
Pamela Kanellis
@PamelaKanellis
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Research can improve our world. An advocate for equity, inclusion and social justice. Focused on #brain research. Posts are my own.
Canada
Joined February 2011
Delighted to be partnering with BD2 to support the first international site as part of the BD2 Integrated Network to advance our understanding of bipolar disorder and enhance care. Congratulations to the team led by Dr. Jess Fiedorowicz @OttawaHospital.
🌍 We’re excited to partner with @BrainCanada to bring our first international site, Ottawa Hospital Research Institute, into the BD² Integrated Network. This step helps ensure research reaches those living with #bipolar disorder globally. Learn more:
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#AAIC25 potential opportunities to block transport of pathogenic molecules from gut to brain, and also use this transport to bypass BBB and deliver therapies
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#AAIC25 identify pathways that may be transporting pathogenic molecules between brain-gut; what if you use these pathways to deliver therapeutics
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#AAIC25 evaluating critical care patients for markers of neurodegeneration and find high gfap and greater inflammatory responses; implications for higher risk of dementia
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#AAIC25 astrocytes reactivity and neurodegeneration biomarkers - GFAP - propose astrocytes act as bridge between brain and periphery
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#AAIC25 Glia inflammation and activation may be part of early AD and neuroinflammation and cell death may be part of vicious cycle of progression
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#AAIC25 Propose chronic inflammation leads to microglia cell death and may drive deposits of beta amyloid
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Pattern of earlier age of menopause and increased tau tangles, synaptic biomarkers, and cognitive decline - hormone therapy might reduce risk #AAIC25
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#AAIC25 menopause increases risk of dementia - earlier menopause has increased numbers of TAU tangles
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Women are at greater risk of dementia and earlier age of menopause places women at greater risk of dementia and CVD risk #AAIC25
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Fibrinogen and role in Alzheimer’s disease and potential biomarker and druggable target? #AAIC2025
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Sleep may be a modifiable risk factor explaining sex differences in Alzheimer’s disease #AAIC2025
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Women are disproportionately affected by Alzheimer’s disease - we need research to understand why and to better prevent and treat #Aaic2025
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AAIC For All: Community — Free For the Public to learn about the research and progress -
alz.org
People living with Alzheimer's or dementia, caregivers and families can learn about the latest dementia science and research at this free event.
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