Sayed Abdel-whab (ORCID: 0000-0003-2103-0922)
@Sayedabdelwhab
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V: for Virus, Virulence, Vaccine Head of Influenza Lab Priv-Doz. Virology EBVS Diplomat Cert. Virologist EiC npj Viruses Head WSV Train. & Career Dev. Committee
Isles of Riems, Germany
Joined February 2011
We just opened 5 junior group leader positions at the Ignaz Semmelweis Institute in Vienna. We are looking for motivated, enthusiastic young leaders in infectious disease research that complement our current team. More information here:
semmelweisinstitute.ac.at
Training We are committed to train the next generation of basic and translational infectious disease researchers. We believe, young people full of energy and creative ideas can solve problems that we...
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https://t.co/wfA3kSO8jo I was pleased to contribute alongside a multidisciplinary team of experts to an EFSA scientific opinion on the risk of influenza H5N1 (B3.13) in EU dairy cattle, including the potential for food-borne human infections through milk consumption.
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Incredible work by the ACDP HPAI working group (ht to Ralph) for pulling together the impact of HPAI on Procellariiformes. The dataset underlying the upcoming database is now live! 👉 https://t.co/VFxboMW7kW
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#H5N1 @CDCgov @USDA ➡️🇨🇦 Canada: Die-off of hundreds of birds something Manitoba hasn't experienced 'at this scale': biologist - suspect die-off is related to avian influenza after birds in Niverville test positive By Santiago Arias Orozco https://t.co/DIzEtRrsue
cbc.ca
At least 500 carcasses of birds, the majority of them Canadian geese, have been recovered near water streams in southern Manitoba over the last month — a die-off scientists say they have not witnes...
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Most U.S. human H5N1 (clade 2.3.4.4b) viruses remain antiviral-susceptible, but rare baloxavir resistance (PA-I38M) and M2 resistance detected. Ongoing surveillance is essential. https://t.co/6xZG9SkXH1
tandfonline.com
Since October 2024, 55 human cases of influenza A(H5N1), clade 2.3.4.4b, were reported in the US. Sequencing of 46 viruses identified genotypes B3.13, D1.1, and D1.3. Genomes of viruses were analyz...
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2025 flu season in Australia & NZ: unusually long and driven by H3N2 subclade K. Distinct from previous strains, now detected globally. https://t.co/dxavWTXMxq
eurosurveillance.org
In Australia and New Zealand, late outbreaks of an A(H3N2) variant virus termed subclade K extended the 2025 influenza season. Subclade K viruses were genetically and antigenically distinct from the...
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⚠️Mutant H3N2 influenza is starting to spike in US 🇺🇸: 1.9 million illnesses, 19,000 hospitalisations (4.3/100000), 730 deaths, nil paediatric. Last flu season had 287 pediatric deaths, the worst since the Swine Flu epidemic. https://t.co/uv8n9JWlrG ✴️New York, Louisiana,
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Smartphones meet virology: a new nanoparticle assay detects H5, H7 & H10 with PCR-level accuracy in minutes. Fast, sensitive, no cross-reactivity, a powerful tool for early warning. https://t.co/NqmVPRvP66
tandfonline.com
Avian influenza viruses (AIVs) of the H5, H7, and H10 subtypes pose substantial threats to global public health owing to their high pathogenicity, cross-species transmissibility, and potential to s...
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Thousands of samples, one message: early warning signals for H7 in wild birds are weak. But rainfall in SE Australia reliably aligns with H7 outbreaks. Ecology matters for preparedness. https://t.co/3rsgzxvMNJ
biorxiv.org
Adding to the global burden of high pathogenicity avian influenza (HPAI) H5N1, an unprecedented five HPAI H7 outbreaks occurred globally in 2024. Of these, three occurred in southeast Australia, with...
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Finland’s H5N8 vaccine rollout worked: 83–97% seroprotection, boosted T-cell immunity, and cross-reactivity against H5N1 strains from fur farms and US cattle. Strong evidence for cross-protection. #AvianInfluenza #H5N1 #Vaccines
nature.com
Nature Microbiology - Vaccination of Finnish at-risk occupational groups with a clade 2.3.4.4b H5N8 influenza vaccine induced robust antibody and T-cell responses, supporting its potential to...
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H5N1 spread across North America mainly via migratory wild birds, with 46–113 independent jumps into poultry. Backyard birds got infected first. Strengthening surveillance at the wild–agriculture interface is essential. #AIV #OneHealth
https://t.co/k3fHV3dxaM
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H11 avian influenza from wild birds shows dual receptor binding + mammalian-adaptation markers. These viruses can jump further than we think. Surveillance is key. #AvianInfluenza #OneHealth
https://t.co/XIqEvl3Ksj
tandfonline.com
H11 subtype avian influenza viruses (AIVs) have been identified in both wild and domestic birds. H11N9 viruses from wild birds provided the NA gene to human H7N9 virus in 2013 in China, which cause...
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⚠️ BREAKING: ‘Super-Mutated’ Flu Sweeps Britain NHS Declares Early Crisis, Warns of “Worst Winter Ever” as Experts Urge Mask Use Mandatory masks have been imposed in hospitals in London, Lincolnshire, Shropshire, and Oxfordshire amid alarm at infection numbers.
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https://t.co/q5q63aHdkQ H5N1 risk in milk? Pasteurization nearly eliminates it. Raw milk doesn’t. A new model quantifies the difference and highlights key knowledge gaps.
medrxiv.org
The spillover of H5N1 clade 2.3.4.4b into dairy cattle has raised concerns over the safety of fluid milk. While no foodborne infection has been reported in humans, this strain has infected at least...
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The first flu you meet as a child can shape your lifetime risk. 🧬 New data from 54 years of U.S. mortality show strong effects of immune imprinting with big implications for influenza vaccines. https://t.co/5xOudfAMIv
medrxiv.org
Influenza viruses encountered in childhood can leave a lasting immunological imprint. To disentangle the mortality effects of age, the circulating seasonal strain, and immune history, we fit statis...
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🆕 BA.3.2 is designated a #SARSCoV2 Variant Under Monitoring by @WHO. Although it demonstrates antigenic drift & reduced neutralization in vitro, currently approved #COVID19 vaccines are expected to continue providing protection against severe disease. https://t.co/vl4Upi6YHp
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Honored to chair the Virology in One Health session & deliver the keynote at the 1st Int. Online Conference on Veterinary Sciences. Great discussions on viruses from influenza, bovine CoV, herpes in whales, reovirus in crabs, to bacteriophages hunting E. coli! I love viruses :D
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Great new paper: Epistasis helps H3N2 escape immunity, yet HA stability blocks many mutations from ever fixing. Evolution has rules. https://t.co/T9nmMeIEVc
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Fresh data on H9N2 immunity: Inactivated vaccines kick in early TLR5/7, IL-6, IFN-α, Mx1 up within 48 h. Some vaccines deliver high antibody and protection profile, while others not. https://t.co/HNYe7J1ExD
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https://t.co/4P43HOiU5m New H9N2 study: Key HA mutations (30T, 39A, 327R, 373K, 465K, 490R) boost replication, stability, and enable transmission to swine. Long-term poultry circulation drives mammalian adaptation.
link.springer.com
Veterinary Research - The cross-species transmission of avian H9N2 influenza viruses to swine increases the risk of viral adaptation to mammalian hosts. However, the mechanisms by which these H9...
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