💊NAPLEX MedFact. Opioids cause pupillary constriction because they stimulate the mu-opioid receptors in the brainstem, specifically in the Edinger–Westphal nucleus of the oculomotor nerve pathway. ☑️This increases parasympathetic outflow to the eye, leading to contraction of
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SGLT2i & UTI: Continue or Stop? 🧩 Key Question: What happens when patients with T2DM on SGLT2 inhibitors develop a new-onset UTI? Should therapy be continued or discontinued thereafter? 🔍 Key Finding (EHJ, 2025 | doi:10.1093/eurheartj/ehaf788) In >61,000 T2DM patients on
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