Shuvro Roy, MD
@ShuvroRoy
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Assistant Professor @UWNeurology. Former @hopkinsneurons @UCLANeurology. Mostly memes, politics, and basketball, sometimes the brain
Los Angeles, CA
Joined April 2009
This announcement is long overdue, but #somenews: I’m thrilled to be joining @UWNeurology as an Assistant Professor in the fall!. Grateful beyond belief for the last 2 years at @hopkinsneurons. I've grown across the board as a clinician, educator, and researcher thanks to you all
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RT @TheSumairaFDN: We're coming to Seattle!. We're inviting patients & caregivers impacted by #AE, #CNSvasculitis, #MOGAD, #neurosarcoidosi….
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RT @TheSumairaFDN: When rare disease besties link up: Salt Lake City edition 🏔️ . Thank you once again @StaceyLClardy, @UofUNeurology, @ext….
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RT @MayoNeuroFellow: Congratulations to Dr. Syc-Mazurek (Neuro-ophthalmology fellow) on her publication “MRI characteristics during attack….
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RT @GreenJournal: Neurology Podcast: Dr. Shuvro Roy and Dr. Daniel Blockmans discuss the efficacy and safety of upadacitinib as a treatment….
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RT @TheSumairaFDN: SAVE THE DATE | TSF is coming to Seattle on October 18th!. In collaboration with Dr. @ShuvroRoy at @UW, we're hosting a….
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RT @olsonplanner: Congrats, you’re a brand-new attending. You just finished residency, and now someone hands you a contract that says:. “$….
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8/.📄 Read the full paper:.🧠 Core Diagnostic Features of Stiff Person Syndrome: Insights from a Case-Control Study.🔗 🙏 Thanks to the amazing patients and team who made this work possible. #NeuroTwitter #Neuroimmunology #StiffPersonSyndrome
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7/.📢 Let’s get better at recognizing SPSD. Why it matters:.⏱️ Early Dx → early immunotherapy → better outcomes.📊 Stronger diagnostic criteria → better trials.🔁 Repeat testing off-IVIG = reduce false positives.
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6/.👩⚕️ Takeaways for neurologists:.✔️ Think SPSD when stiffness is axial & triggered.✔️ Order antibody titers (and know what high means!).✔️ Request EMG with co-contraction & CMUA.✔️ Evaluate brainstem/cerebellar signs in SPS-plus suspicions.
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5/.💡 So what actually helps with diagnosis?.Multivariate analysis showed:.-High-titer antibodies (OR >500!).-Classic EMG findings.-Posterior fossa signs (SPS-plus). Clinicians: Look for patterns, not just the paraclinical!.
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4/.🤯 Misdiagnosis was common.~74% of patients had another diagnosis before SPSD was recognized.Most common:.-Neuropathy.-Myelopathy.-Functional disorders.Misdiagnosis = delays in care by nearly 1 year on average ⏳.
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3/.🔍 Key findings for SPS-plus:.-Cerebellar 🌀 and brainstem 🧠 involvement.- Ocular signs, dysarthria, ataxia.- CSF GAD65 Ab = 💯 specific. GAD65 titers still mattered — even >1,000 IU/mL helped separate signal from noise 🎯.
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2/.🔍 Key findings for classic SPS:.Torso/lower limb involvement. Lumbar hyperlordosis. Triggered by noise, cold, open spaces. High-titer GAD65 antibodies (>1,000 IU/mL). EMG: Co-contraction + continuous motor unit activity 💪⚡.
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1/.SPS is rare, disabling, and frequently misdiagnosed. We reviewed over 200 cases seen at @HopkinsMedicine to identify which clinical + paraclinical features truly help distinguish:.✅ Classic SPS.✅ SPS-plus.❌ Not SPS at all.
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🧵NEW STUDY in @JNeuro.Stiff Person Syndrome is one of the most misdiagnosed neuroimmunologic disorders. How do you tease out what actually helps you get the diagnosis right?. We break it down in the largest case-control study to date on SPSD 🧠💥.👇.
link.springer.com
Journal of Neurology - Stiff person syndrome spectrum disorders (SPSD) are rare, disabling neuroimmunological conditions with no consensus diagnostic criteria, making diagnosis challenging....
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Love this advice! I always struggled trying to get through a textbook in residency and find contextual learning to be much higher yield and sustainable.
Instead of reading a textbook from front-to-back as a trainee, consider reading up on one case per day. Drop those cases in a categorical bucket as you build you framework of neurology. Then you can reach back for them when you encounter something similar. You’ll be surprised at.
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RT @MariaIReyesMan1: Pardo Lab and #NEAS presentation. Thank you @AANmember for the opportunity to talk about Neurodengue! .
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RT @UWNeurology: If you are interested, please put your application in to uwneuroscholarships@uw.edu. Deadline is April 1, 2025! https://t.….
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RT @60Minutes: “Twelve days ago, people knew where their next paycheck was coming from. They knew how they were going to pay for their kids….
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