers alter lysis and entry. And when a cheat is defective in lysis, we find helpers alter replication.
1
0
2
2. We find that cheater viruses of the MS2 bacteriophage occur in a really small region of the genome, where there are three overlapping genetic functions. This is normally a conserved region but cheats. overcome the challenge.
1
0
2
1. Cheaters are both defective viruses, but outcompete the WT virus when both viruses co-infect a cell. Who would have thought viruses could be so sly?.
1
0
2
RT @ruthlessrousso: ״המחיר שנשלם על החזרת החטופים יהיה יקר, אבל המחיר שנשלם על אי החזרתם יהיה יקר בהרבה. כי לעולם לא נתאושש כעם. לא נוכל ל….
0
137
0
כמה כואב הבוקר הזה. והכינוי מפקירים ממש לא מספיק חזק כדי לתאר את חבורת החלאות שיושבת בשלטון כרגע.
0
1
18
Heartbroken to share that Yagev Buchshtab, brother of PhD student Nufar, was murdered in Hamas captivity. Too much unbearable pain. This should not have ended, or started, this way.
20
32
300
RT @Thedayafter24: הסטודנטים והסטודנטיות מפסיקים לשתוק. עסקת חטופים עכשיו!. מחר, 8.5, בשעה 12:00, נקיים הפגנה באוניברסיטאות בדרישה ברורה: ע….
0
6
0
RT @SpencerGuard: IMO Israel has implemented more measure to prevent civilian casualties in urban warfare than any other military in the hi….
0
3K
0
RT @AsherLeeks: Announcing the Social Lives of Viruses 2024!. Do you study social evolution in viruses? Do you want to?. Join us in Puerto….
0
33
0
Our paper is now out @SheriHarari @Daniellemlrs @shay_fleishon @BursteinLab .I want to be happy but my heart is still torn to pieces with hostages incl. kids,women,elderly, being held for 107 days.
Millions of SARS-CoV-2 seqs out there. what info do they hide? Combining phylogeny & deep learning we infer hundreds of chronic infections & show they predict future evolution. Want to know how? 🧵. @SheriHarari @Daniellemlrs @shay_fleishon @BursteinLab.
7
4
57
RT @AvivaKlompas: This is Itai Svirsky. He was taken hostage to Gaza on October 7. Hamas forced him to participate in a propaganda video an….
0
3K
0
RT @BillAckman: In light of today’s news, I thought I would try to take a step back and provide perspective on what this is really all abou….
0
19K
0
RT @IldemocracyHQ: 🎶 Homeland Concert 🎤. A powerful plea from 1000 Israeli musicians. We must bring every hostage home. NOW! 🇮🇱. ✨ Listen a….
0
455
0