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Pasquale Paolisso Profile
Pasquale Paolisso

@P_Paolisso

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MD, PhD, FESC |Cardiovascular Center Aalst, Belgium🇧🇪 |Cardiology, Sant'Andrea University Hospital, Rome, Italy🇮🇹|SoMeTeam #improvingHeartFunction

Joined October 2020
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@P_Paolisso
Pasquale Paolisso
9 months
Our State-of-the-Art Review on Multimodality Imaging in the Diagnostic Work-Up of Patients With Cardiac Masses is now out on @JACCCardioOncology @JACCJournals 👇 https://t.co/4dovzIyTd0 Role of current multimodality imaging and future directions for their applications: 👥For
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@MartineGilard
Martine Gilard
4 days
Evaluating changes in absolute coronary flow & microvascular resistance in patients with AS undergoing TAVI: no changes immediately after TAVI. Over time, remodelling of the left ventricle is assoc. with increased hyperaemic perfusion https://t.co/jrAOn35JEK @EuroInterventio
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@P_Paolisso
Pasquale Paolisso
11 days
🎯 To assess the association of glucometabolic parameters w/ T4aMI in NSTEMI pts undergoing PCI. 🩸Admission blood glucose (ABG), glycated hemoglobin (HbA1c), and stress hyperglycemia ratio (SHR) were tested. 👥 Consecutive NSTEMI patients undergoing PCI from the AMIPE
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@P_Paolisso
Pasquale Paolisso
16 days
We’re delighted to present our clinical case from the Cardiology Unit at Sant’Andrea University Hospital, showcasing the multidisciplinary management of a patient with HFrEF and multiple Valvular Heart Diseases. A special thank you to the @iheartfunction (iHF) Educational
@iheartfunction
Improving Heart Function (iHF)
16 days
New clinical case from @P_Paolisso, Giose Vinselli & Francesco Cefalì! 82-y/o male with HTN, T2DM & recurrent HF admissions presents with worsening dyspnea (NYHA III). What do the EKG, labs, CXR & TE reveal — and what’s your next step? 🤔 🔎 https://t.co/NVPo8835RK
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@FrancescoPaneni
Francesco Paneni
17 days
Delighted to share our new study on the link between air pollution, chromatin remodeling and brown fat dysfunction 🧡 Kudos to #SanjayRajagopalan and team! https://t.co/4KStRMCyB9 Press release from @uzh: https://t.co/rOsBBKE1H5 @CardioZurich @Unispital_USZ #CTEC
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news.uzh.ch
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@P_Paolisso
Pasquale Paolisso
20 days
🎯To quantify the cardiorenal benefits of combination regimens with GLP-1RA, SGLT2i, and/or finerenone versus corresponding monotherapies. 👥Systematic review and meta-analysis of post hoc analyses of RCTs and 10 observational studies that met prespecified inclusion criteria.
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@RobertHermanMD
Robert Herman, MD, PhD
23 days
This could have been a “boring” STEMI activation. What happens when you wait for ST elevation to develop?
@EM_RESUS
Sam Ghali, M.D.
2 months
Here's a video I made breaking down this very important #ECG that was recorded in a 60-year-old man before he went into cardiac arrest #FOAMed
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@EuroInterventio
EuroIntervention
23 days
In patients with severe aortic stenosis, absolute coronary flow and microvascular resistance do not change immediately or 6 months after TAVI. Yet, reverse LV remodelling is associated with improved hyperaemic perfusion, highlighting the dynamic interaction between coronary flow,
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@iheartfunction
Improving Heart Function (iHF)
28 days
Remember the recent HFrEF case shared by Mustafa Goktug Erata & Mehmet Birhan Yilmaz? Part 2 is now available: the case of a 36-year-old male patient diagnosed with Becker muscular dystrophy. ➡️ Find out which strategy the team selected: https://t.co/40J96MaOe8
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@smithECGBlog
