Stefan Pfeffer
@PfefferCryoLab
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Cryo-electron microscopy, structural biology of molecular machines, ribosome-associated processes
Heidelberg, Germany
Joined October 2020
Great collaboration with the Melnikov Lab @SergeyVMelniko1 @UniofNewcastle and the Hill Lab @chillzaa @YBRI_UoY. Congratulations to all authors, in particular the shared first authors Karla Helena-Bueno and Sophie Kopetschke @S_Kopetschke.
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Out just now at @NatureComms: using cryo-EM and cryo-electron tomography, we provide evidence that structurally heterogeneous ribosomes can cooperate in protein synthesis in bacterial cells:.
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RT @SergeyVMelniko1: 1/2 Here we unexpectedly find that protein S20/L26—identified at the dawn of ribosome research but then deemed a ribos….
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A great collaboration with the Schiebel Lab @Zmbhh. @UniHeidelberg and the Gruss Lab @UniBonn. Congratulations to all authors, in particular the shared first authors Qi Gao, Florian Hofer, Bram Vermeulen @BramV98 and Sebastian Filbeck!.
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Online today at @NatureComms: in a major team effort, we reveal the structural mechanisms for centrosomal recruitment and organization of the human microtubule nucleator γ-TuRC:
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Great collaboration with the Schiebel and Mayer Labs @Zmbhh @UniHeidelberg. Congratulations to all authors, in particular the shared first authors Anjun Zheng, Bram Vermeulen @BramV98.and Martin Würtz @martin_wuertz.
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Out just now at @NatureComms and a great start into the New Year: we reveal how yeast cytoplasmic γ-TuRC is assembled and activated by dimeric CM1 motifs of the receptor protein Spc72 and how the microtubule polymerase Stu2 binds to promote MT assembly.
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RT @ZmbhH: Congratulations to Martin Würtz, who yesterday received the Nikon Young Scientist Award 2024 for excellent research in cell biol….
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We have an open PhD position to explore structures of gamma-tubulin ring complexes using cryo-EM approaches here in our group @ZmbhH. @UniHeidelberg. Please apply via the Heidelberg Biosciences International Graduate School @HBIGS_HD :
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We still have open PhD positions here in our cryo-EM group @ZmbhH @UniHeidelberg. Please apply via the Heidelberg Biosciences International Graduate School or directly send us your application documents.
We have two open PhD positions to explore structures of ribosomes and gamma-tubulin complexes using cryo-EM approaches here in our group @ZmbhH @UniHeidelberg. Please apply via the Heidelberg Biosciences International Graduate School @HBIGS_HD:
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We have two open PhD positions to explore structures of ribosomes and gamma-tubulin complexes using cryo-EM approaches here in our group @ZmbhH @UniHeidelberg. Please apply via the Heidelberg Biosciences International Graduate School @HBIGS_HD:
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Great collaboration with the Schiebel Lab @Zmbhh @UniHeidelberg and the Gruss Lab @UniBonn. Congratulations to all authors, in particular the shared first authors Bram Vermeulen @BramV98, Anna Böhler and Qi Gao @QIGAO31314616.
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Out just now @embojournal: our cryo-EM structure of the native RanGTP-induced γ-TuRC-capped microtubule, revealing a surprisingly asymmetric minus end architecture with direct implications for microtubule regulation and modulation during spindle assembly.
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We still have ERC-funded PhD positions open in the lab! If you are interested, please apply!.
We have three open PhD positions funded under our #ERCStG 'RiboStress' to explore how cells remodel the activity and molecular organization of the translation machinery in response to stress. If you are interested apply via the HBIGS graduate program:
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We have three open PhD positions funded under our #ERCStG 'RiboStress' to explore how cells remodel the activity and molecular organization of the translation machinery in response to stress. If you are interested apply via the HBIGS graduate program:
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RT @ZmbhH: If you want to read a short summary of the projects of the three new @ERC_Research Grantees #ERCStG Daniela Duarte Campos, Kerst….
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RT @UniHeidelberg: Fünf ERC Starting Grants gehen an die Universität Heidelberg – Europäischer Forschungsrat fördert Vorhaben in der Moleku….
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I am very excited and grateful to receive an #ERCStG from @ERC_Research. A really exceptional opportunity to pursue cutting-edge research!. Many thanks to @UniHeidelberg , @ZmbhH , HDcryoNET, our collaborators and of course my group @PfefferCryoLab for having made this possible.
The ZMBH celebrates three prestigious ERC Starting Grants #ERCStG for our young PIs Daniela Duarte Campos, Kerstin Göpfrich @KGoepfrich, and Stefan Pfeffer @PfefferCryoLab. Congratulations to this triple success and to the other two grant recipients of @UniHeidelberg!!!.
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RT @ZmbhH: The ZMBH warmly welcomes Kerstin Goepfrich @KGoepfrich from @mpi_mr_hd as a new professor and research group leader. Her lab's….
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Congratulations, Erik! Very well deserved!. We will dearly miss you and wish you all the best for your next journey!.
Successfully defended my PhD last Friday after 4-year journey in @PfefferCryoLab. Huge thanks to my colleagues and great supervisor Stefan Pfeffer. Now it is time to move to the USA and join @JimahLab and #teamtomo to investigate malaria related parasites.
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