Seydoux Lab Profile
Seydoux Lab

@Seydouxlab

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Welcome to the Seydoux Laboratory! We study how single-cell embryos localize RNAs and proteins to pattern developmental potential.

https://t.co/zlLdhOeWQ3
Johns Hopkins SOM
Joined October 2019
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@Seydouxlab
Seydoux Lab
@Seydouxlab
2 years
Confused about biomolecular condensates? Check out our latest review: https://t.co/eMCRumNJAy Many thanks to G&D and the anonymous reviewers for an awesome review process!
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@LCochella
Luisa Cochella
@LCochella
3 years
Extremely grateful to @NSF for a CAREER Award to my lab, to pursue a project we are super excited about on regulation of morphogenesis by an ancient animal microRNA! Everyone @NSF we have interacted with has been knowledgeable, responsive and helpful. Thank you for your support!
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@Seydouxlab
Seydoux Lab
@Seydouxlab
3 years
Are all phase-separated compartments functional, or are some “accidental condensates”? Check out our new preprint with @PAskjaer to find out more: https://t.co/t8mjKMh0fX
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biorxiv.org
Nucleoporins (Nups) assemble nuclear pores that form the permeability barrier that separates nucleoplasm from cytoplasm. Nups have also been observed in cytoplasmic foci proposed to function as pore...
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@Seydouxlab
Seydoux Lab
@Seydouxlab
3 years
This was a fun interview by @Dev_journal on our recent work: Specialized germline P-bodies are required to specify germ cell fate in Caenorhabditis elegans embryos! https://t.co/LpCl6SBuEU Check out the paper here: https://t.co/eoMHMGaXEH
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journals.biologists.com
Highlighted Article: This paper describes a new condensate in the C. elegans germ plasm, ‘germline P-bodies’, which contain regulators of RNA translation and decay and are essential to specify germ...
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@Seydouxlab
Seydoux Lab
@Seydouxlab
4 years
Pickering stabilization of a dynamic intracellular emulsion: We're excited to share our preprint on bioRxiv! This was a fantastic collaboration with @LeeBioPhysics https://t.co/Hed8DW8kwA
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biorxiv.org
Biomolecular condensates are cellular compartments that form by phase separation in the absence of limiting membranes. Studying the P granules of C. elegans , we find that condensate dynamics are...
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@Seydouxlab
Seydoux Lab
@Seydouxlab
4 years
We are excited to share our new paper "Protein-based condensation mechanisms drive the assembly of RNA-rich P granules" published on eLIFE!
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elifesciences.org
P granule assembly depends in part on protein-protein interactions that drive condensation independent of RNA.
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@Seydouxlab
Seydoux Lab
@Seydouxlab
6 years
Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double‐Stranded DNA Donors @HopkinsMedNews @currentprotocol https://t.co/Z7MQfX3ZUV
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@Seydouxlab
Seydoux Lab
@Seydouxlab
6 years
John Paul posted the weird thing growing on Maddie's plate on Reddit, so hopefully we'll get some insight: What is this weird thing growing on my plate?
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