Jorge Sepulcre Lab
@SepulcreLab
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Our lab focuses on brain imaging studies aiming to understand the large-scale brain networks implicated in human cognition and neurodegenerative disorders.
Yale School of Medicine
Joined August 2019
Excited to see our work highlighted in today's New York Times article exploring the potential benefits of intentional mind wandering in creative thinking! https://t.co/4KqezyLBDe
nytimes.com
Today, let’s get lost in our thoughts.
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Our latest work "Cortical Hubs of Highly Superior Autobiographical Memory" is now published in Cortex! We apply graph theory analysis in resting-state data to describe connectivity profiles associated with this rare form of enhanced memory. Full article:
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🧵Happy to share our last work on tau propagation and smell perception in aging. @LauraOrtizTeran @ThomasNgImaging @AlbersLab Marshall G @will_orwig Kim C @neuroeli Montal V @jokriolo @_PatriziaV Fahkri, Sperling R, Johnson K, @HeidiJacobsLab @SepulcreLab
https://t.co/puhty0bgLi
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I will be talking about how NETWORK MOTIFS can help us understand #tau spreading pathways across systems and at the voxel level. Visit poster 102 at #AAIC24 | @SepulcreLab @IbaiDiezPalacio @HeidiJacobsLab | #connectomics | @Yale @YaleMed @MGHGordon @MGH_RI @MGHMartinos | #ADNI
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In a recent @NatureAging publication, researchers from @MGHMartinos and colleagues investigated early targeting of the locus coeruleus and how it may delay Alzheimer's progression. Read more: https://t.co/2w4OXHVsAc
@heidijacobslab @sepulcrelab @neuroeli @elouisekoops
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And @neuroeli showed that #locuscoeruleus changes may precede cortical tau, predicting future cognitive decline. She also highlighted some of the genetic features associated with this spatial pattern of tau vulnerability! With @SepulcreLab @NatureAging 🎉
nature.com
Nature Aging - In vivo human neuroimaging shows that locus coeruleus (LC) integrity changes precede medial temporal tau accumulation, and jointly predict future lower cognition in older people at...
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🧠 NEW RESEARCH @CommsMedicine – Bueichekú et al. perform multi-modal neuroimaging-based phenotyping of mnemonic anosognosia in the aging brain | @neuroeli @SepulcreLab @_PatriziaV
https://t.co/fFLZrBRrb5
nature.com
Communications Medicine - Bueichekú et al. use multimodal in vivo neuroimaging to investigate the brain characteristics of individuals presenting unawareness of memory loss who are at risk of...
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So happy to see our latest work out! "Multi-modal Neuroimaging Phenotyping of Mnemonic Anosognosia in the Aging Brain" in Comms Medicine. Great collaboration between the @SepulcreLab and @_PatriziaV 's lab!
🧠 NEW RESEARCH @CommsMedicine – Bueichekú et al. perform multi-modal neuroimaging-based phenotyping of mnemonic anosognosia in the aging brain | @neuroeli @SepulcreLab @_PatriziaV
https://t.co/fFLZrBRrb5
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Join us in congratulating four of our 2023 #DistinguishedInvestigators 👏. These #DI will be honored at #RSNA23 in Chicago. For more program details, visit https://t.co/tD5o4CI405.
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Our latest paper 'Creativity at Rest: Exploring Functional Network Connectivity of Creative Experts' is now published in Network Neuroscience! @netneuroscin
https://t.co/oqfGkOdV9y
direct.mit.edu
Abstract. The neuroscience of creativity seeks to disentangle the complex brain processes that underpin the generation of novel ideas. Neuroimaging studies of functional connectivity, particularly...
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.@SepulcreLab and colleagues found that an #MRI shows how #ParkinsonsDisease (PD) disrupts neuronal circuits. Learn how these results lay the foundation for studying functional network reorganization at different stages of PD: https://t.co/ytQjrIzvYm
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New paper out in the Creativity Research Journal, exploring contributions of mind wandering to creative thinking. Thanks to my collaborators @SchacterLab @SepulcreLab @neuroeli @IbaiDiezPalacio @chris_a_kelly
https://t.co/4JntiHMryO
tandfonline.com
Studies suggest that internally oriented cognitive processes are central to creativity. Here, we distinguish between intentional and unintentional forms of mind wandering and explore their behavior...
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In our latest research at @ICS_unav, together with @SepulcreLab, we show how belief networks are organized in different sociodemographic (ie male/female) and ideological (left-winger vs right-winger) groups. Check it out at @SpringerNature:
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📢🥳Congratulations to @vmbotwin and colleagues for the publication "Network Tau spreading is vulnerable to the expression gradients of APOE and glutamatergic-related genes" in @ScienceTM
@SepulcreLab @IIBSantPau 👇 https://t.co/V7d03K484h
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Just published in @ScienceTM -- Network Tau spreading is vulnerable to the expression gradients of APOE and glutamatergic-related genes https://t.co/85S2T9ZCnc
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👏 Masterclass del Dr. Jorge Sepulcre, neurólogo y profesor de la Universidad de Harvard, sobre las redes cerebrales a gran escala implicadas en la cognición humana y los trastornos neurodegenerativos del Alzheimer. 📅 23/05 - 16h Inscríbete en ➡️ https://t.co/sW9VDHC2FW
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Interviews are ongoing for our #BehavioralNeurology-#Neuropsychiatry fellowship across the MGH Departments of Neurology @MGHNeurology & Psychiatry @MGHPsychiatry. 1 year & 2 year tracks available. Details below. @DickersonLabMGH @jacamprodon @SchmahmannLab @LRamirezGomezMD
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Network Neuroscience (2022) 6 (2): 320–338. Multimodal connectome biomarkers of cognitive and affective dysfunction in the common epilepsies. https://t.co/m9foMPADzN
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Special Edition of CrossTalk next Tuesday (6/14) at 5pm EST. We welcome Kenji López-Alt (@kenjilopezalt) world-renowned chef to discuss the creativity and science of the culinary arts with Indre Viskontas (@indrevis). Click the link to register!
crowdcast.io
Register now for CrossTalk Event with Kenji López-Alt on crowdcast, scheduled to go live on June 14, 2022, 05:00 PM EDT.
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