Small GTPases
@SmallGTPases
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Small GTPases features research focused on these key signal transducing proteins that are involved in every facet of biology.
Joined December 2015
VPS34 Governs Oocyte Developmental Competence by Regulating Mito/Autophagy: A Novel Insight into the Significance of RAB7 Activity and Its Subcellular Location - Liu - 2024 - Advanced Science - Wiley Online Library
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USP7 deubiquitinates KRAS and promotes non-small cell lung cancer
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KRas4b–Calmodulin Interaction with Membrane Surfaces: Role of Headgroup, Acyl Chain, and Electrostatics | Biochemistry
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RhoA regulates oligodendrocyte differentiation and myelination by orchestrating cortical and membrane tension. Glia | Neurobiology Journal | Wiley Online Library
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ASAP1 and ARF1 regulate myogenic differentiation in rhabdomyosarcoma by modulating TAZ activity
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YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer
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Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes | The EMBO Journal
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Endosomal Trafficking Bypassed by the RAB5B‐CD109 Interplay Promotes Axonogenesis in KRAS‐Mutant Pancreatic Cancer - Zhang - Advanced Science - Wiley Online Library
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Overexpression of CDC42 causes accumulation of DNA damage leading to failure of oogenesis in triploid Pacific oyster Crassostrea gigas.
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Motorless transport of microtubules along tubulin, RanGTP, and salt gradients
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CDC42 deficiency leads to endometrial stromal cell senescence in recurrent implantation failure
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Spatial multiplex analysis of lung cancer reveals that regulatory T cells attenuate KRAS-G12C inhibitor–induced immune responses | Science Advances
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Oncogenic KRAS Mutations Confer a Unique Mechanotransduction Response to Peristalsis in Colorectal Cancer Cells
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In @eLife: Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover
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A noncanonical GTPase signaling mechanism controls exit from mitosis in budding yeast | PNAS
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Pharmacologic restoration of GTP hydrolysis by mutant RAS
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#PLOSONE: Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development.
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MiR‐144/451 attenuates lipopolysaccharide‐induced lung inflammation by downregulating Rac1 and STAT‐3 in macrophages - He - 2024 - Journal of Biochemical and Molecular Toxicology - Wiley Online Library
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