REVISION
@REVISION_trial
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Early REperfusion Therapy with Intravenous Thrombolysis for Recovery of VISION in Acute Central Retinal Artery Occlusion: phase III randomized trial
Tübingen, Deutschland
Joined January 2024
🚀 Kicking off international expansion at #ESOC2025 Since Oct '22: 92 patients at 22 German sites - already 2× faster than THEIA & TenCRAOS. Still aiming for 422! Thanks to all at our first in-person Investigator Meeting. 📩 Get in touch if your site wants to join!
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Congrats to my dear friend Jean-Claude Baron! At #ISC25 honored with the David R. Sherman Award for his lifetime work on the pathophysiology of acute ischemic stroke. Mon ami, your pioneering work in visualizing the penumbra in humans has shaped stroke research & treatment !👍👏
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👏👏 Frankfurt Team @Dr. Jan Hendrik Schäfer (neurology) and @Prof. Thomas Kohnen (ophthalmology) enrolled patient #65 into the #revision_trial intervention trial Total enrollments 136 patients ⬆️💪 @SvenPoli
@CarstenGrohmann
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🎉 Many thanks especially to the Sites that could recruit new patients in the last four weeks: - Aachen - Frankfurt - Lübeck - München (LMU) - Regensburg - Sulzbach - Tübingen Keep going 💪 @REVISION_trial
@SvenPoli
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🚨REVISION Trial! 👁️Does Early REperfusion therapy with intravenous alteplase help recovery of VISION in acute central retinal artery occlusion? ⭕️Adaptive design with interim analysis ⭕️Up to 422 participants to be recruited https://t.co/9GLLFKWT9P
@SvenPoli
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Congratulations to @SvenPoli, who was just elected to join the Board of Directors of the @ESOstroke 🎉
We are happy to present the new Board of Directors for ESO and extend a warm welcome to our new members! Together, we look forward to driving innovation & excellence in #strokescience! Learn more: https://t.co/34iiAwqVH2
#ESOC2024 #stroke #neurology #voiceofstroke #stroketwitter
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Just Accepted! 🗞️Early #REperfusion Therapy with Intravenous #Alteplase for Recovery of #VISION in Acute Central Retinal Artery Occlusion (REVISION): Study Protocol of a Phase III Trial. https://t.co/iCvATw902c
@SvenPoli @REVISION_trial
journals.sagepub.com
Rationale: Meta-analyses of case series of non-arteritic central retinal artery occlusion (CRAO) indicate beneficial effects of intravenous thrombolysis when in...
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Just Accepted! 🗞️Early #REperfusion Therapy with Intravenous #Alteplase for Recovery of #VISION in Acute Central Retinal Artery Occlusion (REVISION): Study Protocol of a Phase III Trial. https://t.co/iCvATw9xRK
@SvenPoli @REVISION_trial
journals.sagepub.com
Rationale: Meta-analyses of case series of non-arteritic central retinal artery occlusion (CRAO) indicate beneficial effects of intravenous thrombolysis when in...
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👁️🧠 Study protocol of the @REVISION_trial (IVT in central retinal artery occlusion) just published at @IntJStroke 🔔 Motivated EU stroke centers may contact us and still join @SvenPoli @HIHTuebingen @uktuebingen @CarstenGrohmann @BoehringerDE @BMBF_Bund
https://t.co/EnQgXLvCxc
journals.sagepub.com
Rationale: Meta-analyses of case series of non-arteritic central retinal artery occlusion (CRAO) indicate beneficial effects of intravenous thrombolysis when in...
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Featuring keynote lecture from Anne Hege Aamodt @AnneHegeAamodt from the University of Oslo whose work validated clinical efficacy of tenecteplase. She will update on treatment of strokes in the eye (CRAO) and TenCRAOs trial. @brianmacgrory @SvenPoli @vbiouss @OanaDumitrascu5
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🙌 Big thanks to Teams @LMU_Uniklinikum, @uktuebingen and most importantly Team @UKL_Leipzig for randomizing their 1st patient 🥇into the #revision_trial interventional study (#38, overall 88 patients). @DominikMichalski @JohannPelz
@FockeZiemssen @ClaudiaJochmann
@RitaLachmund
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Another patient recruited in REVISION. Congratulations to local investigators in Regensburg @MariaAndreaGamulescu (Ophthalmology) and @FelixSchlachetzki (Neurology) 🥳 #UKRregensburg 🙌
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Another patient recruited in REVISION. Congratulations to local investigators in Regensburg @MariaAndreaGamulescu (Ophthalmology) and @FelixSchlachetzki (Neurology) 🥳 #UKRregensburg 🙌
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Hats off again to @LMU_Uniklinikum for recruiting a new Patient 17-00016 🥳 Keep going ! 💪 #revision_trial
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👏 Congratulations to the REVISION team of the LMU Munich for enrolling 2 patients in a row! @Siegfried Priglinger @Marc Mackert @Michael Czihal @Lars Kellert @Konstantinos Dimitriadis @LMU_Uniklinikum 33/422, 87 to go until interim analysis 💪 #revision_trial
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Fascinating talks at the 2024 @StrokeBern @StrokeSchool
#CRAO by @SvenPoli
#sICH by @kiliantreurniet
#TIA by LinxinLi
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1st enrollment in the new year 🎉 3rd in Aachen 🎉 🎉 Big thanks to PIs @Dr. Kürten, @Prof. Walter, @Dr. Reich, @Dr. Pinho ! PHANTASTIC contribution to @REVISION_trial ! 32 patients enrolled, 88 left to interim analysis KEEP IT ROLLING IN 2024 💪
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📢Great new paper by first author @TogeislerMD from the Department of #Cardiology and Angiology @uktuebingen & our own @SvenPoli, head of the #Stroke and #Neuroprotection Lab at the HIH.
In the ATTICUS trial, among pts w/ embolic stroke of undetermined source and cardioembolic risk factors, apixaban was not superior to aspirin in preventing new ischemic lesions on MRI and was comparable in rates of clinically relevant bleeding. https://t.co/l3OMFcRTQF
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