1/ Six years in the making! Our preprint on SORDINO fMRI is out. We're sharing the raw data and sequence to facilitate brain-wide mapping in awake, behaving rodents. If this could be useful to your colleagues and friends, please help spread the word! .

This is really interesting work, @Chuang_Lab! Congrats!!!.

RT @uzemye: #ISMRM #ismrm2025

Very much looking forward to the opportunity to share more animal work at @OHBM. Thank you, @MeyerBaese, Lauren, and @ShellaKeilholz, for organizing this!.

On Thursday (May 15) afternoon at 15:33 in the preclinical brain imaging oral session, @LiMingHsu2 will present a chemogenetic fMRI study building on our prior work (, studying how PVT modulates locus coeruleus-induced MD-PrL connectivity and behavior.

On Wednesday (May 14) afternoon at 15:45 in the multimodal fMRI oral session, @LiMingHsu2 will cover a recently published story about the specificity of “optogenetic terminal stimulation”:

On Wednesday (May 14) afternoon at 13:30 in the preclinical fMRI e-poster session, Weiting Zhang will discuss our initial attempts to resolve what causes synchronous resting-state connectivity in the striatum between two hemispheres.

On Monday (May 12) afternoon at 17:12 in the fMRI acquisition/contrast oral session, Sheng Song (@Sheng_S7) will give an overview of SORDINO and its use in awake behaving mice.

On Monday (May 12) afternoon at 16:48 in the Neurofluid oral session, Sungho Lee (@shleevet) will present the use of SORDINO on mapping glymphatic dynamics and choroid plexus efflux.

Also on Monday (May 12) morning at 8:15 in the multimodal e-poster session, @LiMingHsu2 will showcase the use of miniscope calcium imaging during SORDINO fMRI and how it may help examine the clusters of cells in PrL linking to distinct large-scale networks.

On Monday (May 12) morning at 8:15 in the multimodal e-poster session, Tatiana Shnitko will discuss the use of fMRI, electrophysiology, and electrochemistry to study dopaminergic modulation of connectivity dynamics and stress-driven repetitive behaviors.

On Monday (May 12) morning at 8:15 in the fMRI acquisition e-poster session, Sam Booth will demonstrate the use of @uzemye’s and @sjsawiak’s PETALUTE for fMRI, featuring a golden angle scheme to achieve flexible spatiotemporal resolution with multi-echo capability!

Come meet @camri_unc members during @ISMRM!. On Saturday (May 10) at the @bruker event and Monday (May 12) at 14:01 in the fMRI power pitch session, @TzuHaoHarryChao will talk about his work mapping inter-brain functional connectivity in socially interacting mice using SORDINO.

RT @bruker: We are excited to highlight one of our finalists, in no particular order. This innovative study uses a custom-designed 3D-pri….

💡Optogenetic stimulation of projection terminals is often thought to preferentially modulate downstream targets. In our recent fMRI study led by @LiMingHsu2, we compared cell body and terminal stimulations, showing that potential antidromic effects shouldn’t be overlooked.👇.

13/ The sequence, data, and scripts from this work are available with the manuscript and via We thank fMRI pioneers and those advancing zero- & ultra-short TE sequences for their inspiring work, and we hope this manuscript helps other labs adopt SORDINO!.

12/ SORDINO for glymphatic dynamics💧: Using Gd contrast, SORDINO enables brain-wide tracking of CSF influx without susceptibility artifacts. Its silent acquisition paves the way for studying glymphatic function in awake and sleeping mice!

11/ SORDINO for cross-brain coupling during social behavior 🐭🐭: We developed a dual-mouse hyperscanning platform, enabling simultaneous fMRI of two interacting mice. SORDINO reveals synchronized inter-brain activity in DMN & SN, uncovering neural dynamics of social interactions

10/ SORDINO maps skilled motor actions in mice🤏: We designed a food pellet delivery system and trained mice to reach and grasp during fMRI. SORDINO captures brain-wide motor sequence activity, initiated and executed by the subjects – pushing the frontiers of naturalistic fMRI!

9/ SORDINO for resting-state fMRI in awake mice🐭: Using a custom headplate coil, we mapped functional connectivity without restraining body or limbs, showing robust triple-network connectivity and great alignment with Allen Mouse Brain Atlas structural connectivity.

8/ SORDINO offers superior specificity 🎯: Unlike BOLD-fMRI, SORDINO is sensitive to tissue oxygen and CBV changes rather than hemoglobin oxygenation. This can avoid draining vein bias and result in improved accuracy in detecting neuronal activity.