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#Machinelearning finds potential brain cancer drug targets in multi-omics dataset. Read the full article:

Researchers have identified a lifestyle-related metabolite biomarker called gluconic acid that is associated with high blood pressure and increased ischemic stroke risk among Black adults. Learn more:

Today, we honor and celebrate Dr. Martin Luther King, Jr. #mlk #mlkday #martinlutherkingjr #civilrights

🎇 We wish you all a healthy and happy New Year!. #happynewyear #newyear #newyearseve

#Oxytocin could promote growth of new #neurons to repair damaged tissue and may contribute to #neuralcircuit plasticity, opens door to new ways to improve #neurologicalconditions: study #neuralnetworks #brain #brainplasticity #brainresearch #neuroscience.

#AI helps to uncover #molecular mechanism underlying #pancreaticcancer. Findings increase understanding of #disease #pathogenesis and open possibilities for exploring new modalities to treat human #diseases, including #hypertension and #cancer. #AlphaFold2.

Research demonstrates novel #syntheticpeptide's ability to selectively detect/neutralize early #molecular trigger of #Alzheimers, with an eye towards early diagnosis and treatment of other #amyloiddiseases. #Parkinsons #peptides #amyloid #neurodegenerative.

Researchers identify critical inhibitory site in #enzyme, which can lead to rational design of #antibiotics. Team succeeds in identifying #antibiotic which is effective against super #drugresistant strain of #Neisseriagonorrhoeae. #antimicrobialresistance.

Study reveals how viral #toxin produced by #SARSCoV2 #virus may contribute to severe #COVID19 infections. By targeting pathway, it could block #pathogenesis leading to #vasculardisorder & acute #respiratorydistress syndrome without needing to target virus.

Using #artificialintelligence, researchers find evidence that length of #genes explains most of the #molecular-level changes that occur during #aging, which they contend could lead to therapeutics that slow or even reverse process. #AI #machinelearning.

#Optogenetics-based tool allows researchers to control how #neurons respond to electrical input. Using light exposure to change electrical capacitance of neurons' #membranes alters their excitability - which is linked to #brain disorders like #Alzheimers.

Using #machinelearning, researchers developed a virtual #molecular library of thousands of 'command sentences' for #cells, based on combinations of 'words' that guided engineered #immunecells to seek out and kill #cancercells. #cancer #AI #cancerresearch.

Scientists challenge a 70-year-old theory of how #proteins fold in our #cells with profound implications for treating protein misfolding-linked diseases, including certain #cancers, #Parkinsons, #Huntingtons, and #Alzheimersdisease. #cellbiology #cryoEM.

Novel #microscopy technique for #biomedicalresearch captures dynamic #3Dimages across larger areas, maintaining #cellular resolution in three dimensions. Study provides views of #cells interacting in natural state, has potential for new disease treatments.

Researchers have created a spatial #cellatlas of the developing human #lung, describing 144 #celltypes and their interactions in unparalleled detail while uncovering new links between developmental #cells and #lungcancer. #cellbiology #celldevelopment.

#Drugtargets, such as kinase enzymes often involved in #cancer, are difficult to target with traditional drugs. Now, research discovers #IFITM #proteins enable bitopic inhibitors to enter #cells, targeting previously untargetable proteins. #cellbiology.

Bioactive compounds called #glycolalkaloids that are found in many #vegetables have the potential for new #cancerdrugs. In vitro and animal studies are needed to determine which glycoalkaloids are safe, promising to test in humans. #cancer #CancerResearch.

Scientists produce infectious #malaria #sporozoites without mosquitoes, providing ground-breaking progress for #malariavaccines. They manufactured #Plasmodiumfalciparum sporozoites in vitro, a major step to scale up manufacturing of #PfSPZ #malariavaccine.

New drug neutralizes #SARSCoV2 and its #variants by acting as #ACE2receptor decoy. The #virus can't evade decoy as #mutations that would allow it to avoid the drug would also lower the virus's ability to infect cells. #COVID19 #coronavirus #virology #ACE2.

#Heartattack on a Chip replicates key aspects of #myocardialinfarction, may one day serve as testbed for #heartdrugs. Scientists don't understand how #heartcells in healthy/injured parts of #heart communicate but new microscale model could solve mystery.