🚨 New #THRiVElab Publication! 🚨 Our commentary in @MicroResRep summarizes a recent study from @Sara_SShama, @MichelleAsburyR and the MaxiMOM Study team at @SickKids.... #Tweetorial 🧵 Read here: https://t.co/Mnf3MtJKkH

New paper 📢 Breastfeeding shapes developing immune systems. Here we report plasma protein differences at 1-yr in @CHILDSTUDY Spencer Ames @MeghanAzad

Thanks @uoftmedicine for this feature! Have you heard of the Canada Prenatal Nutrition Program? Across Canada, the CPNP provides important perinatal nutrition support to families navigating challenging life circumstances--but funding has *not* increased in over two decades

Please share this survey with any caregivers you may know in Canada and the US so that we can learn more about infant food insecurities.

A HUGE thank you to our incredible team @MichelleAsburyR @DLOConnor0803 @SharonUnger10 @akash__kothari @AdriannaGreco_ @nutrisci_uoft @uoftmedicine @SickKidsNews @SinaiHealth @CAGEFToronto @uOttawa and to our funders @CIHR_IRSC for making this work possible! 10/10

These findings highlight that mother’s milk holds promise for being a potential vehicle to alter the gut microbiota of VLBW infants, which may in turn improve both their short- and long-term health. 9/10

Relationships we observed were often modified by postnatal period, in-hospital feeding practices, and maternal-infant antibiotic use. #Antibiotics can disrupt these relationships, emphasizing the importance of antibiotic stewardship for BOTH mothers and their infants. 8/10

Correlations were also observed between milk and stool microbial consortia, suggesting that multiple milk microbes may influence overall gut communities together. 7/10

Using detailed DAILY feeding data and normalized abundance data, we show dose-response relationships between intakes of several genera from milk and their concentrations in the infant’s gut. 6/10

With direct #breastfeeding, we found that certain #bacteria were much more likely to be shared between mother’s milk and the VLBW infant's gut, including Streptococcus, Veillonella, and Haemophilus. 5/10

We first found that ~35% of bacteria in the VLBW infant gut are shared with those in mother’s milk and that direct #breastfeeding 🤱🏻significantly increases microbial sharing! 4/10

Studies have shown that #HumanMilk bacteria help shape the gut in term infants, but things are different for preterm infants since they face unique challenges like #antibiotics💊, feeding tubes, #fortification, and #DonorMilk - all of which can impact their gut microbiota. 3/10

VLBW infants often develop aberrant gut bacterial communities, which have been associated with conditions like necrotizing enterocolitis and sepsis. While feeding mother’s milk reduces these risks, we don’t yet fully understand how milk microbes impact the VLBW infant gut🤔 2/10

Excited to share the first of my PhD studies exploring relationships between the #microbiota in preterm mother’s milk and the very low birth weight (VLBW) #infant gut across hospitalization - published today in @CellRepMed 🤱🏻🦠 #Tweetorial 🧵 1/10 https://t.co/KnLPOVX6Jc

Thanks for collaborating on this preview @MichelleAsburyR, @DLOConnor0803, @nutrisci_uoft

@SerenaManara, @leonardubois, @martselm congratulations on your fantastic work!

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How do factors like human milk feeding, delivery mode, and FMTs modify microbial transmission from parents to infants?🤔@mcarmen_collado, de Vos & @nsegata explore this in their recent @CellHostMicrobe papers. Check out their beautiful work and our commentary for more! 🧵