#PedsICU #Bestof2024 collection has just been published. Put together by @OsamaHosheh @DrToyinOcholi @Dr_Hari_Krishna with inputs and spanish translation from @sgdambrauskas. The collection includes 33 articles. Pubmed collection [ https://t.co/HubrmZLeJ1] has 32 articles

#PedsICU #PedsCICU

👀 Sneak peek at the Brain Trauma Foundation Guidelines for the Management of Penetrating Traumatic Brain Injury, Second Edition CCR Journal Watch  https://t.co/Sp06oA6IDG

6. SUDDICU - Selective Digestive Decontamination during Ventilation in the ICU ➡️ No mortality benefit at 90 d 27.9% vs 29.5% OR 0.94 ➡️ Resistance mixed: fewer resistant isolates in trial patients but ecology noninferiority not met CCR Journal Watch https://t.co/Sp06oA7gte

5. - BICARICU 2 - Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury ➡️ Multicentre RCT severe acidemia + AKI, n=640 ➡️ No 90 day mortality benefit 62% vs 62% but RRT lower 35% vs 50% CCR Journal Watch https://t.co/Sp06oA7gte

4. SONIA - A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia ➡️ Pragmatic RCT in Kenya, n=2180 ➡️ 30-day death 22.6% vs 26.0% with steroids (HR 0.84, P=0.02) ➡️ AEs similar; serious steroid-related 0.5% CCR Journal Watch https://t.co/Sp06oA7gte

3. ANDROMEDA-SHOCK-2: CRT-targeted resuscitation ➡️ Multicentre RCT, n=1467 ➡️ CRT-PHR better on 28-day composite, win ratio 1.16 ➡️ Benefit from fewer days on vital support, mortality similar CCR Journal Watch https://t.co/Sp06oA6IDG

2. EVERDAC: deferring arterial lines in ICU shock ➡️ RCT (n=1006) comparing early vs deferred arterial catheterisation ➡️ 28-day mortality similar (34.3% vs 36.9%) — noninferior ➡️ Arterial-line complications lower (1.0% vs 8.2%) CCR Journal Watch https://t.co/Sp06oA6IDG

#LIVES2025 Hot Topics Session 1. SOFA-2: updated organ dysfunction score ➡️ 3.34M ICU patients in 9 countries ➡️ 6 systems retained with modern supports incl ECMO ➡️ AUROC ~0.79–0.81 for ICU mortality, slightly better than SOFA-1 CCR Journal Watch https://t.co/Sp06oA6IDG

We are launching our next #PARDS trial in @LA_Rednetwork What is the effect of alttitude in clinical outcomes? 60+ centers participating now from LATAM #PedsICU Check it out! https://t.co/MzvMAuDOJl

And importantly the @HeartandStroke Canada Full Highlights of the 2025 American Heart Association's Guidelines, including Paediatric Resuscitaiton. @SickKidsCCM @SickKidsNews https://t.co/7jk4V7jgas

The @ERC Paediatric Life Support https://t.co/8HffdWCrqx

The @AHAScience Peds Advanced Life Support

The @AHAScience Peds Basic Life Support https://t.co/voTOeb8ZzS

Thread.... Big day yesterday launching the Pediatric Life Support: 2025 @Ilcor_org International Liaison Committee on Resuscitation Consensus on Science With Treatment Recommendations & The @ERC_resus and AHA/AAP Guidelines! @AHAScience Enjoy!! #PedsICU #NeuroPICU

#PedsICU #ILCOR

Clancy Laws et al: Analgesia, Sedation, and Neuromuscular Blockade in Pediatric Severe Traumatic Brain Injury: Secondary Analysis of the “Approaches and Decisions in Acute Pediatric TBI Trial” (ADAPT) Link: https://t.co/eDpJXBTcSi @neurocritical #neurocritcare

To PIC or not to PIC? #SALTY trial between @paccman_asia & @LA_Rednetwork once again Out now! #PedsICU @PICJournalWatch https://t.co/RiTQTk8pL7

The National Neonatal Audit Programme (NNAP) has published its 2024 Summary Report, sharing key findings, national recommendations, and data on how neonatal care delivery varies by ethnicity. Explore the reports 👉 https://t.co/pNO8ennaO1

We’ve got the latest #PedsICU collection (Sep 2025) for you - https://t.co/YjoF5qfS9h created for you by @DrToyinOcholi @Dr_Hari_Krishna @OsamaHosheh Also in #PICCHub app. AOTM: https://t.co/eHZsAtC93q - Epi v. Norepi feasibility RCT in Peds septic shock

Latest collection (from the month of Sep 2025) of #PedsICU articles published few days ago: https://t.co/gDpMvKAspi Put together by @DrToyinOcholi. cc: @Dr_Hari_Krishna @OsamaHosheh Also in #PICCHub app.