Rebecca Riddle
@RebeccaRiddle1
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Cambridge and AstraZeneca scientists developed a 3D vessel-on-a-chip using the OrganoPlate® platform, revealing platelet roles in inflammation. This model accurately replicates interactions between platelets, neutrophils, and endothelial cells. https://t.co/D1I6klD2oy
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PhD student @RebeccaRiddle1 of the @HarperLabCam has entered an amazing angiogenesis image showing perfusable 3D vessels-on-a-chip, this is in a competition run by @emulateinc - get voting 👉 https://t.co/BlEBhnW4KW
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And to complete a day of fascinating talks, @RebeccaRiddle1 from @HarperLabCam is telling us all about neutrophil transmigration!
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NC3Rs grant holder @HarperLabCam and colleagues have used an inflammation-on-a-chip model to reveal the role the extracellular matrix plays in modulating neutrophil transmigration, which could be applied to improve the accuracy of drug development models.
nature.com
Scientific Reports - Endothelial inflammation and neutrophil transmigration are modulated by extracellular matrix composition in an inflammation-on-a-chip model
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Excited to share my first, first author paper using the @MIMETAS_3D OrganoPlate to build an #inflammation-on-a-chip model
🔎 The @HarperLabCam at @UnivCamPharm used the #OrganoPlate to develop a humanized 3D in vitro #inflammation-on-a-chip model to recapitulate neutrophil transmigration across the endothelium and subsequent migration through the #ECM. Read more: https://t.co/y5oAs6q6TO
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