Finally
#MedTwitter
and
#MedX
I found a way to remember antiarrhythmic classes without EVER forgetting or having to memorize. Read this thread to learn how:
PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) inhibitors have changed the landscape of cardiology forever.
This is a Tweetorial🧵on why.
And it starts in 1999, with a French family named HC2.
Is this the best paper of the year?
Can a lot of HFpEF be prevented/cured by exercise?
Should we stop skipping the physical activity part of the office visit? Interested in thoughts
FINISHED RESIDENCY! Wow. And walking out of the hospital the last time…
Just kidding, I’m back here to start
@hopkinsheart
cardiology fellowship tomorrow!
My
#Cardiology
paper of the year: Daily Step Count in
@JACCJournals
The optimal steps to ⬇️ CVD events is NOT THAT HIGH! Totally achievable!
Its easy to get discouraged by the marathoners, bodybuilders, etc. Sure that's great, but not necessary. Do enough, the benefits follow
So you've heard a lot of stuff, you've read a lot, maybe you listened to our podcast
@cardionerds
on it, and yet something is still missing.
TRIGLYCERIDES NEED A TWEETORIAL!
Let’s get right into it with 2 big points to start
Haven't read it all yet, but what a document out in
@JACCJournals
!
Decision pathway on HFpEF management should be a game-changer across
#MedTwitter
. Grateful to giants like
@MKIttlesonMD
@JJheart_doc
and others for putting this together
Incredibly grateful to stay
@hopkinsheart
for cardiology fellowship! Immense thanks to the
@OslerResidency
and countless mentors along the way.
AND pulled off the couples match with
@AmandaSu490
, joining
@JohnsHopkinsDOM
GI fellowship! Excited for what’s ahead
#ACC24
REDUCE-AMI another blockbuster
Beta-blockers with NO reduction in myocardial infarction or death in pts with preserved EF post-MI
Massive finding likely with big implications for
#Cardiology
practice
Incredibly grateful to share this piece out in
@JACCJournals
today! Just to have learned from the mentors involved was one of the great privileges of my training and education to date.
Seems an exciting and under-discussed paper out in
@JACCJournals
LBBB pacing outperforming Biventricular pacing is massive! Assuming
#EPeeps
can move toward this broadly, is BiV CRT necessary any longer?
Really excited to say I'll be joining
@umichCVC
starting in July for training in advanced cardiac imaging!
Grateful to the mentorship and time of many, especially Drs.
@MMukherjeeMD
@rblument1
@ErinMichos
@venkmurthy
and Madamanchi.
(Still a UW fan though, go Badgers!)
Potential game-changing paper out in
@JACCJournals
Should P2Y12 be the go-to antiplatelet for secondary prevention? Would love to hear
#CardioTwitter
thoughts!
Honored and incredibly excited to join the
@JACCJournals
team as a Social Media editor!
Thanks to the editorial board at
#JACC
for the opportunity. Thrilled to start getting the word out to
#CardioTwitter
while sharing great science and
#MedEd
!
BRIEF TWEETORIAL: ALTERED MENTAL STATUS MNEMONICS!
MIST (See the mist below) gets support and for good reason. Metabolic, Infection, Structural, and Trauma/Toxins hit the high points. Here's another option that also gives some sense of what to check and when.
GO TIME
One of the most interesting slides I've seen from RELIEVE-HF
#ACC24
Strikingly different results in subgroups by EF! Incredibly divergent responses for differing physiology
Fascinating article on out of hospital arrest without ST elevation out in
@JACCJournals
Would love to hear thoughts on how this may effect the current management paradigm
What a unique and interesting piece by Dr.
@adnanalkhouli
and colleagues on the left atrial appendage in
@JACCJournals
Phenomenal work in answering a question few every thought to ask. Absolutely worth a read
Great patient summation on the role of ASA in prevention today.
@JAMA_current
#cvprev
Aspirin for Prevention of Cardiovascular Disease | Cardiology | JAMA | JAMA Network
Great for
#MedTwitter
, but really anyone with something to learn
A quick, easy, mostly passive way to learn things you often otherwise have to memorize…
Just use your phone's Home Screen
Here's how:
🔥QUICK TEACHING/MEMORY TRICK on FeNa! 🔥
Question: How can we remember FeNa and FeUrea calculations?
