Peter Siska
@PeterJSiska
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Physician Scientist @ University Hospital Regensburg
Regensburg
Joined August 2020
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๐จ Exciting data at #ESMO25! @katy_beckermann presented the Kidney Cancer Research Consortium trial: ๐ Phase 1b/2 study of ipi + nivo + ciforadenant (A2A R antagonist) in 1L ccRCC Immunometabolism meets IO in kidney cancer. ๐ฅ #RCC #ImmunoOncology #ESMO2025
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๐ก OPTIC RCC: precision oncology in action! Using RNA-seq cluster biology to enrich for response in frontline #RCC. ๐น 76% ORR in angiogenic clusters with nivo+cabo ๐น Ipi+nivo enrolling immune clusters next Next steps โก๏ธ expand IO arm & move toward liquid biopsy to replace
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Wonderful seeing you again, Katy! Hard to believe how far things have come since our Rathmell*2 lab days โ and how much progress weโve seen in RCC therapies since then. Always a pleasure to catch up!! #KidneyCancer #Immunometabolism #GU25
So much of the joy of #ESMO25 comes from the people ๐ Great catching up with brilliant colleague and friend @PeterJSiska , after bonding 8 years ago under the mentorship of @JeffRathmell & @KimrynRathmell ๐ฌ Still deep in conversation about T-cell metabolism in kidney cancer โ
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Great thanks to the Working Group Medical Oncology (@AIO_Onkologie) for the scholarship! See you at #ESMO25
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I am deeply shocked by the news of the cowardly attack on Slovakian Prime Minister Fico. Violence must not be existant in European politics. In these hours, my thoughts are with Robert Fico, his family and the citizens of Slovakia.
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Dr @Oferman1 cancer #mmunotherapy guru @HebrewU SPECTACULAR TALK! reviews the nectin family of receptors and describes new anti-PVR AB that restores DNAM1 activity and T cell/NK cell function/Clinical trial has started at 5 sites. 22 patients doses. @sitcancer #TIMO2024
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A brand new paper from @MarinaKreutz lab showing what Hydroxyglutarate does to the immunogenicity&metabolism of myeloid and AML cells! Possible combinations of anti-glycolytic drugs and epigenetic modulators for AML in the future? ๐๐ฉธ https://t.co/Zt7P4320p5
@Haematologica
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Congrats Kim !!!
BREAKING: @POTUS announced his intention to appoint internationally recognized kidney cancer expert, Dr. W. Kimryn Rathmell, as the 17th Director of NCI. https://t.co/KbSatwFXsE
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BREAKING: @POTUS announced his intention to appoint internationally recognized kidney cancer expert, Dr. W. Kimryn Rathmell, as the 17th Director of NCI. https://t.co/KbSatwFXsE
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New #JITC article: MCT4 blockade increases the efficacy of immune checkpoint blockade https://t.co/DmVPuBBYRM
@BablNathalie @MarinaKreutz
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It was a great honor to present at the JSIC7 as a keynote speaker! Thanks to Wolf Hervรฉ Fridman and Eric Tartour for this opportunity and to the whole organizational team for great work! #Immunotherapy #CancerResearch #metabolism
๐๐ฆ๐๐๐ณ - ๐ฅ๐๐ฉ ๐น๐ฒ ๐ฏ๐ญ/๐ฌ๐ญ ๐ฎฬ ๐ญ๐ณ๐๐ฌ๐ฌ ๐ฝ๐ผ๐๐ฟ ๐น๐ฎ ๐๐ฎ๐ฏ๐น๐ฒ ๐ฟ๐ผ๐ป๐ฑ๐ฒ "๐๐ป๐ท๐ฒ๐๐
๐ฒ๐ ๐ฑ๐ฒฬ๐ณ๐ถ๐ ๐๐๐ฟ ๐นโ๐ฎ๐ฐ๐ฐ๐ฒฬ๐ ๐ฎ๐๐
๐ป๐ผ๐๐๐ฒ๐น๐น๐ฒ๐ ๐ถ๐บ๐บ๐๐ป๐ผ๐๐ต๐ฒฬ๐ฟ๐ฎ๐ฝ๐ถ๐ฒ๐" โก๏ธ ๐๐ป๐๐ฐ๐ฟ๐ถ๐ฝ๐๐ถ๐ผ๐ป : https://t.co/cyTYMRhZth
#JSIC #immunooncologie
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How are CD8 T cells in human tumors epigenetically "ticking"? Happy to share a new paper @MolecularCell where we collaborated with Chris Schmidl and his team to get new insights on TIL from kidney cancer and other tumors!
Online Now: Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8+ Tย cells
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Got a chance to listen to excellent talks @KeystoneSymp #Immunometabolism and also to give a talk about our work in #COVID19 Immunometabolism! Btw, altitude sickness + jet lag is a weird combination :)
Kicking off the Keystone with exciting talk by our Keynote speaker @JeffRathmell with 3 stories, all unpublished! @KeystoneSymp
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Our editor @DrTimPImmuno is attending the #ImmunoMetabolism @KeystoneSymp in Keystone Colorado. Reach out to him to learn more about @NatureComms or to discuss potential submissions in the field of immunology and immunometabolism. https://t.co/5AlfD05uCD
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One of the most extraordinary videos Iโve ever seen. The first woman is holding up a sign that says โtwo wordsโ.
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n=2 -> Nature? I beautiful paper with cutting-edge technologies, a ton of data, and a hot topic. But still, n=2.. come on :) https://t.co/vSQFuOCMh5
nature.com
Nature - Infusion of CD19-directed chimeric antigen receptor T cells into two patients with chronic lymphocytic leukaemia resulted in complete tumour remission and persistence of the infused cells...
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