Pâmela Lukasewicz
@Pamlukasewicz
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Research Assistant Professor at University of Pittsburgh @LabPascoal
Pittsburgh, PA
Joined September 2011
In our new paper, we show that neuroinflammation in Alzheimer’s follows a two-wave pattern of harmful effects: 1️⃣ First wave: triggered by amyloid-β (Aβ) 2️⃣ Second wave: driven by widespread tau pathology 📄
alz-journals.onlinelibrary.wiley.com
INTRODUCTION Current literature presents conflicting results regarding the impact of neuroinflammation on Alzheimer's disease (AD)-related neurodegeneration. While some studies suggest that neuroin...
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In our new study @NatureComms, Dr Soares et al show that CSF total tau, often used as a marker of neurodegeneration, is more strongly linked to synaptic degeneration than axonal or neuronal loss in Alzheimer’s disease. Check our paper here🔗 https://t.co/AP74CkgmsX
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We thank Dr Eric Siemers for his insightful comment on our recent publication, “Utility of Plasma GFAP as a Secondary Endpoint in AD Trials,” highlighting the growing potential of plasma GFAP in AD trials @LabPascoal @TharickAPascoal 👇👇👇 https://t.co/mhsZm5le03
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🚨In our latest study @jpreventionalz1, Dr Abbas and @Pamlukasewicz show the potential of plasma GFAP as a secondary outcome in AD clinical trials across the disease continuum. https://t.co/rLz3seyFPb
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Out now 👇🏼👇🏼👇🏼
New paper alert🚨 Our new study led by @dtleffa & @guilhermepovala published @alzdemjournals links genetic risk for ADHD to more severe dementia. Check here:
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New paper alert🚨 Our new study led by @dtleffa & @guilhermepovala published @alzdemjournals links genetic risk for ADHD to more severe dementia. Check here:
alz-journals.onlinelibrary.wiley.com
INTRODUCTION Epidemiological studies indicate a link between attention-deficit/hyperactivity disorder (ADHD) and elevated risk of dementia. However, the impact of ADHD on cognition and Alzheimer's...
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It was a tremendous honor to host the first AAIC Neuroscience Next Hub held in Pennsylvania at the University of Pittsburgh on Monday, as part of the 2025 edition of this global conference! We are immensely grateful to our all attendees, both in person and online, who
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Last week, @boston25 news featured our CliPAD study, a clinical blood-based biomarker study in Pittsburgh, that we will hopefully expand our reach on soon! @PittResearch @UPMC
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We are 4 weeks away from hosting our AAIC Neuroscience Next Hub at the University of Pittsburgh! Join us for a full day of science and community building on Monday, February 24. Register for free today!
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Tremendous effort by @guilhermepovala @TharickAPascoal working with many others to harmonize tau PET. Some upfront work needed by users and independent evaluation underway, but check out their visual calculator they made https://t.co/wY7mtLtonq Really looking forward to the
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Join us and the University of Pittsburgh for AAIC Neuroscience Next on Feb. 24, 2025. Hear from Pittsburgh researchers, dementia experts, community leaders and caregivers. Register here: https://t.co/VXIS6OxC5u
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There’s still time to join us for a day of learning and connecting at the AAIC Neuroscience Next! 📅 Monday, Feb. 24, 2025 📍 University Club, Pittsburgh 🍴 Networking lunch and evening reception 🆓 No cost to attend. Register here: https://t.co/QO12vAn1gh
#AAICNeuro
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We are excited to invite everyone to AAIC Neuroscience Next 2025 at the University of Pittsburgh! 🎉 Join us for insightful talks on the latest neuroscience advances. Register now: https://t.co/XhhuSYB6fi
#AAICNeuro @alzassociation
forms.office.com
We are pleased to announce the program for the University of Pittsburgh Hub of AAIC Neuroscience Next 2025, organized by our lab. Mark your calendars for Monday, February 24, 2025, and register now ( https://t.co/QO12vAmtqJ) to join us in Pittsburgh! This conference intends to
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We are very happy to be the single most funded research lab by the Alzheimer’s Association in the country @alzassociation @AlzGPA. Thanks for all the support to fight AD Walk to End Alzheimer's 2024
wpxi.com
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Don’t miss this opportunity! Register today 👇🏼👇🏼👇🏼
AAIC Neuroscience Next Pittsburgh Hub will kick off with @LiddelowSA showcasing his groundbreaking research on astrocytes. Plus, we'll spotlight 4 early-career researchers—one could be you! Submit your abstract now. Registration is free! https://t.co/uOLMWGz7k2
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Check out our new paper discussing the use of biomarkers in AD clinical trials. 👇👇👇👇 https://t.co/tdkWrzvXNu
Paper 4: Insights into the use of biomarkers in clinical trials in Alzheimer's disease by @TharickAPascoal and colleagues: https://t.co/JYSzZwf9Va
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ADI World Alzheimer Report 2024 is out! Honored and grateful for the opportunity to contribute alongside people I immensely admire. https://t.co/PFRrFAOS7w
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🚨Our study from @zimmerneurolab is out! We found consistent alterations of the glutamatergic system in AD through a systematic review+meta-analysis of 69 studies evaluating levels of several key components of the system. Check out our work @MolPsychiatry: https://t.co/Em1dlmmkVc
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You won’t want to miss the @alzassociation AAIC Neuroscience Next in Pittsburgh! 👇👇
We are excited to announce that Pittsburgh will be a hub for AAIC Neuroscience Next 2025! Stay tuned for program details—coming soon. We can't wait to welcome you in person (or virtually) to our hub. @LabPascoal
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