☑️Keep things on the UP and UP...
☑️...and HIGHER letters go first.
We'll get into that soon. First...what is FeNa and why it is classically used?
What were your top
#MedTwitter
reads of the year?
For me, this review in
#JACCAdvances
on Optimal Perfusion Targets in Cardiogenic Shock was incredible. Absolutely one to keep around and refer back to next year!
@JACCJournals
Have 📖 much of CAC limitations in setting of acute chest pain, use in statin determination, etc
However, if pt w/ CP gets a CT in the ED and CAC at same time is 0...is this not helpful in diff diagnosis?
Shout out
@Gurleen_Kaur96
for the graphic that reminded of this question!
Back with another
#CardsReview
! Continuing the learning and focus on cardio-obstetrics, sending out this excellent tweetorial by
@eunicedugan
and
@karanpdesai
Find more
@Cardionerds
episode 61 on peripartum cardiomyopathy here!
Excited to share a recent piece on important highlights in
#cvprev
! Had the privilege of co-authoring the section on Physical Activity under the mentorship to Dr.
@ErinMichos
.
Thanks to all co-authors for the opportunity to learn from them!
1/11 Really excited to share our recent work, led by the always incredible mentorship of Dr.
@ErinMichos
, on Hepatocyte Growth Factor (HGF) and incident heart failure!
This one's a bit of a deep dive, so let's get into a short Tweetorial to explain, starting with a poll!
#ACC24
PREVENT trial is up and it's a big one
PCI for non-flowing limiting, high-risk is shows ⬇️ cardiovascular events!
Wow this is certain to generate discussion. Implications for management could be huge
Really privileged to contribute to this work led by Dr. Trost and many other mentors
@hopkinsheart
Cardiac imaging is a hugely exciting place to be right now, stay tuned!
#ACC24
Ultimate DAPT trial with some incredible results
⬇️ bleeding WITHOUT ⬆️ in cardiovascular events
How do the guidelines change to reflect this? Fellows and attendings on consult teams everywhere watching
@JACCJournals
So incredibly excited to share this work many years in the making on nonobstructive CAD and cardiac events! So many hours went into this, and I am incredibly grateful to all contributors. A few points on the work below:
Will be compiling lists of great free
#CardioTwitter
education in challenging areas like imaging, where lot of the teaching content is VERY💰
I'll start with below, awesome video in MR assessment. Highly recommend for
#MedEd
while on echo rotation!
@DxRxEdu
Right! Don't memorize, understand principles
What happens when the RV is stressed? Tachycardia right? V1-V2 sit over the RV so may seen T-wave inversions (Or more). +/- RBBB. MAYBE S1Q3T3. Take the context and go from there
Learned much of this from a great doc in residency
Incredible piece in
@JACCJournals
by some of the best in clinical trials on incorporating recurrent events
Absolutely worth reading for those in research and clinicians alike!
Oral PCSK9 inhibitors! Complete game-changer. Mic drop at the end of
#ACC23
Serious
#Cardiotwitter
question: How long until everyone just takes these from age 30ish?
Prevention guidelines in 2030s will be wild
My quick, ⬆️or ⬇️, top 3 takeaways from
#ACC24
with explainations in thread below:
1) Polypharmacy is ⬇️!
What a conference for trimming the meds. B-blockers post-MI took a hit in REDUCE-AMI, while shorter DAPT duration got ⬆️ support from the Ultimate DAPT trial. What's next?
Fancinating paper and PHENOMENAL infographic out in
@JACCJournals
!
Really interesting finding, and potentially management-changing. NNT 56 isn't crazy given CAD burden out there
Would love to hear
#CardioTwitter
thoughts on paper and data
This paper from legends
@SJGreene_md
@robmentz
et. al. was a great one
I spent all of residency being told torsemide was better than furosemide. Clearly some of that is changing
When would torsemide still be preferred?
Honored to be nominated as a
@JohnsHopkinsDOM
Clinical Research Finalist for work under Dr.
@ErinMichos
on biomarkers in HFpEF. More to come!
And grateful to be associated with an incredible group of nominees. Congrats to
@DrSpaulding_PhD
for the amazing
#cvprev
work and award!
