Satya Prakash Yadav
@Satyayadav__
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Director- Pediatric Hematology Oncology & Bone Marrow Transplant, Medanta The Medicity . Chairperson-elect -PHO chapter of IAP @pho_india RT are not endorsement
Gurgaon, India
Joined October 2022
🔥 Classical Hodgkin Lymphoma (cHL) & Cytopenias 🧬 Cytopenias at diagnosis = think bone marrow involvement, hypersplenism, HLH, autoimmune cytopenias, marrow suppression from chronic inflammation 🔎 Workup: CBC diff 🧪 smear 🔬 LDH 📈 ferritin 🔥 retics 🧬 Coombs 🧫 CMV/EBV 🦠
nejm.org
Brentuximab vedotin is an anti-CD30 antibody–drug conjugate that has been approved for relapsed and refractory Hodgkin’s lymphoma. We conducted an open-label, multicenter, randomized phase 3 trial ...
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Post-artemisinin delayed haemolysis (PADH) in a case of severe haemophilia with complicated falciparum malaria
researchgate.net
PDF | Background and Aim - Severe falciparum malaria can cause life-threatening complications, especially in patients with bleeding disorders.... | Find, read and cite all the research you need on...
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Burkitt's Lymphoma | ASH Image Bank | American Society of Hematology https://t.co/HpctrQ2ojb
#ASHImageBank
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SMA syndrome - a must know for all physicians
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💼 Summary for Hydroxyurea (Hydrea / HU) — side effects, monitoring & management: ⸻ ⚠️ Side Effects / Risks • 🩸 Myelosuppression → neutropenia, thrombocytopenia, anemia • 🦠 Infection risk (due to neutropenia) • 🩹 Bleeding / bruising (low platelets) • 🧠
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🧬 Essential Thrombocythemia (ET) — with prior thrombosis 🩸 ⸻ ⚡️ Goal: prevent recurrent thrombosis & control plt count 💊 Tx: • Cytoreduction: Hydroxyurea 1st-line 🧪 (Alt: Peg-IFNα, Anagrelide if HU-intolerant) • Low-dose Aspirin 81 mg daily (unless plt > 1000 × 10⁹/L ➜
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Classical Hodgkin lymphoma with owl eyes 👀 on biopsy sample
One of the blood film appearances that medical students need to know about. What is this?
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Pathophysiology of Beta Thalassemia Easy Way to Remember ...... #meded #medtwitter #hematology #blooducation
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🩸 Acquired Factor VIII Inhibitor (Acquired Hemophilia A) 🔹 Definition: Autoantibody against Factor VIII → functional deficiency despite normal synthesis → spontaneous bleeding in previously healthy adults 🧬. ⸻ 🔹 Epidemiology: •Rare: ~1–1.5/million/year. •Often
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View from mountain
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mRNA cancer vaccine for glioblastoma A Promising Start !!
Cancer immunity in a shot. Scientists at the University of Florida have created a breakthrough mRNA cancer vaccine that erased deadly brain tumors in early human trials without chemo or radiation. Tested on four glioblastoma patients, the vaccine reprogrammed their immune
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Time for DUNP19 osteosarcoma & glioblastoma for good !
Big Cancer Breakthrough UCLA Scientists Develop Antibody That Hunts and Destroys Aggressive Cancers UCLA scientists have developed a powerful new cancer fighting antibody, DUNP19, that can both detect and destroy some of the deadliest, most treatment resistant tumors like
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Chemo free therapy for ph+ Acute lymphoblastic leukemia is feasible for some patients
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Hope against Multi drug resistant bugs !
New drug alert! Cefipime (4th gen cephalosporin) in combination with Zidebactam (beta lactamase inhibitor that prevents degradation of cefipime inside the bacteria) has been approved for serious Gram negative Hospital acquired infection with almost 100% cure rates.
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Just before storm ⛈️ in Gurgaon this evening!
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In primates, senescence-resistant cells (SRCs), can not only halt aging but roll back its negative effects Delivered IV, these cells sparked a rejuvenation trifecta—sharper cognition, stronger bones &revitalized reproductive health—without adverse effects
cell.com
Genetically engineered senescence-resistant human mesenchymal progenitor cells can reduce aging markers and improve tissue and cognitive functions in aged macaques, highlighting their potential as a...
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Our immune system is an evolutionary masterpiece. Every day it protects us from the thousands of different viruses, bacteria and other microbes that attempt to invade our bodies. Without a functioning immune system, we would not survive. One of the immune system’s marvels is its
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Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body. The Nobel Prize laureates
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….and Nobel prize in medicine goes to … T regulatory cells
BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
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Heartiest congratulations and best wishes @NicoGagelmann
Finally in Boston! Honored to join @DanaFarber, eager to learn and contribute in this terrific community and place of science, purpose and hope.
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