Stephen W. Smith
1 month
Australian ACS guidelines 2025 - The OMI has officially arrived! - ED Guidelines. https://t.co/92GWWoe61W
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edguidelines.com
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@hahn_rt
RTHahnMD
1 month
10 Issues for the Clinician in Tricuspid Regurgitation: 2025 ACC EDCP  https://t.co/WVeKnC4OiW  @JACCJournals @ACCinTouch @escardio @purviparwani @iamritu
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@P_Paolisso
Pasquale Paolisso
1 month
📌Sub-analysis of the EmDia trial (NCT02932436) 🎯To assess changes in lipid profiles driven by Empagliflozin use in HF patients. 👥 Lipid analysis of blood plasma from 144 pts was conducted using 4D-LC-TIMS/IMS lipidomics and repeated after one and twelve weeks of treatment.
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@iheartfunction
Improving Heart Function (iHF)
1 month
Case by Mustafa Göktuğ Erata & Mehmet Birhan Yilmaz: 🧔🏻36-yo with Becker Muscular Dystrophy, ADHF 🔎 Echo: HFrEF, dilated LV ⚠️ Meets ESC advanced HF + several AHA “I NEED HELP” markers → ~46.5% 1-yr mortality How would you treat this patient? https://t.co/40J96MaOe8
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@P_Paolisso
Pasquale Paolisso
2 months
📌DAPAHEART trial: a single-center, 4-week, randomized (1:1 dapagliflozin 10 mg vs. placebo), double-blind, controlled study. 🎯To assess the long-term impact of dapagliflozin on CFR and EAT thickness in T2DM patients with CAD. 👥N=16 pts w/ T2DM+CAD were enrolled in the
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@DFCapodanno
Davide Capodanno
2 months
The 2025 ESC/EACTS guidelines on the management of valvular heart disease have just been released, with an important update: the age threshold for the Heart Team to consider TAVI instead of surgical intervention has been lowered from 75 to 70 years in patients with tricuspid
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@CJCJournals
CJC Journals
3 months
🔓 For a limited time until August 16, we are offering free promotional access to a new article in #CJC! 🌐 This study links CT-derived extracellular volume fraction (ECV) to diastolic function changes before and after TAVI. Findings highlight ECV's potential as a biomarker for
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@P_Paolisso
Pasquale Paolisso
3 months
🎯New Review Highlights Adipose Tissue Drug Targets. Epicardial & perivascular adipose tissues (EAT & PVAT) are emerging as key players in cardiovascular disease -and now, as promising drug targets.🫀💊 This review dives into: ✅ DPP4, GLP-1R, SGLT-2i advances ✅ AT-specific
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@PowerfulMedical
Powerful Medical
3 months
🔥 Published this month: Three NEW external validation studies all point to one conclusion: AI can detect acute coronary occlusion where contemporary ECG criteria fail!
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@iheartfunction
Improving Heart Function (iHF)
3 months
💊 Can acetazolamide speed up decongestion in acute heart failure with volume overload? The ADVOR trial explored the effect of adding it to loop diuretics in ADHF hospitalised patients. A concise take by Hajer Yakoubi & Rim El Mejri↩️ https://t.co/Ma2SFUTsLo
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@P_Paolisso
Pasquale Paolisso
3 months
🎯 Meta-analysis to provide the NNT and efficacy of GLP-1RA in reducing risk of myocardial infarction (MI). 👥109,846 pts from 25 studies. Risk-reduction effect of GLP-1RA were pooled using pairwise meta-analysis with a random-effects model. The primary outcome was MI, and
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@P_Paolisso
Pasquale Paolisso
4 months
🫀 Cardiometabolic HFpEF phenotype (cmHFpEF) is rising fast, linked to obesity, hypertension, and chronic inflammation. 🔬 New insights reveal how metabolic stress, immune shifts, and epigenetic changes drive this condition. 🧬 Targeting metabolism, inflammation & chromatin
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