1.) Interesting article on the possible cause of post-exercises malaise in ME/CFS https://t.co/ECNYyqBXyk
@dg_mecfs @MECFS_Freiburg @MECFS_Bayern Interstingly, many Post-Finasteride Syndrome patients also report Post-exercises malaise...
4
5
18
Replies
2.) The article states that in ME/CFS - inflammatory markers like (hs-) CRP increase - IL-10 is increased - glucose and citrate don't respond with elevation to exercise - bacteria enter the blood stream after exercise which probably causes brain fog, fatigue and malaise etc ...
1
0
5
3.) Interstingly, a recent study by @CosimoMelcangi found inflammation in the gut of rats after 1 month after withdrawal of finasteride (increase of IL-1β and TNF-α). Leaky gut has not been confirmed in these animals - although I personally find it likely happens in PFS.
3
0
7
4.) I find it likely that brain fog in PFS is a sign of neuroinflammation. Gut inflammation and leaky gut after finasteride withdrawal might cause bacteria and LPS to enter the blood stream and cause neuroinflammation, depression & fatigue...
3
0
5
5.) Note that some PFS patients report to have a window of improvement after use of antibiotics or inuspheresis before usually relapsing. The bacteria could theoretically also cause autoimmune antibodies when getting in contact with the immune cells in the blood.
4
1
9