Ryan Zarychanski
@RZarychanski
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Professor, Hematology/Critical Care. Clinician-Scientist studying hematologic consequences of critical illness.
Winnipeg, Manitoba, Canada
Joined April 2015
Congratulations Deborah & team. This trial needed be done for years and you figured out how to get it done in a way that compels us all to change practice. Use smaller tubes; take less blood; reduce transfusion, especially at a strained system level. Amazing!
STRATUS Trial published @JAMA_current 🩸Cluster trial 25 ICUs >27,000 patients 🩸Switch to “small-volume” tubes that⬇️blood drawn for lab tests may⬇️RBC transfusion↔️effect on testing 🩸Available, cost-neutral, compatible with analyzers – will you switch? https://t.co/sTkJVyfrgS
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Inspiring Lyonel G Israels Memorial lecture and special session on women leaders in medicine by Dr. Saskia Middeldorp - she won the heart of every Winnipeg’er who attended. What an enormous impact in such a short amount of time. Thank you Saskia!
What an amazing experience to address the Lyonel G. Israels Memorial Lecture today @CCMB_Research. Thanks @RZarychanski and team for hosting me!
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Spectacular field trip hiking the Hunt Lake trail with @MiddeldorpS and Winnipeg colleagues - work hard; play hard, while making memories and friendships together. What a day!!!
#Winnipeg hematology field trip - day 2 of visiting professorship was sooo exciting and fun! Thanks @RZarychanski and hematologists for a great experience at the center of 🇨🇦🙏🏼
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Congratulations Saskia, Mariette, Siobhan and team!
Leaving #ISTH2023? Just a tip for your read on the way home about @ALIFE2trial #ALIFE2
@TheLancet link to the full paper - for free download until July 21st! #heparin #LMWH #pregnancy #recurrent # miscarriage
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Excited & privileged to receive funding from @Research_MB to create skilled jobs, build clinical trial expertise in Manitoba, and provide mentoring opportunities for new researchers - all while improving outcomes for patients with pneumonia! @CancerCareMB @UM_RadyFHS
We are pleased to announce an investment of $500K allocated over 5 years designated to support the ATTACC-CAP trail led by @umanitoba researcher @RZarychanski, this will be the second-largest clinical trial led out of Manitoba. Read full news release: https://t.co/LsO2soXVIq
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Do not miss! - Only 2 more days to @MiddeldorpS. Join virtually or in person. @isth #ISTH2023 @INVENT_VTE @EHA_Hematology @ASH_hematology Find out the latest data! Hear about patience, persistence, collaboration, and passion to improve thrombotic maternal-fetal outcomes.
Looking forward! The day after #ISTH2023 👇🏼
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Calling all those who dare to be inspired! Only 2 more days. Join virtually or in person. ALL are welcome. https://t.co/Bjxz5QE0sP
@MiddeldorpS @UM_RadyFHS @CMA_Docs @DoctorsManitoba @UHN @mcgillu @uOttawa @CPHO_Canada
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There was a little coffee shop where two people arrived and approached the counter. “Five coffees ☕️ please. Two for us and three pending.” They paid, they took their two coffees and left. I asked the waiter. "What’s this about pending coffees?" “Wait and you'll see." Some
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UM’s College of Pharmacy student is doing a superb job presenting the impact of symptom duration prior to hospitalization on clinical outcomes in Covid and whether symptom duration impacts the treatment effect of therapeutic-dose heparin. Well done Quinn! @ISTH @UM_RadyFHS
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Brilliant talk by my friend @RZarychanski on the role of adaptive clinical trials and assessing heterogeneity of treatment effect on #immunothrombosis #ISTH2023 @isth
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Thank you! Just as medical treatments have evolved, so have randomized trials. The next generation of trials will need to designed to detect and quantify heterogenous treatment effects (HTE) so that we can identify patients who benefit or may be harmed. Enough negative trials -
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Great presentation! We have so much to improve in our clinical practice in immunothrombosis.
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It’s time to design and conduct trials differently than we have in the past so we can detect heterogenous treatment effects and identify patients who will benefit or be harmed! @remap_cap @UM_RadyFHS @CancerCareMB @ATTACC_COVID
Brillant presentation by Dr. @RZarychanski on identification of patients that will benefit from heparin/LMWH as an Immunothrombosis-directed agent @ThrombosisCan @canvector
#ISTH2023
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Wonderful presentation by Manitoba’s own Quinn Tays at the International Society on Thrombosis and Haemoatasis Congress in Montreal - if therapeutic heparin is started for Covid on the ward, reduce the dose to prophylaxis if the patient requires ICU-level care
Quinn Tays from @umanitoba presents on Impact of heparin on disease state transition in hospitalized, non-critically ill patients with COVID-19; secondary analysis of an international multi-platform RCT at 13:30 in room 511 @Rzarychanski @MarcCarrier1 @LanaCastellucci #ISTH2023
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We hope you'll join us! Hear from Dr. @MiddeldorpS on "Women in High Places." Register by June 21 https://t.co/FecDpI05Ro
#Winnipeg #CareerSuccess
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A Special Session with Dr. Saskia Middeldorp not to miss! -- Leading & succeeding from a female perspective. Join us in person, or virtually, from wherever you are. All our welcome @MiddeldorpS
@isth
@canvector
@INVENT_VTE
@UM_RadyFHS
@SOGCorg
@ASH_hematology @CCMB_Research
Join us on June 29 for a thought-provoking lecture by Dr. @MiddeldorpS on "Women in High Places." Gain valuable insight on strategizing for career success while balancing work, family & life. Don't miss this empowering session! RSVP by June 21 https://t.co/FecDpI05Ro
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All are welcome! Incredible privilege to have Dr. Middeldorp in Winnipeg, Canada to deliver the Lyonel G Israels Memorial Lecture. Please join us in person, or virtually, from wherever you are. @MiddeldorpS @isth @canvector @INVENT_VTE @UM_RadyFHS @SOGCorg @ASH_hematology
➡️Attention all! Join us for the 18th Annual Lyonel G. Israels Memorial Lecture with Dr. Saskia Middeldorp on "Thrombosis, Thrombophilia, & Pregnancy" on June 29 at noon - in person or online! Register by June 22 at https://t.co/IJD7QYRX82
#Thrombosis #Thrombophilia #Pregnancy
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Disgusting, unethical PLACEBO control trial in colon cancer just so Fruquitinib can win I will show you that placebo should not have been the control arm, & the IRBs & FDA failed 🧵 First, this trial tests a new drug vs. placebo (sugar pill) in patients dying of colon cancer
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Thanks to @CellAutophagy and colleagues for this important piece
cdnsciencepub.com
For the past 6 months, there has been an ongoing revolution in Iran after the brutal death of Zhina (Mahsa) Amini in morality police custody. Iranian universities’ professors and students have been...
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