How many people can say they they spent their 1 year anniversary in the
@hopkinsheart
CCU and on
@HopkinsGIHep
consults?
Grateful to
@AmandaSu490
for the support on this wild journey
(picture below not from hospital today)
More fantastic free
#MedEd
in
#CardioTwitter
imaging here, this video on prosthetic aortic valve assessment
Tough topic broken down really well. Worth checking out
☑️FeNa is the fractional excretion (Fe) of Sodium (Na). That how we get Fe-Na. The FeNa is just the amount of Na our kidney lets leave the body
☑️It's value has been of some debate, but in theory it can help differentiate PRE-renal and INTRA-renal kidney injury
Why?
Really nice work in
@JAMACardio
showing the benefits of beta blocker cessation in HFpEF and chronotropic incompetence ESPECIALLY for those with small LV
Good reminder for providers below!
On a 1-10 scale of
@CardioNerds
-yness, this is an 11
Excited to launch a new initiative,
#NerdsWords
! This will encompass fun, engaging opportunities for learning/retaining key
#CardioTwitter
teaching points
First up: Heart Failure Guidelines CrossWord
Not an interventional person, but COMPLEX-PCI is one of my favorites from
#ACC23
/
#WCCardio
Such a slam dunk that on my read should really change management.
To
#CardioTwitter
out there, when would you not PCI w/ image guidance?
Who’s ready for another
#CardsJC
?
TOMORROW, 10/19, 8pm EST!
Incredibly grateful to the experts and
#FITs
joining, awesome learning experience ahead! See you and the rest of the
@CardioNerds
then!
Highlighting
#ACC24
trials I'm excited about in the THREE DAYS before the conference!
First up: REDUCE-AMI
After 2023 Chronic coronary disease guidelines w/ 2b recommendation for reassessment of long-term B-blocker post-MI w/ EF >50%, more data here will be huge
@JACCJournals
Medicine boards being scheduled for second month of fellowship or start of career as an attending is just brutal.
We’re all transitioning, busy, and trying to provide the best patient care possible. Is promoting that not the point of exams anyway? How do we improve?
#MedEd
Excited to share our work on HFpEF and HGF at
#AHA20
! The story of inflammation in HFpEF and the role of
#cvprev
continues to evolve. Grateful to all mentors on this work, and especially to
@ErinMichos
for helping to lead this project. More to come!
Excited to join an incredible group of colleagues/mentors as a
#ACC23
social media ambassador for
@JACCJournals
!
Should be an incredible conference, looking forward to sharing
#SoME
of the highlights here
If you want to learn more about lipids and dyslipidemia in general, see our review Contemporary Management of Dyslipidemia below.
Thanks to Drs.
@TLeucker
,
@maciejbanach
,
@SethShayMartin
, Jones, and Toth for the mentorship!
Required reading. Early contender for top review paper of the year
Thank you and congrats to authors
@Brian_Houston12
, Evan Brittain,
@RyanTedfordMD
for this work!
Results for
#ACC24
STEP-HFpEF DM Trial
Baseline medication use in the trial. Why are OVER 80% of pts with HFpEF on beta blocker when we know this worsens symptoms?
If you're not reading this
@JACCJournals
series on complications of acute MI, you're doing it wrong
Recent piece on ventricular septal rupture excellent. Much to learn from med students to attendings!
Zilebesiran in
#ACC24
KARDIA-2 looks like a new option in HTN management!
Will patients buy into another injection medication, especially for something hard to see/feel like ⬆️ BP?
@JACCJournals
We were honored to publish our study led by
@RichardAFerraro
in the
@JCardFail
. We found that the higher circulating levels of novel cytokine Hepatocyte Growth Factor (HGF) was independently associated with increased risk of incident
#HFpEF
but not HFrEF in MESA study
#biomarkers
HUGE news! New Chronic Coronary Disease guidelines out in
@JACCJournals
!
Many incredible graphs/graphics and information, a lot more to read here. Congrats to all involved, including
@hopkinsheart
@DrMSWilliams
!
How else do we diagnose? ABIs!
ABI = Ankle-brachial index.
You've probably heard this term thrown around a lot, but do you know how to get them and read them?
Well we – mostly
@karanpdesai
's hard work – put together a whole fancy thing below to break it down.
