Well done Prof Steve Nicholls. Cost effectiveness of Bempedoic acid based on Clear Outcomes published .

Cost effectiveness of LPa testing in high income countries . Well done @ZANFINA and LPa Task Force .

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Additionally, among those discharged within a year, 19.7% reached goal, compared with 15.8% of those discharged over a year prior to interview, requiring median reductions of 42.3% (IQR: 7–92.9) and 49.5% (IQR: 13.3–99.8), respectively.

In those with a first CV event vs. those with recurrent events, goal attainment were 17.7% and 17.0%. requiring median reductions of 46.8% (IQR: 10.4–98.9) and 45.4% (IQR: 10.6–94.1).

Those with vs without a family history of premature ASCVD had similar rates, at 16.4% and 17.7%, requiring reductions of 44.8% (IQR: 13–96.5) and 46.8% (IQR: 9.8–97.1).

self-reported FH, 17.3% achieved goals, similar to 18.2% among those without FH, requiring median reductions of 46.9% (IQR: 12.5–99) for those with FH and 44.1% (IQR: 9.2–95.2) for those without.

For PAD) and CKD higher attainment rates than those without these conditions seen; PAD patients needed a median LDL-C reduction of 32.0% (IQR: 0.5–81), and CKD patients required a reduction of 43.1% (IQR: 5.6–96.5) to reach goal.

For diabetes, 20.9% achieved goal vs 14.8% without diabetes, requiring median reductions of 40.4% (IQR: 6–89.1) for patients with diabetes and 51.0% (IQR: 15.4–103.6) for patients without diabetes.

further % reductions of 43.3% (IQR: 8.7–91) and 59.8% (IQR: 19.5–120). Age differences seen with 18.6% aged ≥60 years reaching goal vs 16.1% of those below 60, requiring further median reductions of 41.5% (IQR: 8.6–90.3) and 51.5% (IQR: 13.2–105.2)to reach goal.

Gap analysis in Interaspi of distance from goal in specific subgroups.Distance from LDL-C goal < 1.4 mmol/L.Males had higher attainment than females for all lipid goals, with 18.4% and 13.8%, respectively, achieving goal .

Pleased to share our latest Interaspire paper on global lipid goal attainment . Still poor globally. Better with combo Tx. Non-HDL and apoB goals shouldn’t be applied when TG is low/ normal . I.e they should be lower .

Passion flowers and their non edible fruit are also really showing up this year . Hard work over 10 years paying off

RT @PCVDJournal: Effect of inclisiran on lipid and mechanical vascular profiles in familial hypercholesterolemia subjects: results from a s….

Video of the garden

The grapes are now coming into their own in our garden

RT @mvaduganathan: Wow, the game has changed! #SURPASSCVOT meets its primary & secondary endpoints in first *head-to-head* CV outcomes tria….

RT @CianPMcCarthy: Obicetrapib is a selective CETPi which ⏬ LDL-C by ~36%. Now in @AmericanHeartJ, we discuss the rational/design of the ph….

RT @MeralKayikcoglu: Published in Atherosclerosis; Our joint editorial by @society_eas EC & the @ATHjournal editorial board — reaffirming….

RT @BaimInstitute: Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk.DOI: 10.1056/NEJMoa2415820.Contributed by Bai….