Reuven Gordon
@ReuvenGordon
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Professor, FIEEE, FOptica, FSPIE, PEng
Victoria, BC, Canada
Joined February 2012
Deep learning for accurate classification of extracellular vesicles from cancer and healthy cells. Delighted to have this successful New Frontiers Research Fund project published today:
nature.com
npj Biosensing - Accurate label free classification of cancerous extracellular vesicles using nanoaperture optical tweezers and deep learning
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New preprint from fantastic @HFSP grant: Mohsin Naqvi @maria_zach_ @jrkumita Ivet Bahar Satya Saha Anupam Banerjee @stonybrooku @ReuvenGordon Mert Gur Zeynep Yilmaz @PittTweet Shang-Hua Yang @NTHU_TAIWAN @SanderTansLab Michael Ohlmeyer
biorxiv.org
Protein phosphatase 2A (PP2A), an important therapeutic target, comprises a scaffold subunit PR65 composed of 15 HEAT (Huntingtin/elongation/A-subunit/TOR1) repeats, a catalytic subunit, and one of...
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Label free dynamics of single proteins -- demo video. I love seeing the actual experiment demonstrating how straightforward this approach is (albeit Cuifeng and Mohsen's microfluidics is way more advanced than anything we have attempted). https://t.co/BPbTDPzALi
app.jove.com
Current single-molecule techniques to characterize proteins typically require labels, tethers, or the use of non-native solution conditions. Such changes ...
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Several Optica journals are seeking to fill Editor-in-Chief positions for 2026 for 3 years:
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The energy landscape of a single disordered protein (tau) and the impact of PTMs is resolved. An important step to understanding the function and dysfunction of disordered proteins from their conformational ensemble. Not yet peer reviewed.
biorxiv.org
Intrinsically disordered proteins (IDPs) and proteins with intrinsically disordered regions (IDRs) are integral to many biological processes including neurotransmitter regulation, microtubule...
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https://t.co/a6noCApZXU looking forward to talking at @LMU_Muenchen CENS tomorrow. Streaming online.
cens.lmu.de
All events at a glance
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Just had an editorially invited manuscript editorially rejected.
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Label-free Single Molecule Sensing -- the first conference in this Gordon Research Conference series. Outstanding invited speaker program just announced: https://t.co/VvENvJ07wW Submit your applications early! #singlemolecule #labelfree
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Stability maximum of protein conformations observed on a single molecule using real-time label-free approach. #biophysics #singlemolecule
#NOTs
https://t.co/JA81c1sL0A
pubs.acs.org
Nanoaperture optical tweezers allow for trapping single proteins and detecting their conformational changes without modifying the protein, i.e., being free from labels or tethers. While past works...
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Optical #scattering methods offer groundbreaking insights into single biomolecule analysis, enabling precise label-free detection of #proteins. Explore how light reveals the unseen in molecular #biophysics: https://t.co/PNR23ImbMJ
@ReuvenGordon @Cuifeng_AOP
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https://t.co/NZF8XuTqAQ Single molecule label-free small molecule interactions for drug discovery. SMAPs. Outstanding work by Annie, Maria and co-authors. #singlemolecule #labelfree #drugdiscovery
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That’s a wrap! What an incredible #QUBIC2024 Symposium! Huge thanks to our inspiring speakers and the amazing QUBIC community for three days of quantum biotech brilliance! Excited for the groundbreaking discoveries ahead! 🔬🚀 #QuantumBiotechnology #LifeChangingTechnology
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@ReuvenGordon opening the @arc_qubic Annual Symposium with a fanatic talk on unlabelled measurements of the dynamics of single proteins, and applications in #cancer and #neurodegenerative diseases.
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Inspiring talk by @ReuvenGordon on applications of plasmonic trapping to bio and quantum systems #AIP2024
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I think I put in a broken link:
nature.com
npj Biosensing - Energy landscape of conformational changes for a single unmodified protein
Observing the conformational energy ladscapes of single unmodified proteins directly: https://t.co/uaXito9qBV…
@Matthew73212312 @Cuifeng_AOP @SileNicChormaic
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Observing the conformational energy ladscapes of single unmodified proteins directly: https://t.co/uaXito9qBV…
@Matthew73212312 @Cuifeng_AOP @SileNicChormaic
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Matthew Peters from the University of Victoria @uvic won the best young researcher oral presentation award 'Uncovering the energy landscape of single protein conformational changes in nanoaperture optical tweezers' at #S3IC2024 sponsored by @CSB_Journal. Congratulations
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Another outstanding S3IC - looking forward to the next one!
The third day of #S3IC2024 started with Prof. Reuven Gordon's plenary presentation about recording energy landscapes of single proteins with nanotweezers. #S3IC2024 #nanosystems #singlemolecule #PremC #conference #Paris
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In a conference with such amazing talks it’s hard to feel i deserved this, but honoured nonetheless. Hoping to be back next year again! @S3IC_Conference
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Seeing single proteins (without modifications/labels). The technologies are advancing rapidly: https://t.co/2PJPSl2kor Smaller. Faster. @CambridgeUP
cambridge.org
Optical scattering methods for the label-free analysis of single biomolecules - Volume 57
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