
Sayed Abdel-whab (ORCID: 0000-0003-2103-0922)
@Sayedabdelwhab
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V: for Virus, Virulence, Vaccine Head of Avian Influenza Lab, FLI, Riems, Germany Priv.-Doz., Habil, Giessen Uni. Cert. Virologist Editor-in-Chief npj Viruses
Isles of Riems, Germany
Joined February 2011
🎓 In my lab, on the island of Riems, we’re hiring a doctoral student (m/f/d) for 4 years! Join our innovative DFG-funded project ImmunoChick 2.0. 📅 Deadline: 25-08-2025 | Start: 01-10-2025.More info & apply 👉
fli.de
job location: Greifswald - Insel Riems application deadline: 25.08.2025
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Happy to announce that the DFG continues to support @ImmunoChick 2.0! Excited to advance innovative research on the avian immune system to improve vaccines, animal health, and zoonosis prevention. 🐔🔬 #ImmunoChick #DFG #AvianImmunology.
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🚨 Duck-origin H5N6 bird flu in China shows stronger binding to human receptors and resists current poultry vaccines. A rising threat to public health. 🦆🧬 #AvianInfluenza #H5N6 #OneHealth.
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RT @LomvardasLab: Wow! 1,700 transgenic mice for the most comprehensive enhancer characterization ever. Leo and Axe….
nature.com
Nature - Human enhancers contain a high density of sequence features that are required for their normal in vivo function.
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RT @RobertPdeVries1: Very happy that our paper on the receptor binding properties of contemporary H3N2 viruses is now published @CellReport….
cell.com
Liang et al. shows how contemporary H3N2 viruses reverted to bind sialylated di-LacNAc at the molecular level. Using complex symmetrical and asymmetric N-glycans, major epistatic interactions were...
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Viral diversity makes the jump but then shrinks fast! New study shows influenza A’s transmission bottleneck happens after infection starts, not during transfer. Host factors may play a bigger role than we thought. 🦠🔬 #FluEvolution #ViralTransmission.
biorxiv.org
For many viruses, narrow bottlenecks acting during transmission sharply reduce genetic diversity in a recipient host relative to the donor. Since genetic diversity represents adaptive potential, such...
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Surprise alert! Unexposed people carry low-level antibodies that can fight H5N1. Could this be a hidden shield against the next flu pandemic? 🦠💪 #H5N1 #FluImmunity #PandemicPrep.
biorxiv.org
The spill-over of Influenza A virus H5N1 clade 2.3.4.4b from cattle to humans highlights the risk of a human H5N1 pandemic. Given the impact of pre-existing immunity on the course and severity of...
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New remote swabbing tool lets researchers safely sample Antarctic seals--> cutting stress, risk, and costs while boosting wildlife disease monitoring in harsh polar conditions!.
biorxiv.org
Remote or minimally invasive sampling techniques are essential in wildlife research, particularly for Antarctic seals. These methods reduce handling time, minimize animal stress, and improve biosec...
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Reinstating RIG-I in chickens sparks a stronger immune response but worsens flu outcomes, shedding light on why chickens lost this gene in evolution to avoid damaging inflammation. 🐔🦠 #AvianImmunity #RIGI #Influenza.
biorxiv.org
Retinoic acid-inducible gene I ( RIG-I ) activates mitochondrial antiviral signaling proteins, initiating the antiviral response. RIG-I and RNF135 , a ubiquitin ligase regulator, are missing in...
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H7N7 LPAIV infection in point-of-lay hens offers partial protection but doesn’t stop HPAIV spread, highlighting risks of silent virus emergence on layer farms. 🐔🦠 #AvianInfluenza #H7N7.
biorxiv.org
H7N7 low-pathogenicity avian influenza virus (H7N7-LPAIV) incursions have preceded emergence of H7N7 high-pathogenicity (HP)AIV at several European layer hen outbreaks. Evidence from a UK layer...
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A live NS1-deficient flu vaccine shows promise in protecting against cattle-origin H5N1 viruses spreading in the US. One nasal dose protected mice from deadly infection. #H5N1 #FluVaccine #OneHealth
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RT @Nucleocapsoid: H5N1 (B3.13) in dairy cattle: study with $950 per cow estimate. 20% of c.3500 herd symptomatic. Random sampling show….
nature.com
Nature Communications - Highly pathogenic avian influenza H5N1 virus has recently caused outbreaks in dairy cattle herds in the United States. Here, the authors describe the clinical features and...
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RT @DuckSwabber: Crows infected with HPAI have limited disease signs, except ruffled feathers and some signs of mental confusion (virus in….
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RT @DuckSwabber: Cool opportunity for a PhD student to work on avian influenza and avian viromes in Sweden. Should be a super fun project w….
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🦠 How does flu hijack your cells?.New study in npj Viruses @NaturePortfolio shows how influenza A virus protein NS1 sabotages our gene expression by targeting nuclear speckles, shutting down host mRNA production from the inside.
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🧫🦠 H5N1 cross-immunity from. H1N1?.A new study shows that A/H1N1 infection but not H3N2 or vaccination boosts antibodies against H5N1 HA & NA. 📉 Baseline H5N1 immunity in humans is low.💉 Enhancing NA responses may improve pandemic readiness.
biorxiv.org
An increase in the number of human cases of influenza A/H5N1 infection in the US has raised concerns about the pandemic potential of the virus. Preexisting population immunity is a key determinant...
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🧬⚠️ Two bird flu subtypes, one deadly scene. H5N1 and H5N5 co-circulated in a seabird die-off on the UK coast, H5N5 also found in dead grey seals. 📍First UK case of dual HPAIV subtypes at one site.
biorxiv.org
H5Nx clade 2.3.4.4b high pathogenicity avian influenza viruses (HPAIV) have been detected repeatedly in Great Britain (GB) since autumn 2020, with H5N1 dominating detections but with low level...
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