Hugely honored to receive a scholarship from
@MayoClinicCV
for their Echocardiography course
Incredible material so far, excited to learn and share knowledge with others!
INCREDIBLY excited to fire up a new project
@CardioNerds
: THE CARDIOVERSE!
This is a group for cards fellows to share cases/ask questions on concerns inside/outside fellowship. We hope to create a outlet for inter-institutional knowledge
Sign up below!
Not going to win any awards for surprising results, but really important work showing how important risk factor mitigation is to ⬇️ cardiovascular disease in
@JACCJournals
Cumulative exposure is crucial,
#ASCVD
risk reduction should be a focus early!
#ACC24
IVUS versus angiography-guided PCI for ACS
SIGNIFICANT difference in target-vessel failure between groups
Question for the IC experts: When would you NOT use IVUS?
PHENOMENAL piece on hypertrophic cardiomyopathy
Really great images with doppler which can be tough to differentiate, especially early in
#CardioTwitter
and
#MedEd
training
CASE TWEETORIAL! We're going to talk about PLATYPNEA- ORTHODEOXIA!
Here's an early preview of what we'll be discussing from the
@cardionerds
case report with Allegheny General Hospital!
🚧Under Construction 🚧
Excited to release a new project soon! Idea is this: There are 3-4 publications a week all of
#MedTwitter
should know about. We discuss/break down the details
We want to hear from you! Message below for ideas of papers to review
Fantastic
#ACC23
/
#WCCardio
discussion - and title slide - on
#HFrEF
now!
Have been thinking about this a lot in the prevention space as well.
Question for
#CardioTwitter
, should we shift focus more to consistent implementation?
When posting ECGs, please provide teaching and context
Very little is learned from comments like “Nice one!” or guesses that are often incorrect
Give the learners something to learn and everyone will be better for it
Finished nights in the
#COVID
ICU. One of the most humbling experiences of my life.
But I want to thank my colleagues in the non-COVID ICU. They are shouldering a huge burden, basically double work w/ us away, w/o the praise that comes from working on COVID units. Thank you
Really interesting results from CLEAR trial! Another great tool for lipid lowering
Here’s my
#ACC23
/
#WCCardio
question for everybody out there: When to use over PCSK9?
But what if there was another way. What if we could make the effects of PCSK9 inhibition last longer? What if we could make them last forever?
PCSK9 Tweetorial Part II. Coming soon
Completely awesome
@JACCJournals
review of Angina with Nonobstructive Coronary Arteries (ANOCA)!
Major topic on the rise. Definitely recommend reading for anyone in
#Cardiology
and
#MedTwitter
Want to learn more? See our recent paper where you can find this and other highlights on contemporary lipid management
Grateful to Drs. Toth,
@TLeucker
@SethShayMartin
@maciejbanach
and Jones for their guidance on this piece!
More interesting data from
#ACC24
EMPACT-MI trial
Notably outpatient HF events not in the primary outcome for study. But look at this subgroup analysis!
SGLT2 continues to show incredible results
@CardioNerds
Twitter Journal Club (
#CardsJC
) is TONIGHT!
Join us at 8pm EST for a discussion of FAME3 with an incredible list of
#CardioTwitter
and
#MedEd
guests/experts. Can't wait to learn from this group and others.
See you there!
Really happy to share or recent review of Nutrition and Physical Activity Recommendations from US and European Cardiovascular Guidelines under the guidance of Dr.
@ErinMichos
and with the tremendous help of
@NicoleMFischer1
and Helen Xun. A few takeaways:
So let's recap:
⬆️PCSK9 in hepatocytes leads to⬇️LDLR on hepatocytes cell surface
⬇️ LDLR on the cell surface leads to⬆️ LDL in the bloodstream
⬆️ LDL in the bloodstream leads to ⬆️coronary artery disease, peripheral artery disease, and plaque generally
Really excited to share our piece on Nutrition and Exercise in
@ACCinTouch
! Incredibly grateful to
@SethShayMartin
,
@rblument1
, and Dorothy Davis for the mentorship on this piece, and to
@ErinMichos
for the ongoing support in this work elsewhere.
Really excited to serve as a
@JACCJournals
social media ambassador at
#AHA2022
this week!
Should be a lot of fun with a lot of great learning. More to come this weekend!